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Researcher

Ophelders, D.R.M.G.

Researcher

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  1. 2019
  2. Published
    Gussenhoven, R., Klein, L., Ophelders, D. R. M. G., Habets, D. H. J., Giebel, B., Kramer, B. W., ... Wolfs, T. G. A. M. (2019). Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy. Journal of Clinical Medicine, 8(2), [137]. https://doi.org/10.3390/jcm8020137
  3. 2018
  4. Published
    Wahl, H. B., Hutten, M. C., Monz, D., Tutdibi, E., Ophelders, D., Nikiforou, M., ... Kramer, B. W. (2018). Vitamin A Supplementation by Endotracheal Application of a Nano-encapsulated Preparation Is Feasible in Ventilated Preterm Lambs. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 31(6), 323-330. [323-330]. https://doi.org/10.1089/jamp.2017.1438
  5. Published
    Gussenhoven, R., Westerlaken, R. J. J., Ophelders, D. R. M. G., Jobe, A. H., Kemp, M. W., Kallapur, S. G., ... Wolfs, T. G. A. M. (2018). Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus. Journal of Neuroinflammation, 15, [113]. https://doi.org/10.1186/s12974-018-1149-x
  6. Published
    Andriessen, P., Zwanenburg, A., van Laar, J. O. E. H., Vullings, R., Hermans, B. J. M., Niemarkt, H. J., ... Delhaas, T. (2018). ST waveform analysis for monitoring hypoxic distress in fetal sheep after prolonged umbilical cord occlusion. PLOS ONE, 13(4), [e0195978]. https://doi.org/10.1371/journal.pone.0195978
  7. 2017
  8. Published
    Ricci, F., Salomone, F., Kuypers, E., Ophelders, D., Nikiforou, M., Willems, M., ... Bianco, F. (2017). In Vivo Evaluation of the Acute Pulmonary Response to Poractant Alfa and Bovactant Treatments in Lung-Lavaged Adult Rabbits and in Preterm Lambs with Respiratory Distress Syndrome. Frontiers in pediatrics, 5, [186]. https://doi.org/10.3389/fped.2017.00186
  9. Published
    Ophelders, D. R. M. G. (2017). Novel treatment strategies for the protection of the preterm brain: re-balancing inflammation and regeneration. Maastricht: Datawyse / Universitaire Pers Maastricht. https://doi.org/10.26481/dis.20170317do
  10. Published
    Gussenhoven, R., Ophelders, D. R. M. G., Kemp, M. W., Payne, M. S., Spiller, O. B., Beeton, M. L., ... Wolfs, T. G. A. M. (2017). The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development. Developmental Neuroscience, 39(6), 472-486. https://doi.org/10.1159/000479021
  11. 2016
  12. Published
    Zwanenburg, A., Hermans, B. J. M., Andriessen, P., Niemarkt, H. J., Jellema, R. K., Ophelders, D. R. M. G., ... Delhaas, T. (2016). Comparison of ECG-based physiological markers for hypoxia in a preterm ovine model. Pediatric Research, 79(6), 907-915. https://doi.org/10.1038/pr.2016.21
  13. Published
    Ophelders, D. R. M. G., Wolfs, T. G. A. M., Jellema, R. K., Zwanenburg, A., Andriessen, P., Delhaas, T., ... Kramer, B. W. (2016). Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia. Stem Cells Translational Medicine, 5(6), 754-763. https://doi.org/10.5966/sctm.2015-0197
  14. Published
    Caron, M. M. J., Emans, P. J., Sanen, K., Surtel, D., Cremers, A., Ophelders, D., ... Welting, T. J. M. (2016). The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells. PLOS ONE, 11(4), [e0153162]. https://doi.org/10.1371/journal.pone.0153162
  15. Published
    Ophelders, D. R. M. G., Gussenhoven, R., Lammens, M., Kusters, B., Kemp, M. W., Newnham, J. P., ... Wolfs, T. G. A. M. (2016). Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure. Journal of Neuroinflammation, 13, [29]. https://doi.org/10.1186/s12974-016-0492-z
  16. Published
    Willems, M. G. M., Ophelders, D. R. M. G., Nikiforou, M., Jellema, R. K., Butz, A., Delhaas, T., ... Wolfs, T. G. A. M. (2016). Systemic interleukin-2 administration improves lung function and modulates chorioamnionitis-induced pulmonary inflammation in the ovine fetus. American Journal of Physiology-Lung Cellular and Molecular Physiology, 310(1), L1-L7. https://doi.org/10.1152/ajplung.00289.2015
  17. Published
    Nikiforou, M., Willburger, C., de Jong, A. E., Kloosterboer, N., Jellema, R. K., Ophelders, D. R. M. G., ... Wolfs, T. G. A. M. (2016). Global Hypoxia-Ischemia Induced Inflammation and Structural Changes in the Preterm Ovine Gut Which Were Not Ameliorated by Mesenchymal Stem Cell Treatment. Molecular Medicine, 22, 244-257. https://doi.org/10.2119/molmed.2015.00252
  18. 2015
  19. Published
    Jellema, R. K., Ophelders, D. R. M. G., Zwanenburg, A., Nikiforou, M., Delhaas, T., Andriessen, P., ... Kramer, B. W. (2015). Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain. Journal of Neuroinflammation, 12, 241. https://doi.org/10.1186/s12974-015-0459-5
  20. Published
    Hütten, M. C., Goos, T. G., Ophelders, D., Nikiforou, M., Kuypers, E., Willems, M., ... Kramer, B. W. (2015). Fully automated predictive intelligent control of oxygenation (PRICO) in resuscitation and ventilation of preterm lambs. Pediatric Research, 78(6), 657-63. https://doi.org/10.1038/pr.2015.158
  21. Published
    Hütten, M. C., Kuypers, E., Ophelders, D. R., Nikiforou, M., Jellema, R. K., Niemarkt, H. J., ... Kramer, B. W. (2015). Nebulization of Poractant alfa via a vibrating membrane nebulizer in spontaneously breathing preterm lambs with binasal continuous positive pressure ventilation. Pediatric Research, 78(6), 664-9. https://doi.org/10.1038/pr.2015.165
  22. Published
    Nikiforou, M., Vanderlocht, J., Chougnet, C. A., Jellema, R. K., Ophelders, D. R. M. G., Joosten, M., ... Wolfs, T. G. A. M. (2015). Prophylactic Interleukin-2 Treatment Prevents Fetal Gut Inflammation and Injury in an Ovine Model of Chorioamnionitis. Inflammatory Bowel Diseases, 21(9), 2026-2038. https://doi.org/10.1097/MIB.0000000000000455
  23. 2014
  24. Published
    Niemarkt, H. J., Kuypers, E., Jellema, R., Ophelders, D., Huetten, M., Nikiforou, M., ... Kramer, B. W. (2014). Effects of less-invasive surfactant administration on oxygenation, pulmonary surfactant distribution, and lung compliance in spontaneously breathing preterm lambs. Pediatric Research, 76(2), 166-170. https://doi.org/10.1038/pr.2014.66
  25. Published
    Schoberer, M., Arens, J., Erben, A., Ophelders, D., Jellema, R. K., Kramer, B. W., ... Orlikowsky, T. (2014). Miniaturization: The Clue to Clinical Application of the Artificial Placenta. Artificial Organs, 38(3), 208-214. https://doi.org/10.1111/aor.12146
  26. 2013
  27. Published
    Kuypers, E., Jellema, R. K., Ophelders, D. R. M. G., Dudink, J., Nikiforou, M., Wolfs, T. G. A. M., ... Kramer, B. W. (2013). Effects of Intra-Amniotic Lipopolysaccharide and Maternal Betamethasone on Brain Inflammation in Fetal Sheep. PLOS ONE, 8(12), [e81644]. https://doi.org/10.1371/journal.pone.0081644
  28. Published
    Jellema, R. K., Passos, V. L., Ophelders, D. R. M. G., Wolfs, T. G. A. M., Zwanenburg, A., De Munter, S., ... Kramer, B. W. (2013). Systemic G-CSF attenuates cerebral inflammation and hypomyelination but does not reduce seizure burden in preterm sheep exposed to global hypoxia-ischemia. Experimental Neurology, 250, 293-303. https://doi.org/10.1016/j.expneurol.2013.09.026
  29. Published
    Jellema, R. K., Wolfs, T. G. A. M., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., Kuypers, E., ... Kramer, B. W. (2013). Mesenchymal Stem Cells Induce T-Cell Tolerance and Protect the Preterm Brain after Global Hypoxia-Ischemia. PLOS ONE, 8(8), [e73031]. https://doi.org/10.1371/journal.pone.0073031
  30. Published
    Zwanenburg, A., Jellema, R. K., Jennekens, W., Ophelders, D., Vullings, R., van Hunnik, A., ... Andriessen, P. (2013). Heart rate-mediated blood pressure control in preterm fetal sheep under normal and hypoxic-ischemic conditions. Pediatric Research, 73(4), 420-426. https://doi.org/10.1038/pr.2013.15
  31. Published
    Jellema, R. K., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., De Munter, S., Vanderlocht, J., ... Kramer, B. W. (2013). Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep. Journal of Neuroinflammation, 10, [13]. https://doi.org/10.1186/1742-2094-10-13
  32. 2012
  33. Published
    Kuypers, E., Ophelders, D., Jellema, R. K., Kunzmann, S., Gavilanes, A. W., & Kramer, B. W. (2012). White matter injury following fetal inflammatory response syndrome induced by chorioamnionitis and fetal sepsis: Lessons from experimental ovine models. Early Human Development, 88(12), 931-936. https://doi.org/10.1016/j.earlhumdev.2012.09.011
  34. Published
    Seehase, M., Collins, J. J. P., Kuypers, E., Jellema, R. K., Ophelders, D. R. M. G., Ospina, O. L., ... Kramer, B. W. (2012). New Surfactant with SP-B and C Analogs Gives Survival Benefit after Inactivation in Preterm Lambs. PLOS ONE, 7(10), e47631. https://doi.org/10.1371/journal.pone.0047631

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