Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

Karen Heyninck, Linde Sabbe, Chandra Sekhar Chirumamilla, Katarzyna Szarc Vel Szic, Pieter Vander Veken, Kristien J. A. Lemmens, Maija Lahtela-Kakkonen, Stefan Naulaerts, Ken Op de Beeck, Kris Laukens, Guy Van Camp, Antje R. Weseler, Aalt Bast, Guido R. M. M. Haenen, Guy Haegeman, Wim Vanden Berghe

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
Original languageEnglish
Pages (from-to)48-61
JournalBiochemical Pharmacology
Volume109
DOIs
Publication statusPublished - 1 Jun 2016

Keywords

  • Antioxidant
  • Endothelial cell
  • Molecular pharmacology
  • Phytochemical
  • Signal transduction
  • Transcription regulation

Cite this

Heyninck, K., Sabbe, L., Chirumamilla, C. S., Szic, K. S. V., Veken, P. V., Lemmens, K. J. A., ... Berghe, W. V. (2016). Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway. Biochemical Pharmacology, 109, 48-61. https://doi.org/10.1016/j.bcp.2016.03.026
Heyninck, Karen ; Sabbe, Linde ; Chirumamilla, Chandra Sekhar ; Szic, Katarzyna Szarc Vel ; Veken, Pieter Vander ; Lemmens, Kristien J. A. ; Lahtela-Kakkonen, Maija ; Naulaerts, Stefan ; de Beeck, Ken Op ; Laukens, Kris ; Van Camp, Guy ; Weseler, Antje R. ; Bast, Aalt ; Haenen, Guido R. M. M. ; Haegeman, Guy ; Berghe, Wim Vanden. / Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway. In: Biochemical Pharmacology. 2016 ; Vol. 109. pp. 48-61.
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title = "Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway",
keywords = "Antioxidant, Endothelial cell, Molecular pharmacology, Phytochemical, Signal transduction, Transcription regulation",
author = "Karen Heyninck and Linde Sabbe and Chirumamilla, {Chandra Sekhar} and Szic, {Katarzyna Szarc Vel} and Veken, {Pieter Vander} and Lemmens, {Kristien J. A.} and Maija Lahtela-Kakkonen and Stefan Naulaerts and {de Beeck}, {Ken Op} and Kris Laukens and {Van Camp}, Guy and Weseler, {Antje R.} and Aalt Bast and Haenen, {Guido R. M. M.} and Guy Haegeman and Berghe, {Wim Vanden}",
year = "2016",
month = "6",
day = "1",
doi = "10.1016/j.bcp.2016.03.026",
language = "English",
volume = "109",
pages = "48--61",
journal = "Biochemical Pharmacology",
issn = "0006-2952",
publisher = "Elsevier Science",

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Heyninck, K, Sabbe, L, Chirumamilla, CS, Szic, KSV, Veken, PV, Lemmens, KJA, Lahtela-Kakkonen, M, Naulaerts, S, de Beeck, KO, Laukens, K, Van Camp, G, Weseler, AR, Bast, A, Haenen, GRMM, Haegeman, G & Berghe, WV 2016, 'Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway', Biochemical Pharmacology, vol. 109, pp. 48-61. https://doi.org/10.1016/j.bcp.2016.03.026

Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway. / Heyninck, Karen; Sabbe, Linde; Chirumamilla, Chandra Sekhar; Szic, Katarzyna Szarc Vel; Veken, Pieter Vander; Lemmens, Kristien J. A.; Lahtela-Kakkonen, Maija; Naulaerts, Stefan; de Beeck, Ken Op; Laukens, Kris; Van Camp, Guy; Weseler, Antje R.; Bast, Aalt; Haenen, Guido R. M. M.; Haegeman, Guy; Berghe, Wim Vanden.

In: Biochemical Pharmacology, Vol. 109, 01.06.2016, p. 48-61.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

AU - Heyninck, Karen

AU - Sabbe, Linde

AU - Chirumamilla, Chandra Sekhar

AU - Szic, Katarzyna Szarc Vel

AU - Veken, Pieter Vander

AU - Lemmens, Kristien J. A.

AU - Lahtela-Kakkonen, Maija

AU - Naulaerts, Stefan

AU - de Beeck, Ken Op

AU - Laukens, Kris

AU - Van Camp, Guy

AU - Weseler, Antje R.

AU - Bast, Aalt

AU - Haenen, Guido R. M. M.

AU - Haegeman, Guy

AU - Berghe, Wim Vanden

PY - 2016/6/1

Y1 - 2016/6/1

KW - Antioxidant

KW - Endothelial cell

KW - Molecular pharmacology

KW - Phytochemical

KW - Signal transduction

KW - Transcription regulation

U2 - 10.1016/j.bcp.2016.03.026

DO - 10.1016/j.bcp.2016.03.026

M3 - Article

VL - 109

SP - 48

EP - 61

JO - Biochemical Pharmacology

JF - Biochemical Pharmacology

SN - 0006-2952

ER -