Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

Karen Heyninck, Linde Sabbe, Chandra Sekhar Chirumamilla, Katarzyna Szarc Vel Szic, Pieter Vander Veken, Kristien J. A. Lemmens, Maija Lahtela-Kakkonen, Stefan Naulaerts, Ken Op de Beeck, Kris Laukens, Guy Van Camp, Antje R. Weseler, Aalt Bast, Guido R. M. M. Haenen, Guy Haegeman, Wim Vanden Berghe

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)48-61
JournalBiochemical Pharmacology
Volume109
DOIs
Publication statusPublished - 1 Jun 2016

Keywords

  • Antioxidant
  • Endothelial cell
  • Molecular pharmacology
  • Phytochemical
  • Signal transduction
  • Transcription regulation

Cite this

Heyninck, K., Sabbe, L., Chirumamilla, C. S., Szic, K. S. V., Veken, P. V., Lemmens, K. J. A., Lahtela-Kakkonen, M., Naulaerts, S., de Beeck, K. O., Laukens, K., Van Camp, G., Weseler, A. R., Bast, A., Haenen, G. R. M. M., Haegeman, G., & Berghe, W. V. (2016). Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway. Biochemical Pharmacology, 109, 48-61. https://doi.org/10.1016/j.bcp.2016.03.026