
Researcher
Bast, A.
Full professor - Key domain chair
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- 1998
- PublishedKarsdorp, V. H. M., Dekker, G. A., Bast, A., van Kamp, G. J., Bouman, A. A., van Vugt, J. M. G., & van Geijn, H. P. (1998). Maternal and fetal plasma concentrations of endothelin, lipidhydroperoxides, glutathione peroxidase and fibronectin in relation to abnormal umbilical artery velocimetry. European Journal of Obstetrics & Gynecology and Reproductive Biology, 80(1), 39-44. https://doi.org/10.1016/S0301-2115(98)00079-7
- PublishedHoof, H. J. M., Zijlstra, F. J., Voss, H. P., Tak, C. J. A. M., van Bree, L., & Bast, A. (1998). The role of prostanoids in ozone-induced changes in airway responsiveness: receptor activation-specific prostanoid release. Environmental Toxicology and Pharmacology, 5(1), 69-78. https://doi.org/10.1016/S1382-6689(97)10063-1
- PublishedPennings, H. J., Kramer, K., Bast, A., Buurman, W. A., & Wouters, E. F. M. (1998). Tumour necrosis factor-alpha induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro. European Respiratory Journal, 12(1), 45-49. https://doi.org/10.1183/09031936.98.12010045
- 1999
- Publishedvan den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (1999). Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures. Food Chemistry, 66(4), 511-518. https://doi.org/10.1016/S0308-8146(99)00089-8
- Published
- PublishedPaquay, J. B. G., Hoen, P. A., Bast, A., Timmerman, H., & Haenen, G. R. M. M. (1999). Nitric oxide synthase inhibition by dimaprit and dimaprit analogues. British Journal of Pharmacology, 127(2), 331-334. https://doi.org/10.1038/sj.bjp.0702552
- PublishedBast, A. (1999). Van voorproever tot toxicoloog. Maastricht: Universiteit Maastricht. https://doi.org/10.26481/spe.19991203ab
- 2000
- Publishedvan Acker, F. A. A., van Acker, S. A. B. E., Kramer, K., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2000). 7-monohydroxyethylrutoside protects against chronic doxorubicin-induced cardiotoxicity when administered only once per week. Clinical Cancer Research, 6, 1337-1347.
- PublishedDrent, M., Bomans, P. H. H., van Suylen, R. J., Lamers, R. J. S., Bast, A., & Wouters, E. F. M. (2000). Association of man-made mineral fibre exposure and sarcoidlike granulomas. Respiratory Medicine, 94(8), 815-820. https://doi.org/10.1053/rmed.2000.0827
- PublishedHeunks, L. M. A., Bast, A., van Herwaarden, C. L. A., Haenen, G. R. M. M., & Dekhuijzen, P. N. R. (2000). Effects of emphysema and training on glutathione oxidation in the hamster diaphragm. Journal of Applied Physiology, 88, 2054-2061. https://doi.org/10.1152/jappl.2000.88.6.2054
- Publishedvan Acker, F. A. A., Schouten, O., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2000). Flavonoids can replace alpha-tocopherol as an antioxidant. Febs Letters, 473, 145-148. https://doi.org/10.1016/S0014-5793(00)01517-9
- Publishedvan Acker, F. A. A., van Acker, S. A. B. E., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2000). In vitro screening of antitumour agents for cardiotoxicity by means of isolated mouse left atria. Anticancer Research, 20, 4483-4488.
- PublishedWesterveld, G. J., Voss, H. P., van der Hee, R. M., de Haan-Koelewijn, G. J. N., den Hartog, G. J. M., Scheeren, R. A., & Bast, A. (2000). Inhibition of nitric oxide synthase by nasal decongestants. European Respiratory Journal, 16, 437-444. https://doi.org/10.1034/j.1399-3003.2000.016003437.x
- PublishedPaquay, J. B. G., Haenen, G. R. M. M., Stender, G., Wiseman, S. A., Tijburg, L. B. M., & Bast, A. (2000). Protection against nitric oxide toxicity by tea. Journal of Agricultural and Food Chemistry, 48, 5768-5772. https://doi.org/10.1021/jf981316h
- PublishedRhemrev, J. P. T., van Overveld, F. W. P. C., Haenen, G. R. M. M., Teerlink, T., Bast, A., & Vermeiden, J. P. W. (2000). Quantification of the nonenzymatic fast and slow TRAP in a postaddition assay in human seminal plasma and the antioxidant contributions of various seminal compounds. Journal of Andrology, 21, 913-920.
- PublishedVreman, H. J., Haenen, G. R. M. M., Stevenson, D. K., & Bast, A. (2000). Reduction of the NO-mediated response in the rat aorta by metalloporphyrins. Canadian Journal of Physiology and Pharmacology, 78, 457-461. https://doi.org/10.1139/y00-009
- PublishedAbou el Hassan, M. A., Touw, D. J., Wilhelm, A. J., Bast, A., & van der Vijgh, W. J. F. (2000). Stability of monoHER in an aqueous formulation for i.v. administration. International Journal of Pharmaceutics, 15(211), 51-56. https://doi.org/10.1016/S0378-5173(00)00587-1
- PublishedYstby, O. B., Dalhus, B., Gundersen, L. L., Rise, F., Bast, A., & Haenen, G. R. M. M. (2000). Synthesis of 1-substituted 7-cyano-2,3-diphenylindolizines and evaluation of antioxidant properties. European Journal of Organic Chemistry, 3763-3770. https://doi.org/10.1002/1099-0690(200011)2000:22<3763::AID-EJOC3763>3.0.CO;2-S
- Publishedvan Acker, F. A. A., Hageman, G. J., Haenen, G. R. M. M., van der Vijgh, W. J. F., Bast, A., & Menge, W. M. P. B. (2000). Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity. Journal of Medicinal Chemistry, 43, 3752-3760. https://doi.org/10.1021/jm000951n
- Publishedvan den Berg, R., Haenen, G. R. M. M., van den Berg, H., van der Vijgh, W. J. F., & Bast, A. (2000). The predictive value of the antioxidant capacity of structurally related flavonoids using the Trolox equivalent antioxidant capacity TEAC assay. Food Chemistry, 70, 391-395. https://doi.org/10.1016/S0308-8146(00)00092-3
- PublishedVliet, L. A., Rodenhuis, N., Wikstrom, H., Pugsley, T. A., Serpa, K. A., Meltzer, L. T., ... Bast, A. (2000). Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists. Journal of Medicinal Chemistry, 43, 3549-3557. https://doi.org/10.1021/jm000087z
- Publishedvan Overveld, F. W. P. C., Haenen, G. R. M. M., Rhemrev, J. P. T., Vermeiden, J. P. W., & Bast, A. (2000). Tyrosine as important contributor to the antioxidant capacity of seminal plasma. Chemico-Biological Interactions, 127, 151-161. https://doi.org/10.1016/S0009-2797(00)00179-4
- 2001
- Publishedvan den Berg, R., van Vliet, T., Broekmans, W. M. R., Cnubben, N. H. P., Vaes, W. H. J., Roza, L., ... van den Berg, H. (2001). A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers. Journal of Nutrition, 131, 1714-1722. https://doi.org/10.1093/jn/131.6.1714
- Published
- PublishedKnaapen, A. M., den Hartog, G. J. M., Bast, A., & Borm, P. J. A. (2001). Ambient particulate matter induces relaxation of rat aortic rings in vitro. Human & Experimental Toxicology, 20(5), 259-265. https://doi.org/10.1191/096032701678227677
- PublishedMeijer, E. P., Goris, A. H. C., Senden, J. M. G., Dongen, J., & Bast, A. (2001). Antioxidant supplementation and exercise-induced oxidative stress in the 60-year-old as measured by antipyrine hydroxylates. British Journal of Nutrition, 86, 569-575. https://doi.org/10.1079/BJN2001434
- PublishedMeijer, E. P., Coolen, S. A. J., Bast, A., & Westerterp, K. R. (2001). Exercise training and oxidative stress in the elderly as measured by antipyrine hydroxylation products. Free Radical Research, 35, 435-443. https://doi.org/10.1080/10715760100300951
- PublishedMeijer, E. P., Coolen, S. A. J., Bast, A., & Westerterp, K. R. (2001). Exercise-induced oxidative stress in older adults as measured by antipyrine oxidation. Metabolism-Clinical and Experimental, 50(12), 1484-1488. https://doi.org/10.1053/meta.2001.28086
- PublishedBeerens - Heijnen, C. G. M., Haenen, G. R. M. M., van Acker, F. A. A., van der Vijgh, W. J. F., & Bast, A. (2001). Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups. Toxicology in Vitro, 15, 3-6. https://doi.org/10.1016/S0887-2333(00)00053-9
- PublishedEl Hassan, M., Kedde, M., Bast, A., & van der Vijgh, W. J. F. (2001). High-performance liquid chromatography with electrochemical detection for the determination of 7-monohydroxyethylrutoside in plasma. Journal of Chromatography B, 752, 115-121. https://doi.org/10.1016/S0378-4347(00)00532-6
- Published
- Publishedvan Haaften, R. I. M., Evelo, C. T. A., Penders, J., Eijnwachter, M., Haenen, G. R. M. M., & Bast, A. (2001). Inhibition of human glutathione S-transferase P1-1 by tocopherols and alpha-tocopherol derivatives. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1548, 23-28. https://doi.org/10.1016/S0167-4838(01)00211-4
- PublishedNemery, B., Bast, A., Behr, J., Borm, P. J. A., Bourke, S., Camus, P., ... Saltini, C. (2001). Interstitial lung disease induced by exogenous agents: factors governing susceptibility. European Respiratory Journal, 18 supp 12, 30s-42s.
- PublishedBast, A., & Haenen, G. R. M. M. (2001). Lipoic acid: A multifunctional nutraceutical. In K. Kramer, PP. Hoppe, & L. Packer (Eds.), Nutraceuticals in health and disease prevention New York / Basel: Marcel Dekker Inc..
- PublishedArts, M. J. T. J., Haenen, G. R. M. M., Voss, H. P., & Bast, A. (2001). Masking of antioxidant capacity by the interaction of flavonoids with protein. Food and Chemical Toxicology, 39, 787-791. https://doi.org/10.1016/S0278-6915(01)00020-5
- Publishedvan Acker, F. A. A., Hulshof, J., Haenen, G. R. M. M., Menge, W. M. P. B., van der Vijgh, W. J. F., & Bast, A. (2001). New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity. Free Radical Biology and Medicine, 31, 31-37. https://doi.org/10.1016/S0891-5849(01)00546-9
- PublishedDrent, M., van den Berg, R., Haenen, G. R. M. M., van den Berg, H., Wouters, E. F. M., & Bast, A. (2001). NF-kappaB activation in sarcoidosis. Sarcoidosis Vasculitis and Diffuse Lung Diseases, 18, 50-56.
- Published
- Publishedvan den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (2001). Nuclear factor-kappaB activation is higher in peripheral blood mononuclear cells of male smokers. Environmental Toxicology and Pharmacology, 9, 147-151. https://doi.org/10.1016/S1382-6689(00)00070-3
- PublishedBeerens - Heijnen, C. G. M., Haenen, G. R. M. M., Vekemans, J., & Bast, A. (2001). Peroxynitrite scavenging of flavonoids: structure activity relationship. Environmental Toxicology and Pharmacology, 10, 199-206. https://doi.org/10.1016/S1382-6689(01)00083-7
- PublishedRhemrev, J. P. T., Vermeiden, J. P. W., Haenen, G. R. M. M., de Bruijne, J., Rekers-Mombarg, L., & Bast, A. (2001). Progressively motile human spermatozoa are well protected against in vitro lipid peroxidation imposed by induced oxidative stress. Andrologia, 33, 151-158. https://doi.org/10.1046/j.1439-0272.2001.00430.x
- PublishedMohren, D. C. L., Swaen, G. M. H., Borm, P. J. A., Bast, A., & Galama, J. M. D. (2001). Psychological job demands as a risk factor for common cold in a Dutch working population. Journal of Psychosomatic Research, 50, 21-27. https://doi.org/10.1016/S0022-3999(00)00212-9
- PublishedOstby, O. B., Gundersen, L. L., Rise, F., Antonson, O., Fosnes, K., Larsen, V., ... Haenen, G. R. M. M. (2001). Synthesis of 5-substituted pyrrolo[1,2-b]pyridazines with antioxidant properties. Archiv der Pharmazie, 334, 21-24. https://doi.org/10.1002/1521-4184(200101)334:1<21::AID-ARDP21>3.0.CO;2-W
- Publishedvan den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (2001). Transcription factor NF-kappaB as a potential biomarker for oxidative stress. British Journal of Nutrition, 86 suppl 1, S121-S127. https://doi.org/10.1079/BJN2001340
- 2002
- PublishedStahl, W., van den Berg, H., Arthur, J., Bast, A., Dainty, J., Faulks, R. M., ... et, A. (2002). Bioavailability and metabolism. Molecular Aspects of Medicine, 23(1-3), 39-100. https://doi.org/10.1016/S0098-2997(02)00016-X
- PublishedGriffiths, H. R., Moller, L., Bartosz, G., Bast, A., Bertoni-Freddari, C., Collins, A., ... Verhagen, H. (2002). Biomarkers. Molecular Aspects of Medicine, 23(1-3), 101-108. https://doi.org/10.1016/S0098-2997(02)00017-1
- PublishedBast, A., Chandler, R. F., Choy, P. C., Delmulle, L. M., Gruenwald, J., Halkes, S. B. A., ... Vermeer, I. T. M. (2002). Botanical health products, positioning and requirements for effective and safe use. Environmental Toxicology and Pharmacology, 12, 195-211. https://doi.org/10.1016/S1382-6689(02)00035-2
- PublishedRothkrantz-Kos, S., Drent, M., Vuil, H., de Boer, M., Bast, A., Wouters, E. F. M., ... van Dieijen-Visser, M. P. (2002). Decreased redox state in red blood cells from patients with sarcoidosis. Sarcoidosis Vasculitis and Diffuse Lung Diseases, 19(2), 114-120.
- Publishedvan Schooten, F. J., Besarati Nia, A., de Flora, S., D'Agostini, F., Izzotti, A., Camoirano, A., ... et, A. (2002). Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers. Cancer Epidemiology Biomarkers & Prevention, 11(2), 167-175.
- Publishedden Hartog, G. J., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F., & Bast, A. (2002). Efficacy of HOCI scavenging by sulfurcontaining compounds: antioxidant activity of glutathione disulfide? Biological Chemistry, 383, 709-713.