To UM home page

Researcher

Kramer, B.W.W.

Full professor - Personal chair, H/MS

View graph of relations
1 - 166 out of 166Page size: 250
  1. 2007
  2. Published
    Kramer, B. W. W. (2007). The multiple effects of exposure to antenatal inflammation on the fetal lung. Maastricht: Datawyse / Universitaire Pers Maastricht.
  3. 2010
  4. Published
    Kramer, B. W., Kallapur, S. G., Moss, T. J. M., Nitsos, I., Polglase, G. P., Newnham, J. P., & Jobe, A. H. (2010). Modulation of fetal inflammatory response on exposure to lipopolysaccharide by chorioamnion, lung, or gut in sheep. American Journal of Obstetrics and Gynecology, 202(1), 77.e1-77.e9. https://doi.org/10.1016/j.ajog.2009.07.058
  5. Published
    Gavilanes, A. W. D., Gantert, M., Strackx, E., Zimmermann, L. J., Seeldrayers, S., Vles, J. S. H., & Kramer, B. W. (2010). Increased EEG delta frequency corresponds to chorioamnionitis-related brain injury. Frontiers in bioscience - scholar edition, 2, 432-8.
  6. Published
    Smit, A. L., Stokroos, R. J., Litjens, S. G. H., Kremer, B., & Kramer, B. W. (2010). Potential role for lipopolysaccharide in congenital sensorineural hearing loss. Journal of Medical Microbiology, 59(4), 377-383. https://doi.org/10.1099/jmm.0.015792-0
  7. Published
    Kunzmann, S., Glogger, K., Been, J. V., Kallapur, S. G., Nitsos, I., Moss, T. J. M., ... Kramer, B. W. (2010). Thymic changes after chorioamnionitis induced by intraamniotic lipopolysaccharide in fetal sheep. American Journal of Obstetrics and Gynecology, 202(5), 476.e1-476.e9. https://doi.org/10.1016/j.ajog.2010.02.035
  8. Published
    Gantert, M., Been, J. V., Gavilanes, A. W. D., Garnier, Y., Zimmermann, L. J. I., & Kramer, B. W. (2010). Chorioamnionitis: a multiorgan disease of the fetus? Journal of Perinatology, 30, S21-S30. https://doi.org/10.1038/jp.2010.96
  9. Published
    Ladenburger, A., Seehase, M., Kramer, B. W., Thomas, W., Wirbelauer, J., Speer, C. P., & Kunzmann, S. (2010). Glucocorticoids potentiate IL-6-induced SP-B expression in H441 cells by enhancing the JAK-STAT signaling pathway. American Journal of Physiology-Lung Cellular and Molecular Physiology, 299(4), L578-L584. https://doi.org/10.1152/ajplung.00055.2010
  10. Published
    Collins, J. J. P., Kallapur, S. G., Knox, C. L., Nitsos, I., Polglase, G. R., Pillow, J. J., ... Kramer, B. W. (2010). Inflammation in fetal sheep from intra-amniotic injection of Ureaplasma parvum. American Journal of Physiology-Lung Cellular and Molecular Physiology, 299(6), L852-L860. https://doi.org/10.1152/ajplung.00183.2010
  11. 2011
  12. Published
    Kramer, B. W. (2011). Chorioamnionitis - New Ideas from Experimental Models. Neonatology, 99(4), 320-325. https://doi.org/10.1159/000326620
  13. Published
    Been, J. V., Degraeuwe, P. L., Kramer, B. W., & Zimmermann, L. J. I. (2011). Antenatal steroids and neonatal outcome after chorioamnionitis: a meta-analysis. Bjog-an International Journal of Obstetrics and Gynaecology, 118(2), 113-122. https://doi.org/10.1111/j.1471-0528.2010.02751.x
  14. Published
    Cox, T., Kallapur, S. G., Keelan, J. A., Saito, M., Jobe, A. H., Kramer, B., ... Kemp, M. W. (2011). Precocious Maturation of the Fetal Ovine Skin Following In Utero Exposure to LPS. Reproductive Sciences, 18(3), 237A-237A.
  15. Published
    Wolfs, T. G. A. M., Kallapur, S. G., Polglase, G. R., Pillow, J. J., Nitsos, I., Newnham, J. P., ... Kramer, B. W. (2011). IL-1 alpha Mediated Chorioamnionitis Induces Depletion of FoxP3+Cells and Ileal Inflammation in the Ovine Fetal Gut. PLOS ONE, 6(3), 9. https://doi.org/10.1371/journal.pone.0018355
  16. Published
    Lee, A. J. X., Lambermont, V. A. C., Pillow, J. J., Polglase, G. R., Nitsos, I., Newnham, J. P., ... Kramer, B. W. (2011). Fetal responses to lipopolysaccharide-induced chorioamnionitis alter immune and airway responses in 7-week-old sheep. American Journal of Obstetrics and Gynecology, 204(4), 364. https://doi.org/10.1016/j.ajog.2010.11.015
  17. Published
    Thomas, W., Seidenspinner, S., Kramer, B. W., Wirbelauer, J., Kawczynska-Leda, N., Szymankiewicz, M., & Speer, C. P. (2011). Airway Angiopoietin-2 in Ventilated Very Preterm Infants: Association With Prenatal Factors and Neonatal Outcome. Pediatric Pulmonology, 46(8), 777-784. https://doi.org/10.1002/ppul.21435
  18. Published
    Seehase, M., Gantert, M., Ladenburger, A., Garnier, Y., Kunzmann, S., Thomas, W., ... Kramer, B. W. (2011). Myocardial Response in Preterm Fetal Sheep Exposed to Systemic Endotoxinaemia. Pediatric Research, 70(3), 242-246. https://doi.org/10.1203/PDR.0b013e318225fbcb
  19. Published
    Kallapur, S. G., Kramer, B. W., Nitsos, I., Pillow, J. J., Collins, J. J. P., Polglase, G. R., ... Jobe, A. H. (2011). Pulmonary and systemic inflammatory responses to intra-amniotic IL-1 alpha in fetal sheep. American Journal of Physiology-Lung Cellular and Molecular Physiology, 301(3), L285-L295. https://doi.org/10.1152/ajplung.00446.2010
  20. Published
    Kallapur, S. G., Kramer, B. W., Knox, C. L., Berry, C. A., Collins, J. J. P., Kemp, M. W., ... Jobe, A. H. (2011). Chronic Fetal Exposure to Ureaplasma parvum Suppresses Innate Immune Responses in Sheep. Journal of Immunology, 187(5), 2688-2695. https://doi.org/10.4049/jimmunol.1100779
  21. Published
    Kramer, B. W. W. (2011). May the evidence be with you... Maastricht: Maastricht University. https://doi.org/10.26481/spe.20111006bk
  22. Published
    Kunzmann, S., Collins, J. J. P., Yang, Y., Uhlig, S., Kallapur, S. G., Speer, C. P., ... Kramer, B. W. (2011). Antenatal Inflammation Reduces Expression of Caveolin-1 and Influences Multiple Signaling Pathways in Preterm Fetal Lungs. American Journal of Respiratory Cell and Molecular Biology, 45(5), 969-976. https://doi.org/10.1165/rcmb.2010-0519OC
  23. Published
    Kemp, M. W., Saito, M., Kallapur, S. G., Jobe, A. H., Keelan, J. A., Li, S., ... Newnham, J. P. (2011). Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum. Reproductive Sciences, 18(11), 1128-1137. https://doi.org/10.1177/1933719111408114
  24. Published
    Berry, C. A., Nitsos, I., Hillman, N. H., Pillow, J. J., Polglase, G. R., Kramer, B. W., ... Kallapur, S. G. (2011). Interleukin-1 in Lipopolysaccharide Induced Chorioamnionitis in the Fetal Sheep. Reproductive Sciences, 18(11), 1092-1102. https://doi.org/10.1177/1933719111404609
  25. Published
    Niemarkt, H. J., Jennekens, W., Pasman, J. W., Katgert, T., van Pul, C., Gavtlanes, A. W. D., ... Andriessen, P. (2011). Maturational Changes in Automated EEG Spectral Power Analysis in Preterm Infants. Pediatric Research, 70(5), 529-534. https://doi.org/10.1203/PDR.0b013e31822d748b
  26. Published
    Onland, W., Offringa, M., Cools, F., De Jaegere, A. P., Rademaker, K., Blom, H., ... van Kaam, A. H. (2011). Systemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study); a multicenter randomized placebo controlled trial. Bmc Pediatrics, 11(1), 102. https://doi.org/10.1186/1471-2431-11-102
  27. 2012
  28. Published
    Gantert, M., Jellema, R. K., Heineman, H., Gantert, J., Collins, J. J. P., Seehase, M., ... Kramer, B. W. (2012). Lipopolysaccharide-Induced Chorioamnionitis Is Confined to One Amniotic Compartment in Twin Pregnant Sheep. Neonatology, 102(2), 81-88. https://doi.org/10.1159/000338015
  29. Published
    Willems, C. H. M. P., Kloosterboer, N., Kunzmann, S., Kramer, B. W., Zimmermann, L. J. I., & van Iwaarden, J. F. (2012). Dissociation of transforming growth factors beta 1 and beta 2 from surfactant protein A (SP-A) by deglycosylation or deoxycholate treatment. Journal of Immunological Methods, 375(1-2), 111-117. https://doi.org/10.1016/j.jim.2011.09.014
  30. Published
    Kuypers, E., Collins, J. J. P., Kramer, B. W., Ofman, G., Nitsos, I., Pillow, J. J., ... Kallapur, S. G. (2012). Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs. American Journal of Physiology-Lung Cellular and Molecular Physiology, 302(4), L380-L389. https://doi.org/10.1152/ajplung.00338.2011
  31. Published
    Kaemmerer, E., Schneider, U., Klaus, C., Plum, P., Reinartz, A., Adolf, M., ... Gassler, N. (2012). Increased levels of deleted in malignant brain tumours 1 (DMBT1) in active bacteria-related appendicitis. Histopathology, 60(4), 561-569. https://doi.org/10.1111/j.1365-2559.2011.04159.x
  32. Published
    Strackx, E., Gantert, M., Moers, V., van Kooten, I. A. J., Rieke, R., Hurter, H., ... Kramer, B. W. (2012). Increased Number of Cerebellar Granule Cells and Astrocytes in the Internal Granule Layer in Sheep Following Prenatal Intra-amniotic Injection of Lipopolysaccharide. Cerebellum, 11(1), 132-144. https://doi.org/10.1007/s12311-011-0297-7
  33. Published
    Willems, C. H. M. P., Urlichs, F., Seidenspinner, S., Kunzmann, S., Speer, C. P., & Kramer, B. W. (2012). Poractant alfa (Curosurf (R)) increases phagocytosis of apoptotic neutrophils by alveolar macrophages in vivo. Respiratory Research, 13, 17. https://doi.org/10.1186/1465-9921-13-17
  34. Published
    Wolfs, T. G. A. M., Jellema, R. K., Turrisi, G., Becucci, E., Buonocore, G., & Kramer, B. W. (2012). Inflammation-induced immune suppression of the fetus: a potential link between chorioamnionitis and postnatal early onset sepsis. Journal of Maternal-Fetal & Neonatal Medicine, 25, 8-11. https://doi.org/10.3109/14767058.2012.664447
  35. Published
    Niemarkt, H. J., Jennekens, W., Maartens, I. A., Wassenberg, T., van Aken, M., Katgert, T., ... Andriessen, P. (2012). Multi-channel amplitude-integrated EEG characteristics in preterm infants with a normal neurodevelopment at two years of corrected age. Early Human Development, 88(4), 209-216. https://doi.org/10.1016/j.earlhumdev.2011.08.008
  36. Published
    Kuypers, E., Collins, J. J. P., Jellema, R. K., Wolfs, T. G. A. M., Kemp, M. W., Nitsos, I., ... Kramer, B. W. (2012). Ovine Fetal Thymus Response to Lipopolysaccharide-Induced Chorioamnionitis and Antenatal Corticosteroids. PLOS ONE, 7(5), [e38257]. https://doi.org/10.1371/journal.pone.0038257
  37. Published
    Andre, M. C., Gille, C., Glemser, P., Woiterski, J., Hsu, H-Y., Spring, B., ... Orlikowsky, T. W. (2012). Bacterial reprogramming of PBMCs impairs monocyte phagocytosis and modulates adaptive T cell responses. Journal of Leukocyte Biology, 91(6), 977-989. https://doi.org/10.1189/jlb.0911474
  38. Published
    Schoberer, M., Arens, J., Lohr, A., Seehase, M., Jellema, R. K., Collins, J. J., ... Orlikowsky, T. (2012). Fifty Years of Work on the Artificial Placenta: Milestones in the History of Extracorporeal Support of the Premature Newborn. Artificial Organs, 36(6), 512-516. https://doi.org/10.1111/j.1525-1594.2011.01404.x
  39. Published
    Gantert, M., Kreczmanski, P., Kuypers, E., Jellema, R., Strackx, E., Bastian, N., ... Kramer, B. W. (2012). Effects of in utero endotoxemia on the ovine fetal brain: a model for schizophrenia? Frontiers in Bioscience, Elite edition, 1(4), 2845-53.
  40. Published
    Buonocore, G., Perrone, S., Turrisi, G., Kramer, B. W., & Balduini, W. (2012). New Pharmacological Approaches in Infants with Hypoxic-Ischemic Encephalopathy. Current Pharmaceutical Design, 18(21), 3086-3100. https://doi.org/10.2174/1381612811209023086
  41. Published
    Gortner, L., Felderhoff-Mueser, U., Monz, D., Bieback, K., Klueter, H., Jellema, R., ... Giebel, B. (2012). Regenerative Therapies in Neonatology: Clinical Perspectives. Klinische Padiatrie, 224(4), 233-240. https://doi.org/10.1055/s-0032-1316296
  42. Published
    Lambermont, V. A. C., Been, J. V., Kunzmann, S., Vanterpool, S. F., Newnham, J. P., Kallapur, S. G., ... Kramer, B. W. (2012). Sex Differences in Lung Gas Volumes After Lipopolysaccharide-Induced Chorioamnionitis in Fetal Sheep. Gender Medicine, 9(4), 278-286. https://doi.org/10.1016/j.genm.2012.05.005
  43. Published
    Laug, R., Fehrholz, M., Schuetze, N., Kramer, B. W., Krump-Konvalinkova, V., Speer, C. P., & Kunzmann, S. (2012). IFN-gamma and TNF-alpha Synergize to Inhibit CTGF Expression in Human Lung Endothelial Cells. PLOS ONE, 7(9), [e45430]. https://doi.org/10.1371/journal.pone.0045430
  44. Published
    Schlepuetz, M., Rieg, A. D., Seehase, S., Spillner, J., Perez-Bouza, A., Braunschweig, T., ... Martin, C. (2012). Neurally Mediated Airway Constriction in Human and Other Species: A Comparative Study Using Precision-Cut Lung Slices (PCLS). PLOS ONE, 7(10), [e47344]. https://doi.org/10.1371/journal.pone.0047344
  45. Published
    Seehase, M., Collins, J. J. P., Kuypers, E., Jellema, R. K., Ophelders, D. R. M. G., Ospina, O. L., ... Kramer, B. W. (2012). New Surfactant with SP-B and C Analogs Gives Survival Benefit after Inactivation in Preterm Lambs. PLOS ONE, 7(10), e47631. https://doi.org/10.1371/journal.pone.0047631
  46. Published
    Collins, J. J. P., Kuypers, E., Nitsos, I., Pillow, J. J., Polglase, G. R., Kemp, M. W., ... Kramer, B. W. (2012). LPS-induced chorioamnionitis and antenatal corticosteroids modulate Shh signaling in the ovine fetal lung. American Journal of Physiology-Lung Cellular and Molecular Physiology, 303(9), L778-L787. https://doi.org/10.1152/ajplung.00280.2011
  47. Published
    Willems, C. H. M. P., Zimmermann, L. J. I., Langen, R. M. R., van den Bosch, M. J. A., Kloosterboer, N., Kramer, B. W., & van Iwaarden, J. F. (2012). Surfactant Protein A Influences Reepithelialization in an Alveolocapillary Model System. Lung, 190(6), 661-669. https://doi.org/10.1007/s00408-012-9424-6
  48. Published
    Kuypers, E., Ophelders, D., Jellema, R. K., Kunzmann, S., Gavilanes, A. W., & Kramer, B. W. (2012). White matter injury following fetal inflammatory response syndrome induced by chorioamnionitis and fetal sepsis: Lessons from experimental ovine models. Early Human Development, 88(12), 931-936. https://doi.org/10.1016/j.earlhumdev.2012.09.011
  49. Published
    Fehrholz, M., Bersani, I., Kramer, B. W., Speer, C. P., & Kunzmann, S. (2012). Synergistic Effect of Caffeine and Glucocorticoids on Expression of Surfactant Protein B (SP-B) mRNA. PLOS ONE, 7(12), [e51575]. https://doi.org/10.1371/journal.pone.0051575
  50. 2013
  51. Published
    Collins, J. J. P., Kallapur, S. G., Knox, C. L., Kemp, M. W., Kuypers, E., Zimmermann, L. J. I., ... Kramer, B. W. (2013). Repeated Intrauterine Exposures to Inflammatory Stimuli Attenuated Transforming Growth Factor-beta Signaling in the Ovine Fetal Lung. Neonatology, 104(1), 49-55. https://doi.org/10.1159/000350548
  52. Published
    Jellema, R. K., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., De Munter, S., Vanderlocht, J., ... Kramer, B. W. (2013). Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep. Journal of Neuroinflammation, 10, [13]. https://doi.org/10.1186/1742-2094-10-13
  53. Published
    Vlassaks, E., Strackx, E., Vles, J. S. H., Nikiforou, M., Martinez-Martinez, P., Kramer, B. W., & Gavilanes, A. W. D. (2013). Fetal asphyctic preconditioning modulates the acute cytokine response thereby protecting against perinatal asphyxia in neonatal rats. Journal of Neuroinflammation, 10, [14]. https://doi.org/10.1186/1742-2094-10-14
  54. Published
    Been, J. V., Lievense, S., Zimmermann, L. J. I., Kramer, B. W., & Wolfs, T. G. A. M. (2013). Chorioamnionitis as a Risk Factor for Necrotizing Enterocolitis: A Systematic Review and Meta-Analysis. The Journal of Pediatrics, 162(2), 236-242. https://doi.org/10.1016/j.jpeds.2012.07.012
  55. Published
    Engel, M., Nowacki, R. M. E., Reiss, L. K., Uhlig, S., Willems, C. H. M. P., Kloosterboer, N., ... Kramer, B. W. (2013). Comparison of Recruitment Manoeuvres in Ventilated Sheep with Acute Respiratory Distress Syndrome. Lung, 191(1), 77-86. https://doi.org/10.1007/s00408-012-9428-2
  56. Published
    Vlassaks, E., Gavilanes, A. W. D., Vles, J. S. H., Deville, S., Kramer, B. W., Strackx, E., & Martinez-Martinez, P. (2013). The effects of fetal and perinatal asphyxia on neuronal cytokine levels and ceramide metabolism in adulthood. Journal of Neuroimmunology, 255(1-2), 97-101. https://doi.org/10.1016/j.jneuroim.2012.09.011
  57. Published
    Collins, J. J. P., Kunzmann, S., Kuypers, E., Kemp, M. W., Speer, C. P., Newnham, J. P., ... Kramer, B. W. (2013). Antenatal glucocorticoids counteract LPS changes in TGF-beta pathway and caveolin-1 in ovine fetal lung. American Journal of Physiology-Lung Cellular and Molecular Physiology, 304(6), L438-L444. https://doi.org/10.1152/ajplung.00251.2012
  58. Published
    Zwanenburg, A., Jellema, R. K., Jennekens, W., Ophelders, D., Vullings, R., van Hunnik, A., ... Andriessen, P. (2013). Heart rate-mediated blood pressure control in preterm fetal sheep under normal and hypoxic-ischemic conditions. Pediatric Research, 73(4), 420-426. https://doi.org/10.1038/pr.2013.15
  59. Published
    Kallapur, S. G., Kramer, B. W., & Jobe, A. H. (2013). Ureaplasma and BPD. Seminars in Perinatology, 37(2), 94-101. https://doi.org/10.1053/j.semperi.2013.01.005
  60. Published
    Robinson, J. W., Dando, S. J., Nitsos, I., Newnham, J., Polglase, G. R., Kallapur, S. G., ... Knox, C. L. (2013). Ureaplasma parvum Serovar 3 Multiple Banded Antigen Size Variation after Chronic Intra-Amniotic Infection/Colonization. PLOS ONE, 8(4), [e62746]. https://doi.org/10.1371/journal.pone.0062746
  61. Published
    Wolfs, T. G. A. M., Kallapur, S. G., Knox, C. L., Thuijls, G., Nitsos, I., Polglase, G. R., ... Kramer, B. W. (2013). Antenatal ureaplasma infection impairs development of the fetal ovine gut in an IL-1-dependent manner. Mucosal Immunology, 6(3), 547-556. https://doi.org/10.1038/mi.2012.97
  62. Published
    Snyder, C. C., Wolfe, K. B., Gisslen, T., Knox, C. L., Kemp, M. W., Kramer, B. W., ... Kallapur, S. G. (2013). Modulation of lipopolysaccharide-induced chorioamnionitis by Ureaplasma parvum in sheep. American Journal of Obstetrics and Gynecology, 208(5), [399.e1]. https://doi.org/10.1016/j.ajog.2013.02.018
  63. Published
    Kemp, M. W., Kannan, P. S., Saito, M., Newnham, J. P., Cox, T., Jobe, A. H., ... Kallapur, S. G. (2013). Selective Exposure of the Fetal Lung and Skin/Amnion (but Not Gastro-Intestinal Tract) to LPS Elicits Acute Systemic Inflammation in Fetal Sheep. PLOS ONE, 8(5), [e63355]. https://doi.org/10.1371/journal.pone.0063355
  64. Published
    Kunzmann, S., Collins, J. J. P., Kuypers, E., & Kramer, B. W. (2013). Thrown off balance: the effect of antenatal inflammation on the developing lung and immune system. American Journal of Obstetrics and Gynecology, 208(6), 429-437. https://doi.org/10.1016/j.ajog.2013.01.008
  65. Published
    Smit, A. L., Seehase, M., Stokroos, R. J., Jellema, R. K., Felipe, L., Chenault, M. N., ... Kramer, B. W. (2013). Functional impairment of the auditory pathway after perinatal asphyxia and the short-term effect of perinatal propofol anesthesia in lambs. Pediatric Research, 74(1), 34-38. https://doi.org/10.1038/pr.2013.64
  66. Published
    Kuypers, E., Wolfs, T. G. A. M., Collins, J. J. P., Jellema, R. K., Newnham, J. P., Kemp, M. W., ... Kramer, B. W. (2013). Intraamniotic Lipopolysaccharide Exposure Changes Cell Populations and Structure of the Ovine Fetal Thymus. Reproductive Sciences, 20(8), 946-956. https://doi.org/10.1177/1933719112472742
  67. Published
    Jellema, R. K., Wolfs, T. G. A. M., Passos, V. L., Zwanenburg, A., Ophelders, D. R. M. G., Kuypers, E., ... Kramer, B. W. (2013). Mesenchymal Stem Cells Induce T-Cell Tolerance and Protect the Preterm Brain after Global Hypoxia-Ischemia. PLOS ONE, 8(8), [e73031]. https://doi.org/10.1371/journal.pone.0073031
  68. Published
    Wolfe, K. B., Snyder, C. C., Gisslen, T., Kemp, M. W., Newnham, J. P., Kramer, B. W., ... Kallapur, S. (2013). Modulation of Lipopolysaccharide-Induced Chorioamnionitis in Fetal Sheep by Maternal Betamethasone. Reproductive Sciences, 20(12), 1447-1454. https://doi.org/10.1177/1933719113488445
  69. Published
    Jellema, R. K., Passos, V. L., Ophelders, D. R. M. G., Wolfs, T. G. A. M., Zwanenburg, A., De Munter, S., ... Kramer, B. W. (2013). Systemic G-CSF attenuates cerebral inflammation and hypomyelination but does not reduce seizure burden in preterm sheep exposed to global hypoxia-ischemia. Experimental Neurology, 250, 293-303. https://doi.org/10.1016/j.expneurol.2013.09.026
  70. Published
    Kuypers, E., Jellema, R. K., Ophelders, D. R. M. G., Dudink, J., Nikiforou, M., Wolfs, T. G. A. M., ... Kramer, B. W. (2013). Effects of Intra-Amniotic Lipopolysaccharide and Maternal Betamethasone on Brain Inflammation in Fetal Sheep. PLOS ONE, 8(12), [e81644]. https://doi.org/10.1371/journal.pone.0081644
  71. 2014
  72. Published
    Fehrholz, M., Huetten, M., Kramer, B. W., Speer, C. P., & Kunzmann, S. (2014). Amplification of steroid-mediated SP-B expression by physiological levels of caffeine. American Journal of Physiology-Lung Cellular and Molecular Physiology, 306(1), L101-L109. https://doi.org/10.1152/ajplung.00257.2013
  73. Published
    Kuypers, E., Willems, M. G. M., Collins, J. J. P., Wolfs, T. G. A. M., Nitsos, I., Pillow, J. J., ... Kramer, B. W. (2014). Altered canonical Wingless-It signaling in the ovine fetal lung after exposure to intra-amniotic lipopolysaccharide and antenatal betamethasone. Pediatric Research, 75(2), 281-287. https://doi.org/10.1038/pr.2013.226
  74. Published
    Gisslen, T., Hillman, N. H., Musk, G. C., Kemp, M. W., Kramer, B. W., Senthamaraikannan, P., ... Kallapur, S. G. (2014). Repeated exposure to intra-amniotic LPS partially protects against adverse effects of intravenous LPS in preterm lambs. Innate Immunity, 20(2), 214-224. https://doi.org/10.1177/1753425913488430
  75. Published
    Willems, C. H. M. P., Zimmermann, L. J. I., Kloosterboer, N., Kramer, B. W., & van Iwaarden, J. F. (2014). Surfactant protein A binds TGF-beta 1 with high affinity and stimulates the TGF-beta pathway. Innate Immunity, 20(2), 192-199. https://doi.org/10.1177/1753425913488012
  76. Published
    Wolfs, T. G. A. M., Kramer, B. W., Thuijls, G., Kemp, M. W., Saito, M., Willems, M. G. M., ... Kallapur, S. G. (2014). Chorioamnionitis-induced fetal gut injury is mediated by direct gut exposure of inflammatory mediators or by lung inflammation. American Journal of Physiology-Gastrointestinal and Liver Physiology, 306(5), G382-G393. https://doi.org/10.1152/ajpgi.00260.2013
  77. Published
    Schoberer, M., Arens, J., Erben, A., Ophelders, D., Jellema, R. K., Kramer, B. W., ... Orlikowsky, T. (2014). Miniaturization: The Clue to Clinical Application of the Artificial Placenta. Artificial Organs, 38(3), 208-214. https://doi.org/10.1111/aor.12146
  78. Published
    Lambermont, V. A., Kuypers, E., Collins, J. J. R., Pillow, J. J., Newnham, J. P., Polglase, G. R., ... Kramer, B. W. (2014). Effects of intra-amniotic lipopolysaccharide exposure on the fetal lamb lung as gestation advances. Pediatric Research, 75(4), 500-506. https://doi.org/10.1038/pr.2014.3
  79. Published
    Saito, M., Payne, M. S., Miura, Y., Ireland, D. J., Stock, S., Kallapur, S. G., ... Kemp, M. W. (2014). Polymyxin B Agonist Capture Therapy for Intrauterine Inflammation: Proof-of-Principle in a Fetal Ovine Model. Reproductive Sciences, 21(5), 623-631. https://doi.org/10.1177/1933719113508820
  80. Published
    Payne, M. S., Kemp, M. W., Kallapur, S. G., Kannan, P. S., Saito, M., Miura, Y., ... Jobe, A. H. (2014). Intrauterine Candida albicans infection elicits severe inflammation in fetal sheep. Pediatric Research, 75(6), 716-722. https://doi.org/10.1038/pr.2014.35
  81. Published
    Niemarkt, H. J., Kuypers, E., Jellema, R., Ophelders, D., Huetten, M., Nikiforou, M., ... Kramer, B. W. (2014). Effects of less-invasive surfactant administration on oxygenation, pulmonary surfactant distribution, and lung compliance in spontaneously breathing preterm lambs. Pediatric Research, 76(2), 166-170. https://doi.org/10.1038/pr.2014.66
  82. Published
    Reisinger, K. W., Elst, M., Derikx, J. P. M., Nikkels, P. G. J., de Vries, B., Adriaanse, M. P. M., ... Wolfs, T. G. A. M. (2014). Intestinal fatty acid-binding protein: a possible marker for gut maturation. Pediatric Research, 76(3), 261-268. https://doi.org/10.1038/pr.2014.89
  83. Published
    Lambermont, V. A., Schleputz, M., Dassow, C., Konig, P., Zimmermann, L. J., Uhlig, S., ... Martin, C. (2014). Comparison of airway responses in sheep of different age in precision-cut lung slices (PCLS). PLOS ONE, 9(9), [e97610]. https://doi.org/10.1371/journal.pone.0097610
  84. Published
    van Ganzewinkel, C., Anand, K. J. S., Kramer, B. W., & Andriessen, P. (2014). Chronic Pain in the Newborn Toward a Definition. Clinical Journal of Pain, 30(11), 970-977. https://doi.org/10.1097/AJP.0000000000000056
  85. Published
    Schmidt, A. F., Kannan, P. S., Kemp, M. W., Kramer, B. W., Newnham, J. P., Jobe, A. H., & Kallapur, S. G. (2014). Intra-amniotic LPS modulates expression of antimicrobial peptides in the fetal sheep lung. Pediatric Research, 76(5), 441-447. https://doi.org/10.1038/pr.2014.113
  86. Published
    Reisinger, K. W., de Vaan, L., Kramer, B. W., Wolfs, T. G. A. M., van Heurn, E., & Derikx, J. P. M. (2014). Breast-Feeding Improves Gut Maturation Compared With Formula Feeding in Preterm Babies. Journal of Pediatric Gastroenterology and Nutrition, 59(6), 720-724. https://doi.org/10.1097/MPG.0000000000000523
  87. 2015
  88. Published
    Lener, T., Gimona, M., Aigner, L., Boerger, V., Buzas, E., Camussi, G., ... Giebel, B. (2015). Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. Journal of Extracellular Vesicles , 4, [30087]. https://doi.org/10.3402/jev.v4.30087
  89. Published
    Strackx, E., Jellema, R. K., Rieke, R., Gussenhoven, R., Vles, J. S. H., Kramer, B. W., & Gavilanes, A. W. D. (2015). Intra-Amniotic LPS Induced Region-Specific Changes in Presynaptic Bouton Densities in the Ovine Fetal Brain. BioMed Research International, [276029]. https://doi.org/10.1155/2015/276029
  90. Published
    Strackx, E., Sparnaaij, M. A. R., Vlassaks, E., Jellema, R., Kuypers, E., Vles, J. S. H., ... Gavilanes, A. W. D. (2015). Lipopolysaccharide-Induced Chorioamnionitis Causes Acute Inflammatory Changes in the Ovine Central Nervous System. Cns & Neurological Disorders-Drug Targets, 14(1), 77-84. https://doi.org/10.2174/1871527314666150116120029
  91. Published
    Chedraui, P., Andrade, M. E., Salazar-Pousada, D., Escobar, G. S., Hidalgo, L., Ramirez, C., ... Gavilanes, A. W. D. (2015). Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in the placenta of pregnancies complicated with preeclampsia. Gynecological Endocrinology, 31(7), 569-572. https://doi.org/10.3109/09513590.2015.1031104
  92. Published
    Nikiforou, M., Vlassaks, E., Strackx, E., Kramer, B. W., Vles, J. S. H., & Gavilanes, A. W. D. (2015). Preconditioning by Oxygen-Glucose Deprivation Preserves Cell Proliferation and Reduces Cytotoxicity in Primary Astrocyte Cultures. Cns & Neurological Disorders-Drug Targets, 14(1), 61-67. https://doi.org/10.2174/1871527314666150116120518
  93. Published
    Kuypers, E., Willems, M. G. M., Jellema, R. K., Kemp, M. W., Newnham, J. P., Delhaas, T., ... Kramer, B. W. (2015). Responses of the spleen to intraamniotic lipopolysaccharide exposure in fetal sheep. Pediatric Research, 77(1), 29-35. https://doi.org/10.1038/pr.2014.152
  94. Published
    Niemarkt, H. J., de Meij, T. G. J., van de Velde, M. E., van der Schee, M. P., van Goudoever, J. B., Kramer, B. W., ... de Boer, N. K. H. (2015). Necrotizing Enterocolitis: A Clinical Review on Diagnostic Biomarkers and the Role of the Intestinal Microbiota. Inflammatory Bowel Diseases, 21(2), 436-444. https://doi.org/10.1097/MIB.0000000000000184
  95. Published
    Zwanenburg, A., Andriessen, P., Jellema, R. K., Niemarkt, H. J., Wolfs, T. G. A. M., Kramer, B. W., & Delhaas, T. (2015). Using trend templates in a neonatal seizure algorithm improves detection of short seizures in a foetal ovine model. Physiological Measurement, 36(3), 369-384. https://doi.org/10.1088/0967-3334/36/3/369
  96. Published
    Maneenil, G., Kemp, M. W., Kannan, P. S., Kramer, B. W., Saito, M., Newnham, J. P., ... Kallapur, S. G. (2015). Oral, Nasal and Pharyngeal Exposure to Lipopolysaccharide Causes a Fetal Inflammatory Response in Sheep. PLOS ONE, 10(3), [e0119281]. https://doi.org/10.1371/journal.pone.0119281
  97. Published
    Cetinkaya, M., Cansev, M., Cekmez, F., Tayman, C., Canpolat, F. E., Kafa, I. M., ... Sarici, S. U. (2015). Protective Effects of Valproic Acid, a Histone Deacetylase Inhibitor, against Hyperoxic Lung Injury in a Neonatal Rat Model. PLOS ONE, 10(5), [e0126028]. https://doi.org/10.1371/journal.pone.0126028
  98. Published
    Maneenil, G., Payne, M. S., Kannan, P. S., Kallapur, S. G., Kramer, B. W., Newnham, J. P., ... Kemp, M. W. (2015). Fluconazole treatment of intrauterine Candida albicans infection in fetal sheep. Pediatric Research, 77(6), 740-748. https://doi.org/10.1038/pr.2015.48
  99. Published
    Kroener, C., Reu, S., Teusch, V., Schams, A., Grimmelt, A-C., Barker, M., ... Griese, M. (2015). Genotype alone does not predict the clinical course of SFTPC deficiency in paediatric patients. European Respiratory Journal, 46(1), 197-206. https://doi.org/10.1183/09031936.00129414
  100. Published
    Halbertsma, F. J. J., Mohns, T., Bok, L. A., Niemarkt, H. J., & Kramer, B. W. (2015). Prevalence of systemic air-embolism after prolonged cardiopulmonary resuscitation in newborns: A pilot study. Resuscitation, 93, 96-101. https://doi.org/10.1016/j.resuscitation.2015.06.007
  101. Published
    de Meij, T. G. J., van der Schee, M. P. C., Berkhout, D. J. C., van de Velde, M. E., Jansen, A. E., Kramer, B. W., ... de Boer, N. K. H. (2015). Early Detection of Necrotizing Enterocolitis by Fecal Volatile Organic Compounds Analysis. Journal of Pediatrics, 167(3), 562-+. https://doi.org/10.1016/j.jpeds.2015.05.044
  102. Published
    Nikiforou, M., Vanderlocht, J., Chougnet, C. A., Jellema, R. K., Ophelders, D. R. M. G., Joosten, M., ... Wolfs, T. G. A. M. (2015). Prophylactic Interleukin-2 Treatment Prevents Fetal Gut Inflammation and Injury in an Ovine Model of Chorioamnionitis. Inflammatory Bowel Diseases, 21(9), 2026-2038. https://doi.org/10.1097/MIB.0000000000000455
  103. Published
    Mazzucchelli, I., Lisini, D., Garofoli, F., Dragoni, S., Angelini, M., Pozzi, M., ... Stronati, M. (2015). Expression and function of toll-like receptors in human circulating endothelial colony forming cells. Immunology Letters, 168(1), 98-104. https://doi.org/10.1016/j.imlet.2015.09.014
  104. Published
    Hütten, M. C., Goos, T. G., Ophelders, D., Nikiforou, M., Kuypers, E., Willems, M., ... Kramer, B. W. (2015). Fully automated predictive intelligent control of oxygenation (PRICO) in resuscitation and ventilation of preterm lambs. Pediatric Research, 78(6), 657-63. https://doi.org/10.1038/pr.2015.158
  105. Published
    Hütten, M. C., Kuypers, E., Ophelders, D. R., Nikiforou, M., Jellema, R. K., Niemarkt, H. J., ... Kramer, B. W. (2015). Nebulization of Poractant alfa via a vibrating membrane nebulizer in spontaneously breathing preterm lambs with binasal continuous positive pressure ventilation. Pediatric Research, 78(6), 664-9. https://doi.org/10.1038/pr.2015.165
  106. Published
    Jellema, R. K., Ophelders, D. R. M. G., Zwanenburg, A., Nikiforou, M., Delhaas, T., Andriessen, P., ... Kramer, B. W. (2015). Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain. Journal of Neuroinflammation, 12, 241. https://doi.org/10.1186/s12974-015-0459-5
  107. 2016
  108. Published
    Hütten, M., Wolfs, T., & Kramer, B. (2016). Can the preterm lung recover from perinatal stress? Molecular and Cellular Pediatrics, 3(1), [15]. https://doi.org/10.1186/s40348-016-0043-9
  109. Published
    Nikiforou, M., Willburger, C., de Jong, A. E., Kloosterboer, N., Jellema, R. K., Ophelders, D. R. M. G., ... Wolfs, T. G. A. M. (2016). Global Hypoxia-Ischemia Induced Inflammation and Structural Changes in the Preterm Ovine Gut Which Were Not Ameliorated by Mesenchymal Stem Cell Treatment. Molecular Medicine, 22, 244-257. https://doi.org/10.2119/molmed.2015.00252
  110. Published
    Mueller, M., Wolfs, T., Schoeberlein, A., Gavilanes, A. D. W., Surbek, D., & Kramer, B. (2016). Mesenchymal stem/stromal cells—a key mediator for regeneration after perinatal morbidity? Molecular and Cellular Pediatrics, 3(1), [6]. https://doi.org/10.1186/s40348-016-0034-x
  111. Published
    Vanterpool, S., Tomsin, K., Reyes, L., Zimmermann, L., Kramer, B., & Been, J. (2016). Risk of adverse pregnancy outcomes in women with periodontal disease and the effectiveness of interventions in decreasing this risk: protocol for systematic overview of systematic reviews. Systematic Reviews, 5, [16]. https://doi.org/10.1186/s13643-016-0195-7
  112. Published
    Regan, J. K., Kannan, P. S., Kemp, M. W., Kramer, B. W., Newnham, J. P., Jobe, A. H., & Kallapur, S. G. (2016). Damage-Associated Molecular Pattern and Fetal Membrane Vascular Injury and Collagen Disorganization in Lipopolysaccharide-Induced Intra-amniotic Inflammation in Fetal Sheep. Reproductive Sciences, 23(1), 69-80. https://doi.org/10.1177/1933719115594014
  113. Published
    Nikiforou, M., Kemp, M. W., van Gorp, R., Saito, M., Newnham, J. P., Reynaert, N. L., ... Wolfs, T. (2016). Selective IL-1α exposure to the fetal gut, lung, and chorioamnion/skin causes intestinal inflammatory and developmental changes in fetal sheep. Laboratory Investigation, 96(1), 69-80. https://doi.org/10.1038/labinvest.2015.127
  114. Published
    Willems, M. G. M., Ophelders, D. R. M. G., Nikiforou, M., Jellema, R. K., Butz, A., Delhaas, T., ... Wolfs, T. G. A. M. (2016). Systemic interleukin-2 administration improves lung function and modulates chorioamnionitis-induced pulmonary inflammation in the ovine fetus. American Journal of Physiology-Lung Cellular and Molecular Physiology, 310(1), L1-L7. https://doi.org/10.1152/ajplung.00289.2015
  115. Published
    Vanterpool, S. F., Been, J. V., Houben, M. L., Nikkels, P. G. J., De Krijger, R. R., Zimmermann, L. J. I., ... Reyes, L. (2016). Porphyromonas gingivalis within Placental Villous Mesenchyme and Umbilical Cord Stroma Is Associated with Adverse Pregnancy Outcome. PLOS ONE, 11(1), [e0146157]. https://doi.org/10.1371/journal.pone.0146157
  116. Published
    Sparnaaij, M. A. R., Chedraui, P., Liem, K. H., Escobar, G. S., Espinoza-Caicedo, J., Kramer, B. W., ... Gavilanes, A. D. W. (2016). Fetal asphyctic preconditioning in rats results in a preserved placental inflammatory phenotype at birth. Placenta, 38, 84-92. https://doi.org/10.1016/j.placenta.2015.12.016
  117. Published
    Smit, A. L., Lambermont, V. A., Stokroos, R. J., Anteunis, L. J. C., Chenault, M., Schaefer, S. M., ... Kramer, B. W. (2016). Intrauterine Lipopolysaccharide-Induced Chorioamnionitis in a Sheep: Does It Affect the Auditory System? Reproductive Sciences, 23(2), 257-263. https://doi.org/10.1177/1933719115602759
  118. Published
    Ophelders, D. R. M. G., Gussenhoven, R., Lammens, M., Kusters, B., Kemp, M. W., Newnham, J. P., ... Wolfs, T. G. A. M. (2016). Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure. Journal of Neuroinflammation, 13, [29]. https://doi.org/10.1186/s12974-016-0492-z
  119. Published
    Peelen, M. J., Sheikh, A., Kok, M., Hajenius, P., Zimmermann, L. J., Kramer, B. W., ... Been, J. V. (2016). Tobacco control policies and perinatal health: a national quasi-experimental study. Scientific Reports, 6, [23907]. https://doi.org/10.1038/srep23907
  120. Published
    Seehase, M., Houthuizen, P., Collins, J. J. P., Zimmermann, L. J., & Kramer, B. W. (2016). Propofol administration to the fetal-maternal unit reduces cardiac oxidative stress in preterm lambs subjected to prenatal asphyxia and cardiac arrest. Pediatric Research, 79(5), 748-753. https://doi.org/10.1038/pr.2016.10
  121. Published
    Fabiano, A., Gavilanes, A. D. W., Zimmermann, L. J., Kramer, B. W. W., Paolillo, P., Livolti, G., ... Gazzolo, D. (2016). The development of lung biochemical monitoring can play a key role in the early prediction of bronchopulmonary dysplasia. Acta Paediatrica, 105(5), 535–541. https://doi.org/10.1111/apa.13233
  122. Published
    Zwanenburg, A., Hermans, B. J. M., Andriessen, P., Niemarkt, H. J., Jellema, R. K., Ophelders, D. R. M. G., ... Delhaas, T. (2016). Comparison of ECG-based physiological markers for hypoxia in a preterm ovine model. Pediatric Research, 79(6), 907-915. https://doi.org/10.1038/pr.2016.21
  123. Published
    Ophelders, D. R. M. G., Wolfs, T. G. A. M., Jellema, R. K., Zwanenburg, A., Andriessen, P., Delhaas, T., ... Kramer, B. W. (2016). Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia. Stem Cells Translational Medicine, 5(6), 754-763. https://doi.org/10.5966/sctm.2015-0197
  124. Published
    Nikiforou, M., Jacobs, E. M. R., Kemp, M. W., Hornef, M. W., Payne, M. S., Saito, M., ... Wolfs, T. G. A. M. (2016). Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine. Scientific Reports, 6, [29806]. https://doi.org/10.1038/srep29806
  125. Published
    Kemp, M. W., Saito, M., Usuda, H., Molloy, T. J., Miura, Y., Sato, S., ... Jobe, A. H. (2016). Maternofetal pharmacokinetics and fetal lung responses in chronically catheterized sheep receiving constant, low-dose infusions of betamethasone phosphate. American Journal of Obstetrics and Gynecology, 215(6), 775.e1-775.e12. https://doi.org/10.1016/j.ajog.2016.08.017
  126. Published
    van Ganzewinkel, C., Been, J. V., Dieleman, J. P., Katgert, T., Boelen-van der Loo, T., van der Pal, S. M., ... Andriessen, P. (2016). Pain coping strategies: Neonatal intensive care unit survivors in adolescence. Early Human Development, 103, 27-32. https://doi.org/10.1016/j.earlhumdev.2016.07.003
  127. 2017
  128. Published
    Shruthi, S., Sumitha, R., Varghese, A. M., Ashok, S., Sagar, B. K. C., Sathyaprabha, T. N., ... Alladi, P. A. (2017). Brain-Derived Neurotrophic Factor Facilitates Functional Recovery from ALS-Cerebral Spinal Fluid-Induced Neurodegenerative Changes in the NSC-34 Motor Neuron Cell Line. Neurodegenerative Diseases, 17(1), 44-58. https://doi.org/10.1159/000447559
  129. Published
    Niemarkt, H. J., Hutten, M. C., & Kramer, B. W. (2017). Surfactant for Respiratory Distress Syndrome: New Ideas on a Familiar Drug with Innovative Applications. Neonatology, 111(4), 408-414. https://doi.org/10.1159/000458466
  130. Published
    Peelen, M. J., Sheikh, A., Kok, M., Hajenius, P., Zimmermann, L., Kramer, B., ... Been, J. (2017). Tabaksontmoediging en perinatale gezondheid*. Nederlands Tijdschrift voor Geneeskunde, 1-6. [161:D563].
  131. Published
    Gussenhoven, R., Ophelders, D. R. M. G., Kemp, M. W., Payne, M. S., Spiller, O. B., Beeton, M. L., ... Wolfs, T. G. A. M. (2017). The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development. Developmental Neuroscience, 39(6), 472-486. https://doi.org/10.1159/000479021
  132. Published
    Kemp, M. W., Ahmed, S., Beeton, M. L., Payne, M. S., Saito, M., Miura, Y., ... Spiller, O. B. (2017). Foetal Ureaplasma parvum bacteraemia as a function of gestation-dependent complement insufficiency: Evidence from a sheep model of pregnancy. American Journal of Reproductive Immunology, 77(1), [12599]. https://doi.org/10.1111/aji.12599
  133. Published
    Mueller, M., Oppliger, B., Joerger-Messerli, M., Reinhart, U., Barnea, E., Paidas, M., ... Schoeberlein, A. (2017). Wharton's Jelly Mesenchymal Stem Cells Protect the Immature Brain in Rats and Modulate Cell Fate. Stem Cells and Development, 26(4), 239-248. https://doi.org/10.1089/scd.2016.0108
  134. Published
    De La Haye, N., Hütten, M. C., Kunzmann, S., & Kramer, B. W. (2017). Bronchopulmonary Dysplasia and Ureaplasma: What Do We Know So Far? . Neonatal Medicine, 24(1), 1-6. https://doi.org/10.5385/nm.2017.24.1.1
  135. Published
    Schmidt, A. F., Kemp, M. W., Kannan, P. S., Kramer, B. W., Newnham, J. R., Kallapur, S. G., & Jobe, A. H. (2017). Antenatal dexamethasone vs. betamethasone dosing for lung maturation in fetal sheep. Pediatric Research, 81(3), 496-503. https://doi.org/10.1038/pr.2016.249
  136. Published
    Rocha-Ferreira, E., Kelen, D., Faulkner, S., Broad, K. D., Chandrasekaran, M., Kerenyi, A., ... Robertson, N. J. (2017). Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model. Journal of Neuroinflammation, 14, [44]. https://doi.org/10.1186/s12974-017-0821-x
  137. Published
    Barkhuizen, M., van den Hove, D. L. A., Vles, J. S. H., Steinbusch, H. W. M., Kramer, B. W., & Gavilanes, A. W. D. (2017). 25 years of research on global asphyxia in the immature rat brain. Neuroscience and Biobehavioral Reviews, 75, 166-182. https://doi.org/10.1016/j.neubiorev.2017.01.042
  138. Published
    Willems, M. G. M., Kemp, M. W., Fast, L. A., Wagemaker, N. M. M., Janssen, L. E. W., Newnham, J. P., ... Wolfs, T. G. A. M. (2017). Pulmonary vascular changes in extremely preterm sheep after intra-amniotic exposure to Ureaplasma parvum and lipopolysaccharide. PLOS ONE, 12(6), [0180114]. https://doi.org/10.1371/journal.pone.0180114
  139. Published
    van Ganzewinkel, C. J. L. M., Been, J. V., Verbeek, I., van der Loo, T. B., van der Pal, S. M., Kramer, B. W., & Andriessen, P. (2017). Pain threshold, tolerance and intensity in adolescents born very preterm or with low birth weight. Early Human Development, 110, 31-38. https://doi.org/10.1016/j.earlhumdev.2017.05.001
  140. Published
    Schuller, S. S., Wisgrill, L., Herndl, E., Spittler, A., Forster-Waldl, E., Sadeghi, K., ... Berger, A. (2017). Pentoxifylline modulates LPS-induced hyperinflammation in monocytes of preterm infants in vitro. Pediatric Research, 82(2), 215-225. https://doi.org/10.1038/pr.2017.41
  141. Published
    Ricci, F., Salomone, F., Kuypers, E., Ophelders, D., Nikiforou, M., Willems, M., ... Bianco, F. (2017). In Vivo Evaluation of the Acute Pulmonary Response to Poractant Alfa and Bovactant Treatments in Lung-Lavaged Adult Rabbits and in Preterm Lambs with Respiratory Distress Syndrome. Frontiers in pediatrics, 5, [186]. https://doi.org/10.3389/fped.2017.00186
  142. Published
    Coelho, A. I., Bierau, J., Lindhout, M., Achten, J., Kramer, B. W., & Rubio-Gozalbo, M. E. (2017). Classic Galactosemia: Study on the Late Prenatal Development of GALT Specific Activity in a Sheep Model. The Anatomical Record: advances in integrative anatomy and evolutionary biology, 300(9), 1570-1575. https://doi.org/10.1002/ar.23616
  143. Published
    Berkhout, D. J. C., Niemarkt, H. J., Buijck, M., Van Weissenbruch, M. M., Brinkman, P., Benninga, M. A., ... de Meij, T. G. J. (2017). Detection of Sepsis in Preterm Infants by Fecal Volatile Organic Compounds Analysis: A Proof of Principle Study. Journal of Pediatric Gastroenterology and Nutrition, 65(3), E47-E52. https://doi.org/10.1097/MPG.0000000000001471
  144. Published
    Mueller, M., & Kramer, B. W. (2017). Stem cells and Bronchopulmonary Dysplasia - The five questions: Which cells, when, in which dose, to which patients via which route? Paediatric Respiratory Reviews, 24, 54-59. https://doi.org/10.1016/j.prrv.2016.12.003
  145. Published
    Villamor-Martinez, E., Pierro, M., Cavallaro, G., Mosca, F., Kramer, B., & Villamor, E. (2017). Probiotic Supplementation in Preterm Infants Does Not Affect the Risk of Bronchopulmonary Dysplasia: A Meta-Analysis of Randomized Controlled Trials. Nutrients, 9(11), [1197]. https://doi.org/10.3390/nu9111197
  146. Published
    Mishra, P-S., Vijayalakshmi, K., Nalini, A., Sathyaprabha, T. N., Kramer, B. W., Alladi, P. A., & Raju, T. R. (2017). Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia. Journal of Neuroinflammation, 14, [251]. https://doi.org/10.1186/s12974-017-1028-x
  147. 2018
  148. Published
    Rittenschober-Bohm, J., Rodger, J., Jobe, A. H., Kallapur, S. G., Doherty, D. A., Kramer, B. W., ... Kemp, M. W. (2018). Antenatal Corticosteroid Exposure Disrupts Myelination in the Auditory Nerve of Preterm Sheep. Neonatology, 114(1), 62-68. https://doi.org/10.1159/000487914
  149. Published
    Schmidt, A. F., Kemp, M. W., Rittenschober-Bohm, J., Kannan, P. S., Usuda, H., Saito, M., ... Jobe, A. H. (2018). Low-dose betamethasone-acetate for fetal lung maturation in preterm sheep. American Journal of Obstetrics and Gynecology, 218(1), 132.e1-132.e9. https://doi.org/10.1016/j.ajog.2017.11.560
  150. Published
    Berkhout, D. J. C., Klaassen, P., Niemarkt, H. J., de Boode, W. P., Cossey, V., van Goudoever, J. B., ... de Meij, T. G. J. (2018). Risk Factors for Necrotizing Enterocolitis: A Prospective Multicenter Case-Control Study. Neonatology, 114(3), 277-284. https://doi.org/10.1159/000489677
  151. Published
    Berkhout, D. J. C., Niemarkt, H. J., Benninga, M. A., Budding, A. E., van Kaam, A. H., Kramer, B. W., ... de Meij, T. G. J. (2018). Development of severe bronchopulmonary dysplasia is associated with alterations in fecal volatile organic compounds. Pediatric Research, 83(2), 412-419. https://doi.org/10.1038/pr.2017.268
  152. Published
    Villamor-Martinez, E., Pierro, M., Cavallaro, G., Mosca, F., Kramer, B. W., & Villamor, E. (2018). Donor Human Milk Protects against Bronchopulmonary Dysplasia: A Systematic Review and Meta-Analysis. Nutrients, 10(2), [238]. https://doi.org/10.3390/nu10020238
  153. Published
    van Sambeeck, S. J., Fuijkschot, J., Kramer, B. W., & Vos, G. D. (2018). Pediatric Early Warning System Scores: Lessons to be Learned. Journal of Pediatric Intensive Care, 7(1), 27-32. https://doi.org/10.1055/s-0037-1602802
  154. Published
    Andriessen, P., Zwanenburg, A., van Laar, J. O. E. H., Vullings, R., Hermans, B. J. M., Niemarkt, H. J., ... Delhaas, T. (2018). ST waveform analysis for monitoring hypoxic distress in fetal sheep after prolonged umbilical cord occlusion. PLOS ONE, 13(4), [e0195978]. https://doi.org/10.1371/journal.pone.0195978
  155. Published
    Gussenhoven, R., Westerlaken, R. J. J., Ophelders, D. R. M. G., Jobe, A. H., Kemp, M. W., Kallapur, S. G., ... Wolfs, T. G. A. M. (2018). Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus. Journal of Neuroinflammation, 15, [113]. https://doi.org/10.1186/s12974-018-1149-x
  156. Published
    Barkhuizen, M., van Dijck, F. J. P., Jellema, R. K., Gussenhoven, R., Engelbertink, I., van Mechele, R., ... Kramer, B. W. (2018). The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb. Pediatric Research, 83(6), 1190-1199. https://doi.org/10.1038/pr.2018.42
  157. Published
    Schueller, S. S., Kramer, B. W., Villamor, E., Spittler, A., Berger, A., & Levy, O. (2018). Immunomodulation to Prevent or Treat Neonatal Sepsis: Past, Present, and Future. Frontiers in pediatrics, 6, [199]. https://doi.org/10.3389/fped.2018.00199
  158. Published
    Sathyaprabha, T. N., Koot, L. A. M., Hermans, B. H. M., Adoor, M., Sinha, S., Kramer, B. W., ... Delhaas, T. (2018). Effects of Chronic Carbamazepine Treatment on the ECG in Patients with Focal Seizures. Clinical Drug Investigation, 38(9), 845-851. https://doi.org/10.1007/s40261-018-0677-6
  159. Published
    Barkhuizen, M., Rodrigues, F. B., Anderson, D. G., Winkens, B., REGISTRY Investigators European, Wild, E. J., ... Gavilanes, A. W. D. (2018). Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis. Parkinsonism & Related Disorders, 55, 55-60. https://doi.org/10.1016/j.parkreldis.2018.05.016
  160. Published
    Duc Ninh Nguyen, Thymann, T., Goericke-Pesch, S. K., Ren, S., Wei, W., Skovgaard, K., ... Sangild, P. T. (2018). Prenatal Intra-Amniotic Endotoxin Induces Fetal Gut and Lung Immune Responses and Postnatal Systemic Inflammation in Preterm Pigs. American Journal of Pathology, 188(11), 2629-2643. https://doi.org/10.1016/j.ajpath.2018.07.020
  161. Published
    Wahl, H. B., Hutten, M. C., Monz, D., Tutdibi, E., Ophelders, D., Nikiforou, M., ... Kramer, B. W. (2018). Vitamin A Supplementation by Endotracheal Application of a Nano-encapsulated Preparation Is Feasible in Ventilated Preterm Lambs. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 31(6), 323-330. [323-330]. https://doi.org/10.1089/jamp.2017.1438
  162. 2019
  163. Published
    el Hassani, S. E. M., Berkhout, D. J. C., Niemarkt, H. J., Mann, S., de Boode, W. P., Cossey, V., ... de Meij, T. G. J. (2019). Risk Factors for Late-Onset Sepsis in Preterm Infants: A Multicenter Case-Control Study. Neonatology, 116(1), 42-51. https://doi.org/10.1159/000497781
  164. Published
    Berkhout, D. J. C., van Keulen, B. J., Niemarkt, H. J., Bessem, J. R., de Boode, W. P., Cossey, V., ... de Meij, T. G. J. (2019). Late-onset Sepsis in Preterm Infants Can Be Detected Preclinically by Fecal Volatile Organic Compound Analysis: A Prospective, Multicenter Cohort Study. Clinical Infectious Diseases, 68(1), 70-77. https://doi.org/10.1093/cid/ciy383
  165. Published
    STOP-BPD Study Grp, Data Safety Monitoring Comm, Onland, W., Cools, F., Kroon, A., Rademaker, K., ... de Wildt, S. (2019). Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial. JAMA-Journal of the American Medical Association, 321(4), 354-363. https://doi.org/10.1001/jama.2018.21443
  166. Published
    Gussenhoven, R., Klein, L., Ophelders, D. R. M. G., Habets, D. H. J., Giebel, B., Kramer, B. W., ... Wolfs, T. G. A. M. (2019). Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy. Journal of Clinical Medicine, 8(2), [137]. https://doi.org/10.3390/jcm8020137
  167. Published
    Sumitha, R., Manjunatha, V. M., Sabitha, R. K., Alladi, P. A., Nalini, A., Rao, L. T., ... Raju, T. R. (2019). Cerebrospinal Fluid from Patients with Sporadic Amyotrophic Lateral Sclerosis Induces Degeneration of Motor Neurons Derived from Human Embryonic Stem Cells. Molecular Neurobiology, 56(2), 1014-1034. https://doi.org/10.1007/s12035-018-1149-y
  168. Published
    Barkhuizen, M., van Mechelen, R., Vermeer, M., Chedraui, P., Paes, D., van den Hove, D. L. A., ... Gavilanes, A. W. D. (2019). Systemic multipotent adult progenitor cells improve long-term neurodevelopmental outcomes after preterm hypoxic-ischemic encephalopathy. Behavioural Brain Research, 362, 77-81. https://doi.org/10.1016/j.bbr.2019.01.016
  169. Published
    van Gorp, C., de Lange, I. H., Spiller, O. B., Dewez, F., Pastor, B. C., Heeren, R. M. A., ... Wolfs, T. G. A. M. (2019). Protection of the Ovine Fetal Gut against Ureaplasma-Induced Chorioamnionitis: A Potential Role for Plant Sterols. Nutrients, 11(5), 1-21. [968]. https://doi.org/10.3390/nu11050968
  170. Published
    Bennis, F. C., van Pul, C., van den Bogaart, J. J. L., Andriessen, P., Kramer, B. W., & Delhaas, T. (2019). Artifacts in pulse transit time measurements using standard patient monitoring equipment. PLOS ONE, 14(6), [0218784]. https://doi.org/10.1371/journal.pone.0218784
  171. Published
    de Munter, J. P., Beugels, J., Munter, S., Jansen, L., Cillero-Pastor, B., Moskvin, O., ... Wolters, E. C. (2019). Standardized human bone marrow-derived stem cells infusion improves survival and recovery in a rat model of spinal cord injury. Journal of the Neurological Sciences, 402, 16-29. https://doi.org/10.1016/j.jns.2019.05.002
  172. Published
    van Sambeeck, S. J., van Kuijk, S. M. J., Kramer, B. W., Vermeulen, P. M., & Vos, G. D. (2019). Endotracheal intubation skills of pediatricians versus anesthetists in neonates and children. European Journal of Pediatrics, 178(8), 1219-1227. https://doi.org/10.1007/s00431-019-03395-8
  173. Published
    Beugels, J., Molin, D. G. M., Ophelders, D. R. M. G., Rutten, T., Kessels, L., Kloosterboer, N., ... Wolfs, T. G. A. M. (2019). Electrical stimulation promotes the angiogenic potential of adipose-derived stem cells. Scientific Reports, 9, [12076]. https://doi.org/10.1038/s41598-019-48369-w
  174. Published
    Delhaas, T., Andriessen, P., van Laar, J. O. E. H., Vullings, R., Hermans, B. J. M., Niemarkt, H. J., ... Zwanenburg, A. (2019). Why-aVF can be used in STAN as a proxy for scalp electrode-derived signal; reply to comments by Kjellmer et al. PLOS ONE, 14(8), [0221220]. https://doi.org/10.1371/journal.pone.0221220
  175. Published
    Polavarapu, K., Preethish-Kumar, V., Sekar, D., Vengalil, S., Nashi, S., Mahajan, N. P., ... Nalini, A. (2019). Mutation pattern in 606 Duchenne muscular dystrophy children with a comparison between familial and non-familial forms: a study in an Indian large single-center cohort. Journal of Neurology, 266(9), 2177-2185. https://doi.org/10.1007/s00415-019-09380-3
  176. Published
    Barkhuizen, M., Vles, J. S. H., van Mechelen, R., Vermeer, M., Kramer, B. W., Chedraui, P., ... Gavilanes, A. W. D. (2019). Preterm Perinatal Hypoxia-Ischemia Does not Affect Somatosensory Evoked Potentials in Adult Rats. Diagnostics, 9(3), [123]. https://doi.org/10.3390/diagnostics9030123
  177. Published
    Huetten, M. C., Fehrholz, M., Konrad, F. M., Ophelders, D., Kleintjes, C., Ottensmeier, B., ... Kunzmann, S. (2019). Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 32(6), 1-9. https://doi.org/10.1089/jamp.2019.1528

UM personal profile

UM postal address
P.O. Box 616
6200 MD Maastricht
The Netherlands

UM visiting address
Minderbroedersberg 4-6
6211 LK Maastricht
The Netherlands
Phone: +31 43 388 2222

Quick Links