Klaus-Peter Lesch

Research output

Research output per year 2011 2013 2014 2015 2017 2019 2020 2021 2024

• 182 Article
• 8 (Systematic) Review article
• 3 Erratum / corrigendum / retractions
• 1 Editorial

Research output per year

Research output per year

Search results

• 2024

  MAOA methylation is associated with impulsive and antisocial behaviour: dependence on allelic variation, family environment and diet

  Kanarik, M., Sakala, K., Matrov, D., Kaart, T., Roy, A., Ziegler, G. C., Veidebaum, T., Lesch, K-P. & Harro, J., Jan 2024, In: Journal of Neural Transmission. 131, 1, p. 59-71 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review
• 2023

  Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains: (Nature Genetics, (2023), 55, 2, (198-208), 10.1038/s41588-022-01285-8)

  Demontis, D., Walters, G. B., Athanasiadis, G., Walters, R., Therrien, K., Nielsen, T. T., Farajzadeh, L., Voloudakis, G., Bendl, J., Zeng, B., Zhang, W., Grove, J., Als, T. D., Duan, J., Satterstrom, F. K., Bybjerg-Grauholm, J., Bækved-Hansen, M., Gudmundsson, O. O., Magnusson, S. H., Baldursson, G., & 33 othersDavidsdottir, K., Haraldsdottir, G. S., Agerbo, E., Hoffman, G. E., Dalsgaard, S., Martin, J., Ribasés, M., Boomsma, D. I., Soler Artigas, M., Roth Mota, N., Howrigan, D., Medland, S. E., Zayats, T., Rajagopal, V. M., Havdahl, A., Doyle, A., Reif, A., Thapar, A., Cormand, B., Liao, C., Burton, C., Bau, C. H. D., Rovaris, D. L., Sonuga-Barke, E., Corfield, E., Grevet, E. H., Larsson, H., Gizer, I. R., Waldman, I., Lesch, K. P., Borglum, A., ADHD Working Group of the Psychiatric Genomics Consortium & iPSYCH-Broad Consortium, 1 Apr 2023, In: Nature Genetics. 55, 4, p. 730 1 p.

  Research output: Contribution to journal › Erratum / corrigendum / retractions › Academic

  Open Access

• Generation of a ST3GAL3 null mutant induced pluripotent stem cell (iPSC) line (UKWMPi002-A-3) by CRISPR/Cas9 genome editing

  Diouf, D., Vitale, M. R., Zoller, J. E. M., Pineau, A. M., Klopocki, E., Hamann, C., Ziegler, G. C., Vanmierlo, T., Van den Hove, D. & Lesch, K. P., 1 Mar 2023, In: Stem Cell Research. 67, 1, 6 p., 103038.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

  Demontis, D., Walters, G. B., Athanasiadis, G., Walters, R., Therrien, K., Nielsen, T. T., Farajzadeh, L., Voloudakis, G., Bendl, J., Zeng, B., Zhang, W., Grove, J., Als, T. D., Duan, J., Satterstrom, F. K., Bybjerg-Grauholm, J., Bækved-Hansen, M., Gudmundsson, O. O., Magnusson, S. H., Baldursson, G., & 33 othersDavidsdottir, K., Haraldsdottir, G. S., Agerbo, E., Hoffman, G. E., Dalsgaard, S., Martin, J., Ribasés, M., Boomsma, D. I., Soler Artigas, M., Roth Mota, N., Howrigan, D., Medland, S. E., Zayats, T., Rajagopal, V. M., Havdahl, A., Doyle, A., Reif, A., Thapar, A., Cormand, B., Liao, C., Burton, C., Bau, C. H. D., Rovaris, D. L., Sonuga-Barke, E., Corfield, E., Grevet, E. H., Larsson, H., Gizer, I. R., Waldman, I., Lesch, K. P., Borglum, A. D., ADHD Working Group of the Psychiatric Genomics Consortium & iPSYCH-Broad Consortium, 1 Feb 2023, In: Nature Genetics. 55, 2, p. 198-208 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genome-wide DNA methylation analysis of aggressive behaviour: a longitudinal population-based study

  Pishva, E., van den Hove, D. L. A., Laroche, V., Lvovs, A., Roy, A., Ortega, G., Burrage, J., Veidebaum, T., Kanarik, M., Mill, J., Lesch, K. P. & Harro, J., Jul 2023, In: Journal of Child Psychology and Psychiatry. 64, 7, p. 998-1006 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Lipopolysaccharide triggers exacerbated microglial activation, excessive cytokine release and behavioural disturbances in mice with truncated Fused-in-Sarcoma Protein (FUS)

  Trofimov, A., Pavlov, D., Goswami, A., Gorlova, A., Chaprov, K., Umriukhin, A., Kalueff, A., Deykin, A., Lesch, K. P., Anthony, D. C. & Strekalova, T., 1 Nov 2023, In: Brain, Behavior, & Immunity - Health. 33, 1, 7 p., 100686.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Molecular signature of excessive female aggression: study of stressed mice with genetic inactivation of neuronal serotonin synthesis

  Strekalova, T., Moskvin, O., Jain, A. Y., Gorbunov, N., Gorlova, A., Sadovnik, D., Umriukhin, A., Cespuglio, R., Yu, W. S., Tse, A. C. K., Kalueff, A. V., Lesch, K-P. & Lim, L. W., 1 Aug 2023, In: Journal of Neural Transmission. 130, 9, p. 1113-1132 20 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Serotonergic modulation of normal and abnormal brain dynamics: The genetic influence of the TPH2 G-703T genotype and DNA methylation on wavelet variance in children and adolescents with and without ADHD

  Akhrif, A., Romanos, M., Peters, K., Furtmann, A-K., Caspers, J., Lesch, K-P., Meisenzahl-Lechner, E. M. & Neufang, S., 27 Apr 2023, In: PLOS ONE. 18, 4, 20 p., e0282813.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Serotonin Transporter (SERT) Expression Modulates the Composition of the Western-Diet-Induced Microbiota in Aged Female Mice

  Bloemendaal, M., Veniaminova, E., Anthony, D. C., Gorlova, A., Vlaming, P., Khairetdinova, A., Cespuglio, R., Lesch, K. P., Vasquez, A. A. & Strekalova, T., 1 Jul 2023, In: Nutrients. 15, 13, 19 p., 3048.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The long and the short of it: 5-HTTLPR and moral judgement

  Armbruster, D., Lesch, K-P. & Strobel, A., 24 Aug 2023, In: Behavioural Brain Research. 452, 1, 7 p., 114524.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The Translational Genetics of Adhd and Related Phenotypes in Model Organisms

  Cabana-Domínguez, J., Antón-Galindo, E., Fernàndez-Castillo, N., Singgih, E. L., O'Leary, A., Norton, W. H., Strekalova, T., Schenck, A., Reif, A., Lesch, K-P., Slattery, D. & Cormand, B., Jan 2023, In: Neuroscience and Biobehavioral Reviews. 144, 1, 32 p., 104949.

  Research output: Contribution to journal › (Systematic) Review article › peer-review

  Open Access

• Understanding the Role of Oxidative Stress, Neuroinflammation and Abnormal Myelination in Excessive Aggression Associated with Depression: Recent Input from Mechanistic Studies

  Gorlova, A., Svirin, E., Pavlov, D., Cespuglio, R., Proshin, A., Schroeter, C. A., Lesch, K. P. & Strekalova, T., 1 Jan 2023, In: International Journal of Molecular Sciences. 24, 2, 29 p., 915.

  Research output: Contribution to journal › (Systematic) Review article › peer-review

  Open Access
• 2022

  Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks

  Mossink, B., Van Rhijn, J-R., Wang, S., Linda, K., Vitale, M. R., Zoller, J. E. M., van Hugte, E. J. H., Bak, J., Verboven, A. H. A., Selten, M., Negwer, M., Latour, B. L., van der Werf, I., Keller, J. M., Gunnewiek, T. M. K., Schoenmaker, C., Oudakker, A., Anania, A., Jansen, S., Lesch, K-P., & 4 othersFrega, M., van Bokhoven, H., Schubert, D. & Kasri, N. N., Jan 2022, In: Molecular Psychiatry. 27, 1, p. 1-18 18 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives

  Strekalova, T., Liu, Y. Z., Kiselev, D., Khairuddin, S., Chiu, J. L. Y., Lam, J., Chan, Y. S., Pavlov, D., Proshin, A., Lesch, K. P., Anthony, D. C. & Lim, L. W., Mar 2022, In: Psychopharmacology. 239, 3, p. 663-693 31 p.

  Research output: Contribution to journal › (Systematic) Review article › peer-review

  Open Access

• Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

  Hoogman, M., van Rooij, D., Klein, M., Boedhoe, P., Ilioska, I., Li, T., Patel, Y., Postema, M. C., Zhang-James, Y., Anagnostou, E., Arango, C., Auzias, G., Banaschewski, T., Bau, C. H. D., Behrmann, M., Bellgrove, M. A., Brandeis, D., Brem, S., Busatto, G. F., Calderoni, S., & 60 othersCalvo, R., Castellanos, F. X., Coghill, D., Conzelmann, A., Daly, E., Deruelle, C., Dinstein, I., Durston, S., Ecker, C., Ehrlich, S., Epstein, J. N., Fair, D. A., Fitzgerald, J., Freitag, C. M., Frodl, T., Gallagher, L., Grevet, E. H., Haavik, J., Hoekstra, P. J., Janssen, J., Karkashadze, G., King, J. A., Konrad, K., Kuntsi, J., Lazaro, L., Lerch, J. P., Lesch, K-P., Louza, M. R., Luna, B., Mattos, P., McGrath, J., Muratori, F., Murphy, C., Nigg, J. T., Oberwelland-Weiss, E., Tuura, R. L. OG., O'Hearn, K., Oosterlaan, J., Parellada, M., Pauli, P., Plessen, K. J., Ramos-Quiroga, J. A., Reif, A., Reneman, L., Retico, A., Rosa, P. G. P., Rubia, K., Shaw, P., Silk, T. J., Tamm, L., Vilarroya, O., Walitza, S., Jahanshad, N., Faraone, S., Francks, C., van den Heuvel, O. A., Paus, T., Thompson, P. M., Buitelaar, J. K. & Franke, B., Jan 2022, In: Human Brain Mapping. 43, 1, p. 37-55 19 p.

  Research output: Contribution to journal › (Systematic) Review article › peer-review

  Open Access

• Exploring the Contribution to ADHD of Genes Involved in Mendelian Disorders Presenting with Hyperactivity and/or Inattention

  Fernàndez-Castillo, N., Cabana-Domínguez, J., Kappel, D. B., Torrico, B., Weber, H., Lesch, K-P., Lao, O., Reif, A. & Cormand, B., Jan 2022, In: Genes. 13, 1, 12 p., 93.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis

  Grotzinger, A. D., Mallard, T. T., Akingbuwa, W. A., Ip, H. F., Adams, M. J., Lewis, C. M., McIntosh, A. M., Grove, J., Dalsgaard, S., Lesch, K-P., Strom, N., Meier, S. M., Mattheisen, M., Borglum, A. D., Mors, O., Breen, G., Lee, P. H., Kendler, K. S., Smoller, J. W., Tucker-Drob, E. M., & 5 othersNivard, M. G., Tourette Syndrome and Obsessive Compulsive Disorder Working Group of the Psychiatric Genetics Consortium, Bipolar Disorder Working Group of the Psychiatric Genetics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genetics Consortium & Schizophrenia Working Group of the Psychiatric Genetics Consortium, May 2022, In: Nature Genetics. 54, 5, p. 548-559 18 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Hippocampal Over-Expression of Cyclooxygenase-2 (COX-2) Is Associated with Susceptibility to Stress-Induced Anhedonia in Mice

  Strekalova, T., Pavlov, D., Trofimov, A., Anthony, D. C., Svistunov, A., Proshin, A., Umriukhin, A., Lyundup, A., Lesch, K-P. & Cespuglio, R., 13 Feb 2022, In: International journal of molecular sciences. 23, 4, 22 p., 2061.

  Research output: Contribution to journal › Article › Academic

  Open Access

• Immunomodulatory effects of new phytotherapy on human macrophages and TLR4- and TLR7/8-mediated viral-like inflammation in mice

  Schapovalova, O., Gorlova, A., de Munter, J., Sheveleva, E., Eropkin, M., Gorbunov, N., Sicker, M., Umriukhin, A., Lyubchyk, S., Lesch, K-P., Strekalova, T. & Schroeter, C. A., 22 Aug 2022, In: Frontiers in medicine. 9, 14 p., 952977.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Predation Stress Causes Excessive Aggression in Female Mice with Partial Genetic Inactivation of Tryptophan Hydroxylase-2: Evidence for Altered Myelination-Related Processes

  Svirin, E., Veniaminova, E., Costa-Nunes, J. P., Gorlova, A., Umriukhin, A., Kalueff, A. V., Proshin, A., Anthony, D. C., Nedorubov, A., Tse, A. C. K., Walitza, S., Lim, L. W., Lesch, K-P. & Strekalova, T., 18 Mar 2022, In: Cells. 11, 6, 22 p., 1036.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p

  Weiner, D. J., Ling, E., Erdin, S., Tai, D. J. C., Yadav, R., Grove, J., Fu, J. M., Nadig, A., Carey, C. E., Baya, N., Bybjerg-Grauholm, J., Mortensen, P. B., Werge, T., Demontis, D., Mors, O., Nordentoft, M., Als, T. D., Baekvad-Hansen, M., Rosengren, A., Havdahl, A., & 33 othersHedemand, A., Palotie, A., Chakravarti, A., Arking, D., Sulovari, A., Starnawska, A., Thiruvahindrapuram, B., de Leeuw, C., Carey, C., Ladd-Acosta, C., van der Merwe, C., Devlin, B., Cook, E. H., Eichler, E., Corfield, E., Dieleman, G., Schellenberg, G., Hakonarson, H., Coon, H., Dziobek, I., Vorstman, J., Girault, J., Sutcliffe, J. S., Duan, J., Nurnberger, J., Hallmayer, J., Buxbaum, J., Piven, J., Weiss, L., Lesch, K. P., ADHD Working Group of the Psychiatric Genomics Consortium, ASD Working Group of the Psychiatric Genomics Consortium & iPSYCH Consortium, 1 Nov 2022, In: Nature Genetics. 54, 11, p. 1630-1639 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer's Disease

  von Linstow, C. U., Waider, J., Bergh, M. S-S., Anzalone, M., Madsen, C., Nicolau, A. B., Wirenfeldt, M., Lesch, K-P. & Finsen, B., 2022, In: Journal of Alzheimer's Disease. 85, 3, p. 1283-1300 18 p.

  Research output: Contribution to journal › Article › Academic › peer-review
• 2021

  5-HTT Deficiency in Male Mice Affects Healing and Behavior after Myocardial Infarction

  Popp, S., Schmitt-Bohrer, A., Langer, S., Hofmann, U., Hommers, L., Schuh, K., Frantz, S., Lesch, K. P. & Frey, A., 1 Jul 2021, In: Journal of Clinical Medicine. 10, 14, 23 p., 3104.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• A Common CDH13 Variant Is Associated with Low Agreeableness and Neural Responses to Working Memory Tasks in ADHD

  Ziegler, G. C., Ehlis, A. C., Weber, H., Vitale, M. R., Zoller, J. E. M., Ku, H. P., Schiele, M. A., Kurbitz, L. I., Romanos, M., Pauli, P., Kalisch, R., Zwanzger, P., Domschke, K., Fallgatter, A. J., Reif, A. & Lesch, K. P., 1 Sept 2021, In: Genes. 12, 9, 14 p., 1356.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Altered behaviour, dopamine and norepinephrine regulation in stressed mice heterozygous in TPH2 gene

  Strekalova, T., Svirin, E., Waider, J., Gorlova, A., Cespuglio, R., Kalueff, A., Pomytkin, I., Schmitt-Boehrer, A. G., Lesch, K. P. & Anthony, D. C., 8 Jun 2021, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 108, 12 p., 110155.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• ASD-like behaviors, a dysregulated inflammatory response and decreased expression of PLP1 characterize mice deficient for sialyltransferase ST3GAL5

  Strekalova, T., Svirin, E., Veniaminova, E., Kopeikina, E., Veremeyko, T., Yung, A. W. Y., Proshin, A., Walitza, S., Anthony, D. C., Lim, L. W., Lesch, K-P. & Ponomarev, E. D., Oct 2021, In: Brain, Behavior, & Immunity - Health. 16, 8 p., 100306.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

  Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasés, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M., Mors, O., Mortensen, P. B., Andreassen, O. A., Arranz, M. J., Banaschewski, T., Bau, C., Bellgrove, M., Biederman, J., & 31 othersBrikell, I., Buitelaar, J. K., Burton, C. L., Casas, M., Crosbie, J., Doyle, A. E., Ebstein, R. P., Elia, J., Elizabeth, C. C., Grevet, E., Grizenko, N., Havdahl, A., Hawi, Z., Hebebrand, J., Hervas, A., Hohmann, S., Haavik, J., Joober, R., Kent, L., Kuntsi, J., Langley, K., Larsson, H., Lesch, K. P., Leung, P. W. L., Liao, C., Loo, S. K., Martin, J., Martin, N. G., Medland, S. E., Miranda, A. & ADHD Working Group of the Psychiatric Genomics Consortium, 15 Feb 2021, In: Nature Communications. 12, 1, 1 p., 1166.

  Research output: Contribution to journal › Erratum / corrigendum / retractions › Academic

  Open Access

• Dorsal raphe serotonin neurotransmission is required for the expression of nursing behavior and for pup survival

  Muzerelle, A., Soiza-Reilly, M., Hainer, C., Ruet, P. L., Lesch, K. P., Bader, M., Alenina, N., Scotto-Lomassese, S. & Gaspar, P., 16 Mar 2021, In: Scientific Reports. 11, 1, 14 p., 6004.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis

  Zhang-James, Y., Helminen, E. C., Liu, J., Busatto, G. F., Calvo, A., Cercignani, M., Chaim-Avancini, T. M., Gabel, M. C., Harrison, N. A., Lazaro, L., Lera-Miguel, S., Louza, M. R., Nicolau, R., Rosa, P. G. P., Schulte-Rutte, M., Zanetti, M. V., Ambrosino, S., Asherson, P., Banaschewski, T., Baranov, A., & 32 othersBaumeister, S., Baur-Streubel, R., Bellgrove, M. A., Biederman, J., Bralten, J., Bramati, I. E., Brandeis, D., Brem, S., Buitelaar, J. K., Castellanos, F. X., Chantiluke, K. C., Christakou, A., Coghill, D., Conzelmann, A., Cubillo, A. I., Dale, A. M., de Zeeuw, P., Doyle, A. E., Durston, S., Earl, E. A., Epstein, J. N., Ethofer, T., Fair, D. A., Fallgatter, A. J., Frodl, T., Gogberashvili, T., Haavik, J., Hartman, C. A., Heslenfeld, D. J., Lesch, K. P., ENIGMA-ADHD Working Group & Faraone, S. V., 1 Feb 2021, In: Translational Psychiatry. 11, 1, 9 p., 82.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Generation of induced pluripotent stem cell (iPSC) lines carrying a heterozygous (UKWMPi002-A-1) and null mutant knockout (UKWMPi002-A-2) of Cadherin 13 associated with neurodevelopmental disorders using CRISPR/Cas9

  Vitale, M. R., Zoeller, J. E. M., Jansch, C., Janz, A., Edenhofer, F., Klopocki, E., van den Hove, D., Vanmierlo, T., Rivero, O., Kasri, N. N., Ziegler, G. C. & Lesch, K-P., Mar 2021, In: Stem Cell Research. 51, p. 1-5 5 p., 102169.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Generation of multiple human iPSC lines from peripheral blood mononuclear cells of two SLC2A3 deletion and two SLC2A3 duplication carriers

  Ziegler, G. C., Radtke, F., Vitale, M. R., Preusse, A., Klopocki, E., Herms, S. & Lesch, K. P., 1 Oct 2021, In: Stem Cell Research. 56, 5 p., 102526.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Haploinsufficiency of the Attention-Deficit/Hyperactivity Disorder Risk Gene St3gal3 in Mice Causes Alterations in Cognition and Expression of Genes Involved in Myelination and Sialylation

  Rivero, O., Alhama-Riba, J., Ku, H. P., Fischer, M., Ortega, G., Almos, P., Diouf, D., van den Hove, D. & Lesch, K. P., 28 Sept 2021, In: Frontiers in Genetics. 12, 16 p., 688488.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish-implications for neurodevelopmental disorders

  Luffe, T. M., D'Orazio, A., Bauer, M., Gioga, Z., Schoeffler, V., Lesch, K. P., Romanos, M., Drepper, C. & Lillesaar, C., 14 Oct 2021, In: Translational Psychiatry. 11, 1, 12 p., 529.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Increased Oxidative Stress in the Prefrontal Cortex as a Shared Feature of Depressive- and PTSD-Like Syndromes: Effects of a Standardized Herbal Antioxidant

  de Munter, J., Pavlov, D., Gorlova, A., Sicker, M., Proshin, A., Kalueff, A. V., Svistunov, A., Kiselev, D., Nedorubov, A., Morozov, S., Umriukhin, A., Lesch, K. P., Strekalova, T. & Schroeter, C. A., 15 Apr 2021, In: Frontiers in nutrition. 8, 17 p., 661455.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• No links between genetic variation and developing theory of mind: A preregistered replication attempt of candidate gene studies

  Opitz, T., Schuwerk, T., Paulus, M., Kloo, D., Osterhaus, C., Lesch, K. P. & Sodian, B., 1 Sept 2021, In: Developmental Science. 24, 5, 11 p., e13100.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• REVERSE phenotyping-Can the phenotype following constitutive Tph2 gene inactivation in mice be transferred to children and adolescents with and without adhd?

  Akhrif, A., Roy, A., Peters, K., Lesch, K. P., Romanos, M., Schmitt-Bohrer, A. & Neufang, S., May 2021, In: Brain and Behavior. 11, 5, 13 p., e02054.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

  Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasas, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M., Mors, O., Mortensen, P. B., Andreassen, O. A., Arranz, M. J., Banaschewski, T., Bau, C., Bellgrove, M., Biederman, J., & 31 othersBrikell, I., Buitelaar, J. K., Burton, C. L., Casas, M., Crosbie, J., Doyle, A. E., Ebstein, R. P., Elia, J., Elizabeth, C. C., Grevet, E., Grizenko, N., Havdahl, A., Hawi, Z., Hebebrand, J., Hervas, A., Hohmann, S., Haavik, J., Joober, R., Kent, L., Kuntsi, J., Langley, K., Larsson, H., Lesch, K. P., Leung, P. W. L., Liao, C., Loo, S. K., Martin, J., Martin, N. G., Medland, S. E., Miranda, A. & ADHD Working Group of the Psychiatric Genomics Consortium, 1 Dec 2021, In: Nature Communications. 12, 1, 12 p., 576.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Serotonin deficiency induced after brain maturation rescues consequences of early life adversity

  Aboagye, B., Weber, T., Merdian, H. L., Bartsch, D., Lesch, K. P. & Waider, J., 8 Mar 2021, In: Scientific Reports. 11, 1, 13 p., 5368.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly

  Jansch, C., Ziegler, G. C., Forero, A., Gredy, S., Waldchen, S., Vitale, M. R., Svirin, E., Zoller, J. E. M., Waider, J., Gunther, K., Edenhofer, F., Sauer, M., Wischmeyer, E. & Lesch, K. P., 1 Feb 2021, In: Journal of Neural Transmission. 128, 2, p. 225-241 17 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Sex differences in anxiety and depression in children with attention deficit hyperactivity disorder: Investigating genetic liability and comorbidity

  Martin, J., Agha, S. S., Eyre, O., Riglin, L., Langley, K., Hubbard, L., Stergiakouli, E., O'Donovan, M., Thapar, A., Andreassen, O. A., Arnatkeviciute, A., Banaschewski, T., Bellgrove, M., Borglum, A., Buitelaar, J., Burton, C., Charach, A., Corfield, E., Cormand, B., Crosbie, J., & 31 othersDemontis, D., Faraone, S. V., Franke, B., Gizer, I., Grevet, E. H., Haavik, J., Hakonarson, H., Hartman, C., Havdahl, A., Hawi, Z., Hebebrand, J., Hinney, A., Joober, R., Linnér, R. K., Klein, M., Kuntsi, J., Larsson, H., Lesch, K. P., Leung, P. W. L., Liao, C., Loo, S., Medland, S., Philipsen, A., Ramos-Quiroga, J. A., Reichborn-Kjennerud, T., Reif, A., Ribases, M., Salum, G., Schachar, R., Sengupta, S. M. & Psychiatric Genomics Consortium ADHD Working Group, 1 Oct 2021, In: American Journal of Medical Genetics Part B-neuropsychiatric Genetics. 186, 7, p. 412-422 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Sex-Specific ADHD-like Behaviour, Altered Metabolic Functions, and Altered EEG Activity in Sialyltransferase ST3GAL5-Deficient Mice

  Strekalova, T., Veniaminova, E., Svirin, E., Kopeikina, E., Veremeyko, T., Yung, A. W. Y., Proshin, A., Tan, S. Z. K., Khairuddin, S., Lim, L. W., Lesch, K. P., Walitza, S., Anthony, D. C. & Ponomarev, E. D., 1 Dec 2021, In: Biomolecules. 11, 12, 9 p., 1759.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The continued need for animals to advance brain research

  Homberg, J. R., Adan, R. A. H., Alenina, N., Asiminas, A., Bader, M., Beckers, T., Begg, D. P., Blokland, A., Burger, M. E., van Dijk, G., Eisel, U. L. M., Elgersma, Y., Englitz, B., Fernandez-Ruiz, A., Fitzsimons, C. P., van Dam, A-M., Gass, P., Grandjean, J., Havekes, R., Henckens, M. J. A. G., & 54 othersHerden, C., Hut, R. A., Jarrett, W., Jeffrey, K., Jezova, D., Kalsbeek, A., Kamermans, M., Kas, M. J., Kasri, N. N., Kiliaan, A. J., Kolk, S. M., Korosi, A., Korte, S. M., Kozicz, T., Kushner, S. A., Leech, K., Lesch, K-P., Lesscher, H., Lucassen, P. J., Luthi, A., Ma, L., Mallien, A. S., Meerlo, P., Mejias, J. F., Meye, F. J., Mitchell, A. S., Mul, J. D., Olcese, U., González, A. O., Olivier, J. D. A., Pasqualetti, M., Pennartz, C. M. A., Popik, P., Prickaerts, J., de la Prida, L. M., Ribeiro, S., Roozendaal, B., Rossato, J. I., Salari, A-A., Schoemaker, R. G., Smit, A. B., Vanderschuren, L. J. M. J., Takeuchi, T., van der Veen, R., Smidt, M. P., Vyazovskiy, V. V., Wiesmann, M., Wierenga, C. J., Williams, B., Willuhn, I., Wöhr, M., Wolvekamp, M., van der Zee, E. A. & Genzel, L., 4 Aug 2021, In: Neuron. 109, 15, p. 2374-2379 6 p.

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• Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders

  Patel, Y., Parker, N., Shin, J., Howard, D., French, L., Thomopoulos, S. I., Pozzi, E., Abe, Y., Abe, C., Anticevic, A., Alda, M., Aleman, A., Alloza, C., Alonso-Lana, S., Ameis, S. H., Anagnostou, E., McIntosh, A. A., Arango, C., Arnold, P. D., Asherson, P., & 32 othersAssogna, F., Auzias, G., Ayesa-Arriola, R., Bakker, G., Banaj, N., Banaschewski, T., Bandeira, C. E., Baranov, A., Bargallo, N., Bau, C. H. D., Baumeister, S., Baune, B. T., Bellgrove, M. A., Benedetti, F., Bertolino, A., Boedhoe, P. S. W., Boks, M., Bollettini, I., del Mar Bonnin, C., Borgers, T., Borgwardt, S., Brandeis, D., Brennan, B. P., Bruggemann, J. M., Bulow, R., Green, M. J., Lesch, K-P., Seitz, J., van Amelsvoort, T., Yang, T. T., Attention-Deficit/Hyperactivity Disorder Working Group & Paus, T., Jan 2021, In: JAMA Psychiatry. 78, 1, p. 47-63 17 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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• 2020

  Cellular effects and clinical implications of SLC2A3 copy number variation

  Ziegler, G. C., Almos, P., McNeill, R. V., Jansch, C. & Lesch, K-P., Dec 2020, In: Journal of Cellular Physiology. 235, 12, p. 9021-9036 16 p.

  Research output: Contribution to journal › (Systematic) Review article › peer-review

  Open Access

• Cumulative Dopamine Genetic Score predicts behavioral and electrophysiological correlates of response inhibition via interactions with task demand

  Enge, S., Sach, M., Reif, A., Lesch, K-P., Miller, R. & Fleischhauer, M., Feb 2020, In: Cognitive, Affective, & Behavioral Neuroscience. 20, 1, p. 59-75 17 p.

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• Delaying memory decline: different options and emerging solutions

  Schneider, F., Horowitz, A., Lesch, K-P. & Dandekar, T., 21 Jan 2020, In: Translational Psychiatry. 10, 1, 10 p., 13.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• DNA methylation in the 5-HTT regulatory region is associated with CO2-induced fear in panic disorder patients

  Leibold, N. K., Weidner, M. T., Ziegler, C., Ortega, G., Domschke, K., Lesch, K. P., Van den Hove, D. L. & Schruers, K. R., Jul 2020, In: European Neuropsychopharmacology. 36, p. 154-159 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Effect of serotonin transporter genotype on carbon dioxide-induced fear-related behavior in mice

  Leibold, N. K., van den Hove, D. L. A., Weidner, M. T., Buchanan, G. F., Steinbusch, H. W. M., Lesch, K-P. & Schruers, K. R. J., Dec 2020, In: Journal of Psychopharmacology. 34, 12, p. 1408-1417 10 p.

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• Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing

  Corominas, J., Klein, M., Zayats, T., Rivero, O., Ziegler, G. C., Pauper, M., Neveling, K., Poelmans, G., Jansch, C., Svirin, E., Geissler, J., Weber, H., Reif, A., Vasquez, A. A., Galesloot, T. E., Kiemeney, L. A. L. M., Buitelaar, J. K., Ramos-Quiroga, J-A., Cormand, B., Ribases, M., & 10 othersHveem, K., Gabrielsen, M. E., Hoffmann, P., Cichon, S., Haavik, J., Johansson, S., Jacob, C. P., Romanos, M., Franke, B. & Lesch, K-P., Sept 2020, In: Molecular Psychiatry. 25, 9, p. 2047-2057 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• KCNJ6 variants modulate reward-related brain processes and impact executive functions in attention-deficit/hyperactivity disorder

  Ziegler, G. C., Roeser, C., Renner, T., Hahn, T., Ehlis, A-C., Weber, H., Dempfle, A., Walitza, S., Jacob, C., Romanos, M., Fallgatter, A. J., Reif, A. & Lesch, K-P., Jul 2020, In: American Journal of Medical Genetics Part B-neuropsychiatric Genetics. 183, 5, p. 247-257 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review