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Researcher

Vreugdenhil, A.C.E.

Associate Professor, UMS

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  1. 2019
  2. Published
    Karnebeek, K., Thapar, S., Willeboordse, M., van Schayck, O. C. P., & Vreugdenhil, A. C. E. (2019). Comorbidities in Primary vs Secondary School Children With Obesity and Responsiveness to Lifestyle Intervention. Journal of Clinical Endocrinology & Metabolism, 104(9), 3803-3811. https://doi.org/10.1210/jc.2018-02318
  3. Published
    Drummen, M., Heinecke, A., Dorenbos, E., Vreugdenhil, A., Raben, A., Westerterp-Plantenga, M. S., & Adam, T. C. (2019). Reductions in body weight and insulin resistance are not associated with changes in grey matter volume or cortical thickness during the PREVIEW study. Journal of the Neurological Sciences, 403, 106-111. https://doi.org/10.1016/j.jns.2019.06.017
  4. Published
    Plat, J., Baumgartner, S., Vanmierlo, T., Luetjohann, D., Calkins, K. L., Burrin, D. G., ... Mensink, R. P. (2019). Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?". Progress in Lipid Research, 74, 87-102. https://doi.org/10.1016/j.plipres.2019.02.003
  5. Published
    van Dam, M., Rijks, J., Dorenbos, E., Horuz, F., van Dael, K., & Vreugdenhil, A. (2019). The effect of one year lifestyle intervention on eGFR in children and adolescents with overweight, obesity and morbid obesity. Scientific Reports, 9, 1-8. [4504]. https://doi.org/10.1038/s41598-019-40767-4
  6. Published
    Drummen, M., Dorenbos, E., Vreugdenhil, A. C. E., Raben, A., Westerterp-Plantenga, M. S., & Adam, T. C. (2019). Insulin resistance, weight, and behavioral variables as determinants of brain reactivity to food cues: a Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World a PREVIEW study. American Journal of Clinical Nutrition, 109(2), 315-321. https://doi.org/10.1093/ajcn/nqy252
  7. Published
    Roebroek, Y. G. M., Paulus, G. F., van Mil, E. G. A. H., Vreugdenhil, A. C. E., Winkens, B., Nederkoorn, C., ... van Heurn, L. W. E. (2019). Bariatric surgery in adolescents: a prospective randomized controlled trial comparing laparoscopic gastric banding to combined lifestyle interventions in adolescents with severe obesity (BASIC trial). Bmc Pediatrics, 19(1), [34]. https://doi.org/10.1186/s12887-019-1395-9
  8. Published
    Plat, J., Baumgartner, S., Vreugdenhil, A. C. E., Konings, M. C. J. M., Calkins, K. L., & Mensink, R. P. (2019). Modifying Serum Plant Sterol Concentrations: Effects on Markers for Whole Body Cholesterol Metabolism in Children Receiving Parenteral Nutrition and Intravenous Lipids. Nutrients, 11(1), 1-9. [120]. https://doi.org/10.3390/nu11010120
  9. 2018
  10. Published
    Mann, J. P., Vreugdenhil, A., Soch, P., Jariczyk, W., Baumann, U., Rajwal, S., ... Anstee, Q. M. (2018). European paediatric non-alcoholic fatty liver disease registry (EU-PNAFLD): Design and rationale. Contemporary Clinical Trials, 75, 67-71. https://doi.org/10.1016/j.cct.2018.11.003
  11. Published
    Rijks, J., Vreugdenhil, A., Dorenbos, E., Karnebeek, K., Joris, P., Berendschot, T., ... Plat, J. (2018). Characteristics of the retinal microvasculature in association with cardiovascular risk markers in children with overweight, obesity and morbid obesity. Scientific Reports, 8(1), 1-8. [16952]. https://doi.org/10.1038/s41598-018-35279-6
  12. Published
    Drummen, M., Dorenbos, E., Vreugdenhil, A. C. E., Stratton, G., Raben, A., Westerterp-Plantenga, M. S., & Adam, T. C. (2018). Associations of Brain Reactivity to Food Cues with Weight Loss, Protein Intake and Dietary Restraint during the PREVIEW Intervention. Nutrients, 10(11), [1771]. https://doi.org/10.3390/nu10111771
  13. Published
    Drummen, M., Dorenbos, E., Vreugdenhil, A. C. E., Raben, A., Fogelholm, M., Westerterp-Plantenga, M. S., & Adam, T. C. (2018). Long-term effects of increased protein intake after weight loss on intrahepatic lipid content and implications for insulin sensitivity: a PREVIEW study. American Journal of Physiology : Endocrinology and Metabolism, 315(5), E885-E891. https://doi.org/10.1152/ajpendo.00162.2018
  14. Published
    Plat, J., Baumgartner, S., Houben, T., Vreugdenhil, A. C. E., Mensink, R. P., Luetjohann, D., & Shiri-Sverdlov, R. (2018). Comment on Tauriainen et al. Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD. Bioscience Reports, 38, [20180505]. https://doi.org/10.1042/BSR20180505
  15. Published
    Zolotarjova, J., ten Velde, G., & Vreugdenhil, A. C. E. (2018). Effects of multidisciplinary interventions on weight loss and health outcomes in children and adolescents with morbid obesity. Obesity Reviews, 19(7), 931-946. https://doi.org/10.1111/obr.12680
  16. Published
    Kampshoff, C. S., van Dongen, J. M., van Mechelen, W., Schep, G., Vreugdenhil, A., Twisk, J. W. R., ... Buffart, L. M. (2018). Long-term effectiveness and cost-effectiveness of high versus low-to-moderate intensity resistance and endurance exercise interventions among cancer survivors. Journal of Cancer Survivorship-Research and Practice, 12(3), 417-429. https://doi.org/10.1007/s11764-018-0681-0
  17. Published
    Dorenbos, E., Drummen, M., Rijks, J., Adam, T., Stouthart, P., Martinez, J. A., ... Vreugdenhil, A. (2018). PREVIEW (Prevention of Diabetes Through Lifestyle Intervention and Population Studies in Europe and Around the World) study in children aged 10 to 17 years: Design, methods and baseline results. Diabetes Obesity & Metabolism, 20(5), 1096-1101. https://doi.org/10.1111/dom.13216
  18. 2017
  19. Published
    Plat, J., & Vreugdenhil, A. C. E. (2017). Response to Letter to the Editor: "Association of TSH With Cardiovascular Disease Risk in Overweight and Obese Children During Lifestyle Intervention". Journal of Clinical Endocrinology & Metabolism, 102(12), 4660-4661. https://doi.org/10.1210/jc.2017-01894
  20. Published
    Adriaanse, M. P. M., Mubarak, A., Riedl, R. G., Ten Kate, F. J. W., Damoiseaux, J. G. M. C., Buurman, W. A., ... Celiac Dis Study Grp (2017). Progress towards non-invasive diagnosis and follow-up of celiac disease in children; a prospective multicentre study to the usefulness of plasma I-FABP. Scientific Reports, 7, [8671]. https://doi.org/10.1038/s41598-017-07242-4
  21. Published
    Rijks, J. M., Plat, J., Dorenbos, E., Penders, B., Gerver, W-J. M., & Vreugdenhil, A. C. E. (2017). Association of TSH With Cardiovascular Disease Risk in Overweight and Obese Children During Lifestyle Intervention. Journal of Clinical Endocrinology & Metabolism, 102(6), 2051-2058. https://doi.org/10.1210/jc.2016-3057
  22. 2016
  23. Published
    Walenbergh, S. M. A., Houben, T., Rensen, S. S., Bieghs, V., Hendrikx, T., van Gorp, P. J., ... Shiri-Sverdlov, R. (2016). Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention. Scientific Reports, 6, [38278]. https://doi.org/10.1038/srep38278
  24. Published
    Adriaanse, M. P. M., Vreugdenhil, A. C. E., Vastmans, V., Groeneveld, L., Molenbroeck, S., Schott, D. A., ... Tilanus, M. G. J. (2016). Human leukocyte antigen typing using buccal swabs as accurate and non-invasive substitute for venipuncture in children at risk for celiac disease. Journal of Gastroenterology and Hepatology, 31(10), 1711-1716. https://doi.org/10.1111/jgh.13331
  25. Published
    Rijks, J., Karnebeek, K., van Dijk, J-W., Dorenbos, E., Gerver, W., Stouthart, P., ... Vreugdenhil, A. (2016). Glycaemic Profiles of Children With Overweight and Obesity in Free-living Conditions in Association With Cardiometabolic Risk. Scientific Reports, 6, [31892]. https://doi.org/10.1038/srep31892
  26. Published
    Rijks, J., Penders, B., Dorenbos, E., Straetemans, S., Gerver, W., & Vreugdenhil, A. (2016). Pituitary response to thyrotropin releasing hormone in children with overweight and obesity. Scientific Reports, 6, [31032]. https://doi.org/10.1038/srep31032
  27. Published
    Adriaanse, M. P. M., Leffler, D. A., Kelly, C. P., Schuppan, D., Najarian, R. M., Goldsmith, J. D., ... Vreugdenhil, A. C. E. (2016). Serum I-FABP Detects Gluten Responsiveness in Adult Celiac Disease Patients on a Short-Term Gluten Challenge. American Journal of Gastroenterology, 111(7), 1014-1022. https://doi.org/10.1038/ajg.2016.162
  28. Published
    Brüll, F., de Smet, E., Mensink, R. P., Vreugdenhil, A., Kerksiek, A., Lutjohann, D., ... Plat, J. (2016). Dietary plant stanol ester consumption improves immune function in asthma patients: results of a randomized, double-blind clinical trial. American Journal of Clinical Nutrition, 103(2), 444-453. https://doi.org/10.3945/ajcn.115.117531
  29. 2015
  30. Published
    Werthmann, J., Jansen, A., Vreugdenhil, A. C. E., Nederkoorn, C., Schyns, G., & Roefs, A. (2015). Food through the child's eye: an eye-tracking study on attentional bias for food in healthy-weight children and children with obesity. Health Psychology, 34(12), 1123-1132. https://doi.org/10.1037/hea0000225
  31. Published
    Adriaanse, M. P. M., van der Sande, L. J. T. M., van den Neucker, A. M., Menheere, P. P. C. A., Dompeling, E., Buurman, W. A., & Vreugdenhil, A. C. E. (2015). Evidence for a Cystic Fibrosis Enteropathy. PLOS ONE, 10(10), [e0138062]. https://doi.org/10.1371/journal.pone.0138062
  32. Published
    Rijks, J. M., Plat, J., Mensink, R. P., Dorenbos, E., Buurman, W. A., & Vreugdenhil, A. C. (2015). Children With Morbid Obesity Benefit Equally as Children With Overweight and Obesity From an Ongoing Care Program. Journal of Clinical Endocrinology & Metabolism, 100(9), 3572-3580. https://doi.org/10.1210/jc.2015-1444
  33. Published
    Dorenbos, E., Rijks, J. M., Adam, T. C., Westerterp-Plantenga, M. S., & Vreugdenhil, A. C. (2015). Sleep efficiency as a determinant of insulin sensitivity in overweight and obese adolescents. Diabetes Obesity & Metabolism, 17, 90-98. https://doi.org/10.1111/dom.12515
  34. Published
    te Velde, A. A., Brüll, F., Heinsbroek, S. E., Meijer, S. L., Lutjohann, D., Vreugdenhil, A., & Plat, J. (2015). Effects of Dietary Plant Sterols and Stanol Esters with Low- and High-Fat Diets in Chronic and Acute Models for Experimental Colitis. Nutrients, 7(10), 8518-8531. https://doi.org/10.3390/nu7105412
  35. Published
    Adriaanse, M. P., Buurman, W., & Vreugdenhil, A. C. (2015). Letter: serum I-FABP as marker for enterocyte damage in first-degree relatives of patients with coeliac disease - authors' reply. Alimentary Pharmacology & Therapeutics, 42(1), 122. https://doi.org/10.1111/apt.13240
  36. Published
    Walenbergh, S. M., Houben, T., Hendrikx, T., Jeurissen, M. L. J., van Gorp, P. J., Vreugdenhil, A. C., ... Shiri-Sverdlov, R. (2015). Plasma cathepsin d levels: a novel tool to predict pediatric hepatic inflammation. American Journal of Gastroenterology, 110(3), 462-470. https://doi.org/10.1038/ajg.2015.29
  37. Published
    Gross, S., Adriaanse, M. P., Nijeboer, P., Tack, G. J., van Hoogstraten, I. M., Bouma, G., ... Bontkes, H. J. (2015). Serum intestinal-fatty acid binding protein as a biomarker for refractory celiac disease. Journal of Gastrointestinal and Liver Diseases, 24(2), 258-259.
  38. 2014
  39. Published
    Vreugdenhil, A. C. (2014). Hepatitis. In Werkboek KinderMDL Amsterdam: VU Boekhandel / UItgeverij BV.
  40. Published
    Adriaanse, M. P., Vreugdenhil, A. C., Groeneweg, M., Bruggenwirth, H. T., Castelijns, S. J., van der Ent, C. K., ... Tilanus, M. G. (2014). HLA frequencies and associations in cystic fibrosis. Tissue Antigens, 83(1), 27-31. https://doi.org/10.1111/tan.12265
  41. Published
    De Ridder, L., Turner, D., Wilson, D. C., Koletzko, S., Martin-de-Carpi, J., Fagerberg, U. L., ... Porto IBD Working Group of ESPGHAN incl. Vreugdenhil, A. (2014). Malignancy and mortality in pediatric patients with inflammatory bowel disease: a multinational study from the porto pediatric IBD group. Inflammatory Bowel Diseases, 20(2), 291-300. https://doi.org/10.1097/01.MIB.0000439066.69340.3c
  42. Published
    Vreugdenhil, A. (2014). Pancreasaandoeningen. In Werkboek KinderMDL VU Boekhandel / UItgeverij BV.
  43. Published
    Plat, J., Hendrikx, T., Bieghs, V., Jeurissen, M. L. J., Walenbergh, S. M., van Gorp, P. J., ... Shiri-Sverdlov, R. (2014). Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans. PLOS ONE, 9(10), [e110758]. https://doi.org/10.1371/journal.pone.0110758
  44. 2013
  45. Published
    Tack, G. J., van de Water, J. M., Bruins, M. J., Kooy-Winkelaar, E. M., van Bergen, J., Bonnet, P., ... Koning, F. (2013). Consumption of gluten with gluten-degrading enzyme by celiac patients: A pilot-study. World Journal of Gastroenterology, 19(35), 5837-5847. https://doi.org/10.3748/wjg.v19.i35.5837
  46. Published
    de Betue, C. T. I., Joosten, K. F., Deutz, N. E., Vreugdenhil, A. C., & van Waardenburg, D. A. (2013). Arginine appearance and nitric oxide synthesis in critically ill infants can be increased with a protein-energy-enriched enteral formula. American Journal of Clinical Nutrition, 98(4), 907-916. https://doi.org/10.3945/ajcn.112.042523
  47. Published
    Adriaanse, M. P. M., Tack, G. J., Passos, V. L., Damoiseaux, J. G., Schreurs, M. W. J., van Wijck, K., ... Vreugdenhil, A. C. E. (2013). Serum I-FABP as marker for enterocyte damage in coeliac disease and its relation to villous atrophy and circulating autoantibodies. Alimentary Pharmacology & Therapeutics, 37(4), 482-490. https://doi.org/10.1111/apt.12194
  48. 2012
  49. Published
    Ras, J. E., Vreugdenhil, A. C., Houwen, R. H. J., & van den Neucker, A. M. (2012). Zijn we tevreden met één diagnose? Tijdschrift voor Kindergeneeskunde, 3, 66-70. https://doi.org/10.1007/s12456-012-0020-8
  50. 2011
  51. Published
    Vreugdenhil, A. C. E., Wolters, V. M., Adriaanse, M. P., van den Neucker, A. M., van Bijnen, A. A., Houwen, R., & Buurman, W. A. (2011). Additional value of serum i-fabp levels for evaluating celiac disease activity in children. Scandinavian Journal of Gastroenterology, 46(12), 1435-1441. https://doi.org/10.3109/00365521.2011.627447
  52. Published
    De Bie, C. I., Hummel, T. Z., Kindermann, A., Kokke, F. T., Damen, G. M., Kneepkens, C. M., ... De Ridder, L. (2011). The duration of effect of infliximab maintenance treatment in paediatric Crohn's disease is limited. Alimentary Pharmacology & Therapeutics, 33(2), 243-250. https://doi.org/10.1111/j.1365-2036.2010.04507.x
  53. 2010
  54. Published
    Vreugdenhil, A. C. E., van Mil, E. G., & van Heurn, L. W. E. (2010). Een extreem dik kind: is operatieve behandeling wenselijk? In Praktische Pediatrie, Nr. 2
  55. 2009
  56. Published
    Derikx, J. P., Vreugdenhil, A. C. E., van den Neucker, A. M., Grootjans, J., van Bijnen, A. A., Damoiseaux, J. G. M. C., ... Buurman, W. A. (2009). A pilot study on the noninvasive evaluation of intestinal damage in celiac disease using I-FABP and L-FABP. Journal of Clinical Gastroenterology, 43(8), 727-733. https://doi.org/10.1097/MCG.0b013e31819194b0
  57. 2007
  58. Published
    De Backer, I. C., van Breda, E., Vreugdenhil, A. C. E., Nijziel, M. R., Kester, A. D. M., & Schep, G. (2007). High-intensity strength training improves quality of life in cancer survivors. Acta Oncologica, 46(8), 1143-1151. https://doi.org/10.1080/02841860701418838
  59. 2004
  60. Published
    Luyer, M. D. P., Jacobs, J. A., Vreugdenhil, A. C. E., Hadfoune, M., Dejong, C. H., Buurman, W. A., & Greve, J. W. (2004). Enteral administration of high-fat nutrition before and directly after hemorrhagic shock reduces endotoxemia and bacterial translocation. Annals of Surgery, 239(2), 257-264. https://doi.org/10.1097/01.sla.0000108695.60059.80
  61. 2003
  62. Published
    Vreugdenhil, A. C. E. (2003). Intestinal defense against bacterial toxins : role of LPS binding protein and lipoproteins. [Maastricht: Universitaire Pers Maastricht.
  63. Published
    Vreugdenhil, A. C. E., Rousseau, C. H., Hartung, T., Greve, J. W. M., van 't Veer, C., & Buurman, W. A. (2003). Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicrons. Journal of Immunology, 170(3), 1399-1405. https://doi.org/10.4049/jimmunol.170.3.1399
  64. 2001
  65. Published
    Vreugdenhil, A. C. E., Snoek, A. M. P., van 't Veer, C., Greve, J. W. M., & Buurman, W. A. (2001). LPS-binding protein circulates in association with apoB-containing lipoproteins and enhances endotoxin-LDL/VLDL interaction. Journal of Clinical Investigation, 107, 225-234. https://doi.org/10.1172/JCI10832
  66. 2000
  67. Published
    Scott, M. G., Vreugdenhil, A. C. E., Buurman, W. A., Hancock, R. E., & Gold, M. R. (2000). Cutting edge: cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein. Journal of Immunology, 164, 549-553. https://doi.org/10.4049/jimmunol.164.2.549
  68. Published
    Vreugdenhil, A. C. E., Snoek, A. M. P., Greve, J. W. M., & Buurman, W. A. (2000). Lipopolysaccharide-binding protein is vectorially secreted and transported by cultured intestinal epithelial cells and is present in the intestinal mucus of mice. Journal of Immunology, 165, 4561-4566. https://doi.org/10.4049/jimmunol.165.8.4561
  69. Published
    Dentener, M. A., Vreugdenhil, A. C. E., Hoet, P. H., Vernooy, J. H. J., Nieman, F. H. M., Heumann, D., ... Wouters, E. F. M. (2000). Production of the acute-phase protein lipopolysaccharide-binding protein by respiratory type II epithelial cells: implications for local defense to bacterial endotoxins. American Journal of Respiratory Cell and Molecular Biology, 23, 146-153. https://doi.org/10.1165/ajrcmb.23.2.3855
  70. 1999
  71. Published
    Vreugdenhil, A. C. E., Dentener, M. A., Snoek, A. M. P., Greve, J. W. M., & Buurman, W. A. (1999). Lipopolysaccharide binding protein and serum amyloid A secretion by human intestinal epithelial cells during the acute phase response. Journal of Immunology, 163(5), 2792-2798.

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