
Researcher
Schotten, U.
Full professor - Personal chair
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- 2019
- PublishedLinz, D., Elliott, A. D., Hohl, M., Malik, V., Schotten, U., Dobrev, D., ... Sanders, P. (2019). Role of autonomic nervous system in atrial fibrillation. International Journal of Cardiology, 287, 181-188. https://doi.org/10.1016/j.ijcard.2018.11.091
- PublishedChua, W., Easter, C. L., Guasch, E., Sitch, A., Casadei, B., Crijns, H. J. G. M., ... Fabritz, L. (2019). Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset. BMC Cardiovascular disorders, 19, [120]. https://doi.org/10.1186/s12872-019-1105-4
- PublishedConte, G., Schotten, U., & Auricchio, A. (2019). The Atrial Phenotype of the Inherited Primary Arrhythmia Syndromes. Arrhythmia & Electrophysiology Review, 8(1), 42-46. https://doi.org/10.15420/aer.2019.4.2
- 2018
- PublishedGharaviri, A., Verheule, S., Eckstein, J., Potse, M., Krause, R., Auricchio, A., ... Schotten, U. (2018). Effect of Na+-channel blockade on the three-dimensional substrate of atrial fibrillation in a model of endo-epicardial dissociation and transmural conduction. EP Europace, 20(Suppl. 3), iii69-iii76. https://doi.org/10.1093/europace/euy236
- PublishedPezzuto, S., Gharaviri, A., Schotten, U., Potse, M., Conte, G., Caputo, M. L., ... Auricchio, A. (2018). Beat-to-beat P-wave morphological variability in patients with paroxysmal atrial fibrillation: an in silico study. EP Europace, 20, 26-35. https://doi.org/10.1093/europace/euy227
- PublishedPodziemski, P., Zeemering, S., Kuklik, P., van Hunnik, A., Maesen, B., Maessen, J., ... Schotten, U. (2018). Rotors Detected by Phase Analysis of Filtered, Epicardial Atrial Fibrillation Electrograms Colocalize With Regions of Conduction Block. Circulation-Arrhythmia and Electrophysiology, 11(10), [e005858]. https://doi.org/10.1161/CIRCEP.117.005858
- Published
- PublishedManninger, M., Zweiker, D., van Hunnik, A., Alogna, A., Prassl, A. J., Schipke, J., ... Scherr, D. (2018). Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation. Heart Rhythm, 15(9), 1328-1336. https://doi.org/10.1016/j.hrthm.2018.05.016
- PublishedKirchhof, P., Haeusler, K. G., Blank, B., De Bono, J., Callans, D., Elvan, A., ... Di Biase, L. (2018). Apixaban in patients at risk of stroke undergoing atrial fibrillation ablation. European Heart Journal, 39(32), 2942-2955. https://doi.org/10.1093/eurheartj/ehy176
- Publishedvan Hunnik, A., Zeemering, S., Podziemski, P., Simons, J., Gatta, G., Hannink, L., ... Schotten, U. (2018). Stationary Atrial Fibrillation Properties in the Goat Do Not Entail Stable or Recurrent Conduction Patterns. Frontiers in physiology, 9, [947]. https://doi.org/10.3389/fphys.2018.00947
- PublishedZeemering, S., Lankveld, T. A. R., Bonizzi, P., Limantoro, I., Bekkers, S. C. A. M., Crijns, H. J. G. M., & Schotten, U. (2018). The electrocardiogram as a predictor of successful pharmacological cardioversion and progression of atrial fibrillation. EP Europace, 20(7), E96-E104. https://doi.org/10.1093/europace/eux234
- PublishedErkuner, O., Rienstra, M., Van Gelder, I. C., Schotten, U., Crijns, H. J. G. M., & Luermans, J. G. L. M. (2018). Stroke risk in patients with device-detected atrial high-rate episodes. Netherlands Heart Journal, 26(4), 177-181. https://doi.org/10.1007/s12471-017-1047-3
- PublishedKotecha, D., Breithardt, G., Camm, A. J., Lip, G. Y. H., Schotten, U., Ahlsson, A., ... Kirchhof, P. (2018). Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference. EP Europace, 20(3), 395-407. https://doi.org/10.1093/europace/eux318
- Published
- PublishedConte, G., Caputo, M. L., Volders, P. G. A., Luca, A., Mainardi, L., Schotten, U., ... Auricchio, A. (2018). Concealed abnormal atrial phenotype in patients with Brugada syndrome and no history of atrial fibrillation. International Journal of Cardiology, 253, 66-70. https://doi.org/10.1016/j.ijcard.2017.09.214
- PublishedEuropean Society Cardiology ESC; CATCH ME Consortium; EHRA, Kotecha, D., Chua, W. W. L., Fabritz, L., Hendriks, J., Casadei, B., ... Kirchhof, P. (2018). European Society of Cardiology smartphone and tablet applications for patients with atrial fibrillation and their health care providers. EP Europace, 20(2), 225-233. https://doi.org/10.1093/europace/eux299
- Publishedvan Hunnik, A., Nasrallah, H., Lau, D. H., Kuiper, M., Verheule, S., & Schotten, U. (2018). Vernakalant does not alter early repolarization or contractility in normal and electrically remodelled atria. EP Europace, 20(1), 140-148. https://doi.org/10.1093/europace/eux025
- 2017
- PublishedBonizzi, P., Zeemering, S., Karel, J., azman, M. H., Lankveld, T. A. R., Schotten, U., ... Meste, O. (2017). Noninvasive Characterisation of Short-and Long-Term Recurrence of Atrial Signals During Persistent Atrial Fibrillation. In Computing in Cardiology Rennes, France.
- PublishedHohl, M., Lau, D. H., Mueller, A., Elliott, A. D., Linz, B., Mahajan, R., ... Linz, D. (2017). Concomitant Obesity and Metabolic Syndrome Add to the Atrial Arrhythmogenic Phenotype in Male Hypertensive Rats. Journal of the American Heart Association, 6(9), [006717]. https://doi.org/10.1161/JAHA.117.006717
- PublishedLau, D. H., Linz, D., Schotten, U., Mahajan, R., Sanders, P., & Kalman, J. M. (2017). Pathophysiology of Paroxysmal and Persistent Atrial Fibrillation: Rotors, Foci and Fibrosis. Heart Lung and Circulation, 26(9), 887-893. https://doi.org/10.1016/j.hlc.2017.05.119
- PublishedGharaviri, A., Verheule, S., Eckstein, J., Potse, M., Kuklik, P., Kuijpers, N. H. L., & Schotten, U. (2017). How disruption of endo-epicardial electrical connections enhances endo-epicardial conduction during atrial fibrillation. EP Europace, 19(2), 308-318. https://doi.org/10.1093/europace/euv445
- PublishedKuklik, P., Zeemering, S., van Hunnik, A., Maesen, B., Pison, L., Lau, D. H., ... Schotten, U. (2017). Identification of Rotors during Human Atrial Fibrillation Using Contact Mapping and Phase Singularity Detection: Technical Considerations. Ieee Transactions on Biomedical Engineering, 64(2), 310-318. https://doi.org/10.1109/TBME.2016.2554660
- PublishedSpronk, H. M. H., De Jong, A. M., Verheule, S., De Boer, H. C., Maass, A. H., Lau, D. H., ... Schotten, U. (2017). Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation. European Heart Journal, 38(1), 38-50. https://doi.org/10.1093/eurheartj/ehw119
- PublishedKirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., ... European Stroke Org (2017). Guía ESC 2016 sobre el diagnóstico y tratamiento de la fibrilación auricular, desarrollada en colaboración con la EACTS. Revista Espanola de Cardiologia, 70(1), 50.E1-50.E84. https://doi.org/10.1016/j.recesp.2016.11.014
- PublishedDi Biase, L., Callans, D., Haeusler, K. G., Hindricks, G., Al-Khalidi, H., Mont, L., ... Kirchhof, P. (2017). Rationale and design of AXAFA-AFNET 5: an investigator-initiated, randomized, open, blinded outcome assessment, multi-centre trial to comparing continuous apixaban to vitamin K antagonists in patients undergoing atrial fibrillation catheter ablation. EP Europace, 19(1), 132-138. https://doi.org/10.1093/europace/euw368
- 2016
- PublishedKirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., ... Zeppenfeld, K. (2016). 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. EP Europace, 18(11), 1609-1678. https://doi.org/10.1093/europace/euw295
- PublishedKirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., ... Vardas, P. (2016). 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European Journal of Cardio-Thoracic Surgery, 50(5), E1-E88. https://doi.org/10.1093/ejcts/ezw313
- PublishedKuklik, P., Schaeffer, B., Hoffmann, B. A., Ganesan, A. N., Schreiber, D., Moser, J. M., ... Willems, S. (2016). Local Electrical Dyssynchrony during Atrial Fibrillation: Theoretical Considerations and Initial Catheter Ablation Results. PLOS ONE, 11(10), [e0164236]. https://doi.org/10.1371/journal.pone.0164236
- PublishedKirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., ... Vardas, P. (2016). 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European Heart Journal, 37(38), 2893-2962. https://doi.org/10.1093/eurheartj/ehw210
- PublishedMeste, O., Zeemering, S., Karel, J., Lankveld, T. A. R., Schotten, U., Crijns, H., ... Bonizzi, P. (2016). Noninvasive Recurrence Quanti cation Analysis Predicts Atrial Fibrillation Recurrence in Persistent Patients Undergoing Electrical Cardioversion. In Computing in Cardiology Vancouver, Canada.
- PublishedLinz, D., Hohl, M., Dhein, S., Ruf, S., Reil, J-C., Kabiri, M., ... Schotten, U. (2016). Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats. Cardiovascular Research, 110(3), 371-380. https://doi.org/10.1093/cvr/cvw071
- PublishedReilly, S. N., Liu, X., Carnicer, R., Recalde, A., Muszkiewicz, A., Jayaram, R., ... Casadei, B. (2016). Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase. Science Translational Medicine, 8(340), [340ra74]. https://doi.org/10.1126/scitranslmed.aac4296
- PublishedLau, D. H., Schotten, U., Mahajan, R., Antic, N. A., Hatem, S. N., Pathak, R. K., ... Sanders, P. (2016). Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications. European Heart Journal, 37(20), 1573-+. https://doi.org/10.1093/eurheartj/ehv375
- PublishedSchotten, U., Dobrev, D., Platonov, P. G., Kottkamp, H., & Hindricks, G. (2016). Current controversies in determining the main mechanisms of atrial fibrillation. Journal of Internal Medicine, 279(5), 428-438. https://doi.org/10.1111/joim.12492
- PublishedLankveld, T., de Vos, C. B., Limantoro, I., Zeemering, S., Dudink, E., Crijns, H. J., & Schotten, U. (2016). Systematic analysis of ECG predictors of sinus rhythm maintenance after electrical cardioversion for persistent atrial fibrillation. Heart Rhythm, 13(5), 1020-1027. https://doi.org/10.1016/j.hrthm.2016.01.004
- PublishedVan Gelder, I. C., Hobbelt, A. H., Marcos, E. G., Schotten, U., Cappato, R., Lewalter, T., ... Boriani, G. (2016). Tailored treatment strategies: a new approach for modern management of atrial fibrillation. Journal of Internal Medicine, 279(5), 457-466. https://doi.org/10.1111/joim.12489
- PublishedOpacic, D., van Bragt, K. A., Nasrallah, H. M., Schotten, U., & Verheule, S. (2016). Atrial metabolism and tissue perfusion as determinants of electrical and structural remodelling in atrial fibrillation. Cardiovascular Research, 109(4), 527-541. https://doi.org/10.1093/cvr/cvw007
- PublishedKirchhof, P., Goette, A., Naebauer, M., & Schotten, U. (2016). 12 Jahre AFNET. Vom Forschungsnetzwerk zur Academic Research Organisation. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz, 59(4), 514-522. https://doi.org/10.1007/s00103-016-2323-x
- Publishedvan Hunnik, A., Lau, D. H., Zeemering, S., Kuiper, M., Verheule, S., & Schotten, U. (2016). Antiarrhythmic effect of vernakalant in electrically remodeled goat atria is caused by slowing of conduction and prolongation of postrepolarization refractoriness. Heart Rhythm, 13(4), 964-972. https://doi.org/10.1016/j.hrthm.2015.12.009
- PublishedFabritz, L., Guasch, E., Antoniades, C., Bardinet, I., Benninger, G., Betts, T. R., ... Kirchhof, P. (2016). Expert consensus document: Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment. Nature Reviews Cardiology, 13(4), 230-237. https://doi.org/10.1038/nrcardio.2015.194
- PublishedLankveld, T., Zeemering, S., Scherr, D., Kuklik, P., Hoffmann, B. A., Willems, S., ... Schotten, U. (2016). Atrial Fibrillation Complexity Parameters Derived From Surface ECGs Predict Procedural Outcome and Long-Term Follow-Up of Stepwise Catheter Ablation for Atrial Fibrillation. Circulation-Arrhythmia and Electrophysiology, 9(2), [e003354]. https://doi.org/10.1161/CIRCEP.115.003354
- PublishedKirchhof, P., Breithardt, G., Bax, J., Benninger, G., Blomstrom-Lundqvist, C., Boriani, G., ... Camm, A. J. (2016). A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference. EP Europace, 18(1), 37-50. https://doi.org/10.1093/europace/euv304
- Published
- 2015
- PublishedSchotten, U., Hatem, S., Ravens, U., Jais, P., Mueller, F-U., Goette, A., ... Camm, A. J. (2015). The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results. EP Europace, 17(10), 1457-1466. https://doi.org/10.1093/europace/euv252
- PublishedZeemering, S., Podziemski, P., van Hunnik, A., Maesen, B., Bonizzi, P., & Schotten, U. (2015). Electrogram Coupling as a Measure of Local Conduction during Atrial Fibrillation. In Computing in Cardiology Nice, France.
- PublishedPodziemski, P., Kuklik, P., van Hunnik, A., Zeemering, S., Maesen, B., & Schotten, U. (2015). Far-field effect in unipolar electrograms revisited: High-density mapping of atrial fibrillation in humans. IEEE Engineering in Medicine and Biology Society, 2015, 5680-3. https://doi.org/10.1109/EMBC.2015.7319681
- PublishedLau, D. H., Maesen, B., Zeemering, S., Kuklik, P., van Hunnik, A., Lankveld, T. A. R., ... Schotten, U. (2015). Indices of bipolar complex fractionated atrial electrograms correlate poorly with each other and atrial fibrillation substrate complexity. Heart Rhythm, 12(7), 1415-1423. https://doi.org/10.1016/j.hrthm.2015.03.017
- PublishedLau, D. H., Volders, P. G. A., Kohl, P., Prinzen, F. W., Zaza, A., Kaeaeb, S., ... Schotten, U. (2015). Opportunities and challenges of current electrophysiology research: a plea to establish 'translational electrophysiology' curricula. EP Europace, 17(5), 825-833. https://doi.org/10.1093/europace/euu301
- Publishedvan Bragt, K. A., Nasrallah, H. M., Kuiper, M., van Hunnik, A., Kuijpers, N. H. L., Schotten, U., & Verheule, S. (2015). Dynamic regulation of atrial coronary blood flow in healthy adult pigs. Heart Rhythm, 12(5), 991-1000. https://doi.org/10.1016/j.hrthm.2015.01.016
- PublishedPluteanu, F., Hess, J., Plackic, J., Nikonova, Y., Preisenberger, J., Bukowska, A., ... Kockskaemper, J. (2015). Early subcellular Ca2+ remodelling and increased propensity for Ca2+ alternans in left atrial myocytes from hypertensive rats. Cardiovascular Research, 106(1), 87-97. https://doi.org/10.1093/cvr/cvv045