TY - JOUR
T1 - "Yes, I'm interested in taking PrEP!"
T2 - PrEP interest among women respondents to the European community-based survey "Flash! PrEP in Europe"
AU - Delabre, Rosemary M
AU - Bernier, Adeline
AU - Sánchez, Flor
AU - Vilotitch, Antoine
AU - Chanos, Sophocles
AU - Cosmaro, Maria Luisa
AU - Langanke, Harriet
AU - Mey, Coline
AU - James, Cary
AU - Duken, Sascha B
AU - Schlegel, Vincent
AU - Stranz, Richard
AU - Jonas, Kai J.
AU - Spire, Bruno
AU - Rojas Castro, Daniela
PY - 2021/2/17
Y1 - 2021/2/17
N2 - The World Health Organization recommends pre-exposure prophylaxis (PrEP) for all populations at substantial risk of HIV infection, including women. However, data regarding PrEP interest among women is lacking, particularly in Europe. Factors associated with interest in using PrEP were assessed among women respondents to the Flash! PrEP in Europe (FPIE) survey. This community-based cross-sectional study, conducted in 12 European countries, aimed to assess PrEP knowledge and interest. "High objective risk" (HOR) was assessed using established risk criteria following EACS and CDC guidelines. Factors associated with interest in using PrEP were assessed in univariable and multivariable logistic regression models. Among 678 women, 12.5% (n = 85) were considered at HOR, 46.8% (n = 317) indicated prior PrEP knowledge and 18.0% (n = 122) reported interest in using PrEP. Among women at HOR, 40.0% (n = 34) were interested in PrEP. Factors significantly associated with PrEP interest in the final multivariable model were: younger age (18-29 years) (aOR 1.91[95CI: 1.07; 3.41]), bad self-perceived financial status (1.84[1.09; 3.11]), migrant status (south to north) (2.87[1.05; 7.89]), single or dating relationship status (1.93[1.23; 3.03]), sexual abuse history (1.86[1.17; 2.97]), "rather high"/ "high" self-perceived HIV risk (3.21[1.32; 7.81]), and HOR (2.49[1.42; 4.35]). These results show that women at HOR and those who perceived themselves to be at high risk are interested in using PrEP. There is a critical need for targeted information and improved access to PrEP to increase uptake of this HIV prevention tool to meet PrEP interest among women.
AB - The World Health Organization recommends pre-exposure prophylaxis (PrEP) for all populations at substantial risk of HIV infection, including women. However, data regarding PrEP interest among women is lacking, particularly in Europe. Factors associated with interest in using PrEP were assessed among women respondents to the Flash! PrEP in Europe (FPIE) survey. This community-based cross-sectional study, conducted in 12 European countries, aimed to assess PrEP knowledge and interest. "High objective risk" (HOR) was assessed using established risk criteria following EACS and CDC guidelines. Factors associated with interest in using PrEP were assessed in univariable and multivariable logistic regression models. Among 678 women, 12.5% (n = 85) were considered at HOR, 46.8% (n = 317) indicated prior PrEP knowledge and 18.0% (n = 122) reported interest in using PrEP. Among women at HOR, 40.0% (n = 34) were interested in PrEP. Factors significantly associated with PrEP interest in the final multivariable model were: younger age (18-29 years) (aOR 1.91[95CI: 1.07; 3.41]), bad self-perceived financial status (1.84[1.09; 3.11]), migrant status (south to north) (2.87[1.05; 7.89]), single or dating relationship status (1.93[1.23; 3.03]), sexual abuse history (1.86[1.17; 2.97]), "rather high"/ "high" self-perceived HIV risk (3.21[1.32; 7.81]), and HOR (2.49[1.42; 4.35]). These results show that women at HOR and those who perceived themselves to be at high risk are interested in using PrEP. There is a critical need for targeted information and improved access to PrEP to increase uptake of this HIV prevention tool to meet PrEP interest among women.
KW - ANTIRETROVIRAL PROPHYLAXIS
KW - FEMALE SEX WORKERS
KW - GENDER-BASED VIOLENCE
KW - HIV PREEXPOSURE PROPHYLAXIS
KW - INFECTION
KW - PERCEPTION
KW - PREVENTION
KW - RISK SCORING TOOL
KW - TRANSMISSION
KW - US WOMEN
KW - HIV PREVENTION
KW - MEN
KW - ORAL PREEXPOSURE PROPHYLAXIS
U2 - 10.1371/journal.pone.0246037
DO - 10.1371/journal.pone.0246037
M3 - Article
C2 - 33596225
VL - 16
SP - 1
EP - 15
JO - PLOS ONE
JF - PLOS ONE
SN - 1932-6203
IS - 2
M1 - 0246037
ER -