TY - JOUR
T1 - Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
AU - Spina, Gabriele
AU - Spruit, Martijn A.
AU - Alison, Jennifer
AU - Benzo, Roberto P.
AU - Calverley, Peter M. A.
AU - Clarenbach, Christian F.
AU - Costello, Richard W.
AU - Donaire-Gonzalez, David
AU - Durr, Selina
AU - Garcia-Aymerich, Judith
AU - van Gestel, Arnoldus J. R.
AU - Gramm, Marco
AU - Hernandes, Nidia A.
AU - Hill, Kylie
AU - Hopkinson, Nicholas S.
AU - Jarreta, Diana
AU - Kohler, Malcolm
AU - Kirsten, Anne M.
AU - Leuppi, Jorg D.
AU - Magnussen, Helgo
AU - Maltais, Francois
AU - Man, William D-C
AU - McKeough, Zoe J.
AU - Mesquita, Rafael
AU - Miedinger, David
AU - Pitta, Fabio
AU - Singh, Sally J.
AU - Smeenk, Frank W. J. M.
AU - Tal-Singer, Ruth
AU - Vagaggini, Barbara
AU - Waschki, Benjamin
AU - Watz, Henrik
AU - Wouters, Emiel F. M.
AU - Zogg, Stefanie
AU - den Brinker, Albertus C.
PY - 2017/8
Y1 - 2017/8
N2 - Background Sleep disturbances are common in patients with chronic obstructive pulmonary disease (COPD) with a considerable negative impact on their quality of life. However, factors associated with measures of sleep in daily life have not been investigated before nor has the association between sleep and the ability to engage in physical activity on a day-to-day basis been studied.Aims To provide insight into the relationship between actigraphic sleep measures and disease severity, exertional dyspnoea, gender and parts of the week; and to investigate the association between sleep measures and next day physical activity.Methods Data were analysed from 932 patients with COPD (66% male, 66.4 +/- 8.3 years, FEV1% predicted= 50.8 +/- 20.5). Participants had sleep and physical activity continuously monitored using a multisensor activity monitor for a median of 6 days. Linear mixed effects models were applied to investigate the factors associated with sleep impairment and the association between nocturnal sleep and patients' subsequent daytime physical activity.Results Actigraphic estimates of sleep impairment were greater in patients with worse airflow limitation and worse exertional dyspnoea. Patients with better sleep measures (ie, non-fragmented sleep, sleeping bouts >= 225 min, sleep efficiency >= 91% and time spent awake after sleep onset <57 min) spent significantly more time in light (p<0.01) and moderate-to-vigorous physical activity (p<0.01).Conclusions There is a relationship between measures of sleep in patients with COPD and the amount of activity they undertake during the waking day. Identifying groups with specific sleep characteristics may be useful information when designing physical activity-enhancing interventions.
AB - Background Sleep disturbances are common in patients with chronic obstructive pulmonary disease (COPD) with a considerable negative impact on their quality of life. However, factors associated with measures of sleep in daily life have not been investigated before nor has the association between sleep and the ability to engage in physical activity on a day-to-day basis been studied.Aims To provide insight into the relationship between actigraphic sleep measures and disease severity, exertional dyspnoea, gender and parts of the week; and to investigate the association between sleep measures and next day physical activity.Methods Data were analysed from 932 patients with COPD (66% male, 66.4 +/- 8.3 years, FEV1% predicted= 50.8 +/- 20.5). Participants had sleep and physical activity continuously monitored using a multisensor activity monitor for a median of 6 days. Linear mixed effects models were applied to investigate the factors associated with sleep impairment and the association between nocturnal sleep and patients' subsequent daytime physical activity.Results Actigraphic estimates of sleep impairment were greater in patients with worse airflow limitation and worse exertional dyspnoea. Patients with better sleep measures (ie, non-fragmented sleep, sleeping bouts >= 225 min, sleep efficiency >= 91% and time spent awake after sleep onset <57 min) spent significantly more time in light (p<0.01) and moderate-to-vigorous physical activity (p<0.01).Conclusions There is a relationship between measures of sleep in patients with COPD and the amount of activity they undertake during the waking day. Identifying groups with specific sleep characteristics may be useful information when designing physical activity-enhancing interventions.
KW - OBSTRUCTIVE PULMONARY-DISEASE
KW - QUALITY-OF-LIFE
KW - RESPIRATORY SYMPTOMS
KW - FORGOTTEN DIMENSION
KW - OLDER-ADULTS
KW - INSOMNIA
KW - EXERCISE
KW - REHABILITATION
KW - MEDICINE
KW - VALIDITY
U2 - 10.1136/thoraxjnl-2016-208900
DO - 10.1136/thoraxjnl-2016-208900
M3 - Article
C2 - 28082529
SN - 0040-6376
VL - 72
SP - 694
EP - 701
JO - Thorax
JF - Thorax
IS - 8
ER -