Vitamin D status and parathyroid hormone in a urban population in Vietnam

L. T. Ho-Pham*, Nguyen D. Nguyen, T. Q. Lai, J. A. Eisman, T. V. Nguyen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Web of Science)

Abstract

In this cross-sectional study in Vietnam, the prevalence of vitamin D insufficiency was 46% in adult women and 20% in adult men. There was a linear inverse relationship between serum 25(OH)D and PTH concentrations, but there was no threshold of 25(OH)D at which PTH levels plateaued.Vitamin D insufficiency is adversely associated with health outcomes. Vitamin D status in Asian populations is not well documented. This study sought to assess vitamin D status and its relationship to parathyroid hormone in a Vietnamese population.This cross-sectional study involved 205 men and 432 women aged 18-87?years, who were randomly sampled from various districts in Ho Chi Minh City (Vietnam) according to a proportional sampling scheme. Serum concentration of 25(OH)D and PTH were measured by the Electrochemiluminescence immunoassay on the Roche Elecsys 10100/201 system (Roche Diagnosis Elecsys). Vitamin D insufficiency was quantified as serum 25(OH)D levels below 30?ng/ml (75?nmol/L).The average age for men and women was 43.8?18.4?years (mean?SD) and 47.7?17.1?years, respectively. The mean 25(OH)D concentration in men (36.8?10.2?ng/mL) was significantly higher than in women (30.1?5.9; P?
Original languageEnglish
Pages (from-to)241-248
JournalOsteoporosis International
Volume22
Issue number1
DOIs
Publication statusPublished - Jan 2011

Keywords

  • Asian
  • Epidemiology
  • Parathyroid hormone
  • Prevalence
  • Vietnamese
  • Vitamin D

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