Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects

Parastoo Fazelzadeh; Roland W. J. Hangelbroek; Peter J. Joris; Casper G. Schalkwijk; Diederik Esser; Lydia Afman; Thomas Hankemeier; Doris M. Jacobs; Velitchka V. Mihaleva; Sander Kersten; John Van Duynhoven; Mark V. Boekschoten

doi:10.1007/s11306-018-1328-x

Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects

Parastoo Fazelzadeh, Roland W. J. Hangelbroek, Peter J. Joris, Casper G. Schalkwijk, Diederik Esser, Lydia Afman, Thomas Hankemeier, Doris M. Jacobs, Velitchka V. Mihaleva, Sander Kersten, John Van Duynhoven^*, Mark V. Boekschoten

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

15 Citations (Web of Science)

Original language	English
Article number	46
Number of pages	13
Journal	Metabolomics
Volume	14
Issue number	4
DOIs	https://doi.org/10.1007/s11306-018-1328-x
Publication status	Published - Apr 2018

Keywords

Metabolic health
Mixed-meal challenge
Phenotype shift
INSULIN-RESISTANCE
GENE-EXPRESSION
PHENOTYPIC FLEXIBILITY
FATTY-ACIDS
HEALTH
INFLAMMATION
OVERWEIGHT
BIOMARKERS
SIGNATURE
PROFILES

Access to Document

10.1007/s11306-018-1328-x

Cite this

Fazelzadeh, P., Hangelbroek, R. W. J., Joris, P. J., Schalkwijk, C. G., Esser, D., Afman, L., Hankemeier, T., Jacobs, D. M., Mihaleva, V. V., Kersten, S., Van Duynhoven, J., & Boekschoten, M. V. (2018). Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects. Metabolomics, 14(4), [46]. https://doi.org/10.1007/s11306-018-1328-x

Fazelzadeh, Parastoo ; Hangelbroek, Roland W. J. ; Joris, Peter J. ; Schalkwijk, Casper G. ; Esser, Diederik ; Afman, Lydia ; Hankemeier, Thomas ; Jacobs, Doris M. ; Mihaleva, Velitchka V. ; Kersten, Sander ; Van Duynhoven, John ; Boekschoten, Mark V. / Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects. In: Metabolomics. 2018 ; Vol. 14, No. 4.

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title = "Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects",

keywords = "Metabolic health, Mixed-meal challenge, Phenotype shift, INSULIN-RESISTANCE, GENE-EXPRESSION, PHENOTYPIC FLEXIBILITY, FATTY-ACIDS, HEALTH, INFLAMMATION, OVERWEIGHT, BIOMARKERS, SIGNATURE, PROFILES",

author = "Parastoo Fazelzadeh and Hangelbroek, {Roland W. J.} and Joris, {Peter J.} and Schalkwijk, {Casper G.} and Diederik Esser and Lydia Afman and Thomas Hankemeier and Jacobs, {Doris M.} and Mihaleva, {Velitchka V.} and Sander Kersten and {Van Duynhoven}, John and Boekschoten, {Mark V.}",

year = "2018",

month = apr,

doi = "10.1007/s11306-018-1328-x",

language = "English",

volume = "14",

journal = "Metabolomics",

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publisher = "Springer, Cham",

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Fazelzadeh, P, Hangelbroek, RWJ, Joris, PJ , Schalkwijk, CG, Esser, D, Afman, L, Hankemeier, T, Jacobs, DM, Mihaleva, VV, Kersten, S, Van Duynhoven, J & Boekschoten, MV 2018, 'Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects', Metabolomics, vol. 14, no. 4, 46. https://doi.org/10.1007/s11306-018-1328-x

Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects. / Fazelzadeh, Parastoo; Hangelbroek, Roland W. J.; Joris, Peter J.; Schalkwijk, Casper G.; Esser, Diederik; Afman, Lydia; Hankemeier, Thomas; Jacobs, Doris M.; Mihaleva, Velitchka V.; Kersten, Sander; Van Duynhoven, John; Boekschoten, Mark V.

In: Metabolomics, Vol. 14, No. 4, 46, 04.2018.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects

AU - Fazelzadeh, Parastoo

AU - Hangelbroek, Roland W. J.

AU - Joris, Peter J.

AU - Schalkwijk, Casper G.

AU - Esser, Diederik

AU - Afman, Lydia

AU - Hankemeier, Thomas

AU - Jacobs, Doris M.

AU - Mihaleva, Velitchka V.

AU - Kersten, Sander

AU - Van Duynhoven, John

AU - Boekschoten, Mark V.

PY - 2018/4

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KW - Metabolic health

KW - Mixed-meal challenge

KW - Phenotype shift

KW - INSULIN-RESISTANCE

KW - GENE-EXPRESSION

KW - PHENOTYPIC FLEXIBILITY

KW - FATTY-ACIDS

KW - HEALTH

KW - INFLAMMATION

KW - OVERWEIGHT

KW - BIOMARKERS

KW - SIGNATURE

KW - PROFILES

U2 - 10.1007/s11306-018-1328-x

DO - 10.1007/s11306-018-1328-x

M3 - Article

C2 - 29527144

VL - 14

JO - Metabolomics

JF - Metabolomics

SN - 1573-3882

IS - 4

M1 - 46

ER -