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- 2019
- PublishedHuetten, M. C., Fehrholz, M., Konrad, F. M., Ophelders, D., Kleintjes, C., Ottensmeier, B., ... Kunzmann, S. (2019). Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 32(6), 1-9. https://doi.org/10.1089/jamp.2019.1528
- PublishedDelhaas, T., Andriessen, P., van Laar, J. O. E. H., Vullings, R., Hermans, B. J. M., Niemarkt, H. J., ... Zwanenburg, A. (2019). Why-aVF can be used in STAN as a proxy for scalp electrode-derived signal; reply to comments by Kjellmer et al. PLOS ONE, 14(8), [0221220]. https://doi.org/10.1371/journal.pone.0221220
- Published
- PublishedGussenhoven, R., Klein, L., Ophelders, D. R. M. G., Habets, D. H. J., Giebel, B., Kramer, B. W., ... Wolfs, T. G. A. M. (2019). Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy. Journal of Clinical Medicine, 8(2), [137]. https://doi.org/10.3390/jcm8020137
- 2018
- PublishedWahl, H. B., Hutten, M. C., Monz, D., Tutdibi, E., Ophelders, D., Nikiforou, M., ... Kramer, B. W. (2018). Vitamin A Supplementation by Endotracheal Application of a Nano-encapsulated Preparation Is Feasible in Ventilated Preterm Lambs. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 31(6), 323-330. [323-330]. https://doi.org/10.1089/jamp.2017.1438
- PublishedGussenhoven, R., Westerlaken, R. J. J., Ophelders, D. R. M. G., Jobe, A. H., Kemp, M. W., Kallapur, S. G., ... Wolfs, T. G. A. M. (2018). Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus. Journal of Neuroinflammation, 15, [113]. https://doi.org/10.1186/s12974-018-1149-x
- PublishedAndriessen, P., Zwanenburg, A., van Laar, J. O. E. H., Vullings, R., Hermans, B. J. M., Niemarkt, H. J., ... Delhaas, T. (2018). ST waveform analysis for monitoring hypoxic distress in fetal sheep after prolonged umbilical cord occlusion. PLOS ONE, 13(4), [e0195978]. https://doi.org/10.1371/journal.pone.0195978
- 2017
- PublishedRicci, F., Salomone, F., Kuypers, E., Ophelders, D., Nikiforou, M., Willems, M., ... Bianco, F. (2017). In Vivo Evaluation of the Acute Pulmonary Response to Poractant Alfa and Bovactant Treatments in Lung-Lavaged Adult Rabbits and in Preterm Lambs with Respiratory Distress Syndrome. Frontiers in pediatrics, 5, [186]. https://doi.org/10.3389/fped.2017.00186
- PublishedOphelders, D. R. M. G. (2017). Novel treatment strategies for the protection of the preterm brain: re-balancing inflammation and regeneration. Maastricht: Datawyse / Universitaire Pers Maastricht. https://doi.org/10.26481/dis.20170317do
- PublishedGussenhoven, R., Ophelders, D. R. M. G., Kemp, M. W., Payne, M. S., Spiller, O. B., Beeton, M. L., ... Wolfs, T. G. A. M. (2017). The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development. Developmental Neuroscience, 39(6), 472-486. https://doi.org/10.1159/000479021
- 2016
- PublishedZwanenburg, A., Hermans, B. J. M., Andriessen, P., Niemarkt, H. J., Jellema, R. K., Ophelders, D. R. M. G., ... Delhaas, T. (2016). Comparison of ECG-based physiological markers for hypoxia in a preterm ovine model. Pediatric Research, 79(6), 907-915. https://doi.org/10.1038/pr.2016.21
- PublishedOphelders, D. R. M. G., Wolfs, T. G. A. M., Jellema, R. K., Zwanenburg, A., Andriessen, P., Delhaas, T., ... Kramer, B. W. (2016). Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia. Stem Cells Translational Medicine, 5(6), 754-763. https://doi.org/10.5966/sctm.2015-0197
- Published
- PublishedOphelders, D. R. M. G., Gussenhoven, R., Lammens, M., Kusters, B., Kemp, M. W., Newnham, J. P., ... Wolfs, T. G. A. M. (2016). Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure. Journal of Neuroinflammation, 13, [29]. https://doi.org/10.1186/s12974-016-0492-z
- PublishedWillems, M. G. M., Ophelders, D. R. M. G., Nikiforou, M., Jellema, R. K., Butz, A., Delhaas, T., ... Wolfs, T. G. A. M. (2016). Systemic interleukin-2 administration improves lung function and modulates chorioamnionitis-induced pulmonary inflammation in the ovine fetus. American Journal of Physiology-Lung Cellular and Molecular Physiology, 310(1), L1-L7. https://doi.org/10.1152/ajplung.00289.2015
- PublishedNikiforou, M., Willburger, C., de Jong, A. E., Kloosterboer, N., Jellema, R. K., Ophelders, D. R. M. G., ... Wolfs, T. G. A. M. (2016). Global Hypoxia-Ischemia Induced Inflammation and Structural Changes in the Preterm Ovine Gut Which Were Not Ameliorated by Mesenchymal Stem Cell Treatment. Molecular Medicine, 22, 244-257. https://doi.org/10.2119/molmed.2015.00252
- 2015
- PublishedJellema, R. K., Ophelders, D. R. M. G., Zwanenburg, A., Nikiforou, M., Delhaas, T., Andriessen, P., ... Kramer, B. W. (2015). Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain. Journal of Neuroinflammation, 12, 241. https://doi.org/10.1186/s12974-015-0459-5
- PublishedHütten, M. C., Goos, T. G., Ophelders, D., Nikiforou, M., Kuypers, E., Willems, M., ... Kramer, B. W. (2015). Fully automated predictive intelligent control of oxygenation (PRICO) in resuscitation and ventilation of preterm lambs. Pediatric Research, 78(6), 657-63. https://doi.org/10.1038/pr.2015.158
- PublishedHütten, M. C., Kuypers, E., Ophelders, D. R., Nikiforou, M., Jellema, R. K., Niemarkt, H. J., ... Kramer, B. W. (2015). Nebulization of Poractant alfa via a vibrating membrane nebulizer in spontaneously breathing preterm lambs with binasal continuous positive pressure ventilation. Pediatric Research, 78(6), 664-9. https://doi.org/10.1038/pr.2015.165
- PublishedNikiforou, M., Vanderlocht, J., Chougnet, C. A., Jellema, R. K., Ophelders, D. R. M. G., Joosten, M., ... Wolfs, T. G. A. M. (2015). Prophylactic Interleukin-2 Treatment Prevents Fetal Gut Inflammation and Injury in an Ovine Model of Chorioamnionitis. Inflammatory Bowel Diseases, 21(9), 2026-2038. https://doi.org/10.1097/MIB.0000000000000455
- 2014
- PublishedNiemarkt, H. J., Kuypers, E., Jellema, R., Ophelders, D., Huetten, M., Nikiforou, M., ... Kramer, B. W. (2014). Effects of less-invasive surfactant administration on oxygenation, pulmonary surfactant distribution, and lung compliance in spontaneously breathing preterm lambs. Pediatric Research, 76(2), 166-170. https://doi.org/10.1038/pr.2014.66
- PublishedSchoberer, M., Arens, J., Erben, A., Ophelders, D., Jellema, R. K., Kramer, B. W., ... Orlikowsky, T. (2014). Miniaturization: The Clue to Clinical Application of the Artificial Placenta. Artificial Organs, 38(3), 208-214. https://doi.org/10.1111/aor.12146
- 2013
- PublishedKuypers, E., Jellema, R. K., Ophelders, D. R. M. G., Dudink, J., Nikiforou, M., Wolfs, T. G. A. M., ... Kramer, B. W. (2013). Effects of Intra-Amniotic Lipopolysaccharide and Maternal Betamethasone on Brain Inflammation in Fetal Sheep. PLOS ONE, 8(12), [e81644]. https://doi.org/10.1371/journal.pone.0081644
- PublishedJellema, R. K., Passos, V. L., Ophelders, D. R. M. G., Wolfs, T. G. A. M., Zwanenburg, A., De Munter, S., ... Kramer, B. W. (2013). Systemic G-CSF attenuates cerebral inflammation and hypomyelination but does not reduce seizure burden in preterm sheep exposed to global hypoxia-ischemia. Experimental Neurology, 250, 293-303. https://doi.org/10.1016/j.expneurol.2013.09.026
- PublishedJellema, R. K., Wolfs, T. G. A. M., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., Kuypers, E., ... Kramer, B. W. (2013). Mesenchymal Stem Cells Induce T-Cell Tolerance and Protect the Preterm Brain after Global Hypoxia-Ischemia. PLOS ONE, 8(8), [e73031]. https://doi.org/10.1371/journal.pone.0073031
- PublishedZwanenburg, A., Jellema, R. K., Jennekens, W., Ophelders, D., Vullings, R., van Hunnik, A., ... Andriessen, P. (2013). Heart rate-mediated blood pressure control in preterm fetal sheep under normal and hypoxic-ischemic conditions. Pediatric Research, 73(4), 420-426. https://doi.org/10.1038/pr.2013.15
- PublishedJellema, R. K., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., De Munter, S., Vanderlocht, J., ... Kramer, B. W. (2013). Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep. Journal of Neuroinflammation, 10, [13]. https://doi.org/10.1186/1742-2094-10-13
- 2012
- PublishedKuypers, E., Ophelders, D., Jellema, R. K., Kunzmann, S., Gavilanes, A. W., & Kramer, B. W. (2012). White matter injury following fetal inflammatory response syndrome induced by chorioamnionitis and fetal sepsis: Lessons from experimental ovine models. Early Human Development, 88(12), 931-936. https://doi.org/10.1016/j.earlhumdev.2012.09.011
- PublishedSeehase, M., Collins, J. J. P., Kuypers, E., Jellema, R. K., Ophelders, D. R. M. G., Ospina, O. L., ... Kramer, B. W. (2012). New Surfactant with SP-B and C Analogs Gives Survival Benefit after Inactivation in Preterm Lambs. PLOS ONE, 7(10), e47631. https://doi.org/10.1371/journal.pone.0047631