White Matter Hyperintensities Potentiate Hippocampal Volume Reduction in Non-Demented Older Individuals with Abnormal Amyloid-beta

Whitney M. Freeze*, Heidi I. L. Jacobs, Ed H. Gronenschild, Jacobus F. A. Jansen, Saartje Burgmans, Pauline Aalten, Lies Clerx, Stephanie J. Vos, Mark A. van Buchem, Frederik Barkhof, Wiesje M. van der Flier, Marcel M. Verbeek, Marcel Olde Rikkert, Walter H. Backes, Frans R. Verhey,

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)333-342
Number of pages10
JournalJournal of Alzheimer's Disease
Volume55
Issue number1
DOIs
Publication statusPublished - 1 Nov 2017

Keywords

  • Amyloid-beta
  • cerebral small vessel disease
  • dementia
  • neurodegeneration
  • MILD COGNITIVE IMPAIRMENT
  • SMALL-VESSEL DISEASE
  • CEREBROSPINAL-FLUID BIOMARKERS
  • SUBCORTICAL VASCULAR DEMENTIA
  • ALZHEIMERS-DISEASE
  • A-BETA
  • CEREBRAL MICROBLEEDS
  • NORMATIVE DATA
  • CEREBROVASCULAR-DISEASE
  • CORTICAL THICKNESS

Cite this

Freeze, Whitney M. ; Jacobs, Heidi I. L. ; Gronenschild, Ed H. ; Jansen, Jacobus F. A. ; Burgmans, Saartje ; Aalten, Pauline ; Clerx, Lies ; Vos, Stephanie J. ; van Buchem, Mark A. ; Barkhof, Frederik ; van der Flier, Wiesje M. ; Verbeek, Marcel M. ; Rikkert, Marcel Olde ; Backes, Walter H. ; Verhey, Frans R. / White Matter Hyperintensities Potentiate Hippocampal Volume Reduction in Non-Demented Older Individuals with Abnormal Amyloid-beta. In: Journal of Alzheimer's Disease. 2017 ; Vol. 55, No. 1. pp. 333-342.
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title = "White Matter Hyperintensities Potentiate Hippocampal Volume Reduction in Non-Demented Older Individuals with Abnormal Amyloid-beta",
keywords = "Amyloid-beta, cerebral small vessel disease, dementia, neurodegeneration, MILD COGNITIVE IMPAIRMENT, SMALL-VESSEL DISEASE, CEREBROSPINAL-FLUID BIOMARKERS, SUBCORTICAL VASCULAR DEMENTIA, ALZHEIMERS-DISEASE, A-BETA, CEREBRAL MICROBLEEDS, NORMATIVE DATA, CEREBROVASCULAR-DISEASE, CORTICAL THICKNESS",
author = "Freeze, {Whitney M.} and Jacobs, {Heidi I. L.} and Gronenschild, {Ed H.} and Jansen, {Jacobus F. A.} and Saartje Burgmans and Pauline Aalten and Lies Clerx and Vos, {Stephanie J.} and {van Buchem}, {Mark A.} and Frederik Barkhof and {van der Flier}, {Wiesje M.} and Verbeek, {Marcel M.} and Rikkert, {Marcel Olde} and Backes, {Walter H.} and Verhey, {Frans R.}",
year = "2017",
month = "11",
day = "1",
doi = "10.3233/JAD-160474",
language = "English",
volume = "55",
pages = "333--342",
journal = "Journal of Alzheimer's Disease",
issn = "1387-2877",
publisher = "IOS Press",
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}

White Matter Hyperintensities Potentiate Hippocampal Volume Reduction in Non-Demented Older Individuals with Abnormal Amyloid-beta. / Freeze, Whitney M.; Jacobs, Heidi I. L.; Gronenschild, Ed H.; Jansen, Jacobus F. A.; Burgmans, Saartje; Aalten, Pauline; Clerx, Lies; Vos, Stephanie J.; van Buchem, Mark A.; Barkhof, Frederik; van der Flier, Wiesje M.; Verbeek, Marcel M.; Rikkert, Marcel Olde; Backes, Walter H.; Verhey, Frans R.

In: Journal of Alzheimer's Disease, Vol. 55, No. 1, 01.11.2017, p. 333-342.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - White Matter Hyperintensities Potentiate Hippocampal Volume Reduction in Non-Demented Older Individuals with Abnormal Amyloid-beta

AU - Freeze, Whitney M.

AU - Jacobs, Heidi I. L.

AU - Gronenschild, Ed H.

AU - Jansen, Jacobus F. A.

AU - Burgmans, Saartje

AU - Aalten, Pauline

AU - Clerx, Lies

AU - Vos, Stephanie J.

AU - van Buchem, Mark A.

AU - Barkhof, Frederik

AU - van der Flier, Wiesje M.

AU - Verbeek, Marcel M.

AU - Rikkert, Marcel Olde

AU - Backes, Walter H.

AU - Verhey, Frans R.

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KW - dementia

KW - neurodegeneration

KW - MILD COGNITIVE IMPAIRMENT

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KW - CEREBROSPINAL-FLUID BIOMARKERS

KW - SUBCORTICAL VASCULAR DEMENTIA

KW - ALZHEIMERS-DISEASE

KW - A-BETA

KW - CEREBRAL MICROBLEEDS

KW - NORMATIVE DATA

KW - CEREBROVASCULAR-DISEASE

KW - CORTICAL THICKNESS

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EP - 342

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