1.19 Calcium Phosphate Ceramics With Inorganic Additives ☆

The use of inorganic compounds as synthetic growth factors is a promising approach for improving the biological properties of existing synthetic bone graft substitutes such as calcium phosphates. In this article we have described some of the inorganic additives that may improve the capabilities of calcium phosphates, and help bridge the gap toward autograft?s performance known as gold standard for bone regeneration. This article focuses on the specific roles of bioinorganics in processes related to bone formation and resorption and how these modify the biological properties of calcium phosphates, and finally provides insight into the future of this field.