Wearable Finger Pulse Oximetry for Continuous Oxygen Saturation Measurements During Daily Home Routines of Patients With Chronic Obstructive Pulmonary Disease (COPD) Over One Week: Observational Study

Joren Buekers, Jan Theunis, Patrick De Boever, Anouk W. Vaes, Maud Koopman, Eefje V. M. Janssen, Ernie F. M. Wouters, Martijn A. Spruit, Jean-Marie Aerts*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Web of Science)


Background: Chronic obstructive pulmonary disease (COPD) patients can suffer from low blood oxygen concentrations. Peripheral blood oxygen saturation (SpO(2)), as assessed by pulse oximetry, is commonly measured during the day using a spot check, or continuously during one or two nights to estimate nocturnal desaturation. Sampling at this frequency may overlook natural fluctuations in SpO(2).

Objective: This study used wearable finger pulse oximeters to continuously measure SpO(2) during daily home routines of COPD patients and assess natural SpO(2) fluctuations.

Methods: A total of 20 COPD patients wore a WristOx(2) pulse oximeter for 1 week to collect continuous SpO(2) measurements. A SenseWear Armband simultaneously collected actigraphy measurements to provide contextual information. SpO(2) time series were preprocessed and data quality was assessed afterward. Mean SpO(2) , SpO(2) SD, and cumulative time spent with SpO(2) below 90% (CT90) were calculated for every (1) day, (2) day in rest, and (3) night to assess SpO(2) fluctuations.

Results: A high percentage of valid SpO(2) data (daytime: 93.27%; nocturnal: 99.31%) could be obtained during a 7-day monitoring period, except during moderate-to-vigorous physical activity (MVPA) (67.86%). Mean nocturnal SpO(2) (89.9%, SD 3.4) was lower than mean daytime SpO(2 )in rest (92.1%, SD 2.9; P

Conclusions: Continuous SpO(2) measurements with wearable finger pulse oximeters identified significant SpO(2 )fluctuations between and within multiple days and nights of patients with COPD. Continuous SpO(2 ) measurements during daily home routines of patients with COPD generally had high amounts of valid data, except for motion artifacts during MVPA. The identified fluctuations can have implications for telemonitoring applications that are based on daily SpO(2) spot checks. CT90 values can vary greatly from night to night in patients with a nocturnal mean SpO(2) around 90%, indicating that these patients cannot be consistently categorized as desaturators or nondesaturators. We recommend using wearable sensors for continuous SpO(2 )measurements over longer time periods to determine the clinical relevance of the identified SpO(2 )fluctuations.

Original languageEnglish
Article number12866
Number of pages14
JournalJMIR mHealth and uHealth
Issue number6
Publication statusPublished - 11 Jun 2019


  • COPD
  • oxygen saturation
  • finger pulse oximeter
  • wearable sensor
  • nocturnal desaturation
  • telemonitoring

Cite this