Abstract
Obesity, which prevalence is increasing worldwide, is often characterized by low blood vitamin D level, which may relate to obesity-associated health risks like reduced insulin sensitivity. This dissertation aims to investigate the association between vitamin D and insulin sensitivity in individuals with obesity and insulin resistance. The studies presented in this thesis suggest that low vitamin D concentrations were not associated with insulin resistance in obesity. Furthermore, this research found that vitamin D supplementation did not improve tissue-specific insulin sensitivity in individuals with or at risk of insulin resistance.
Original language | English |
---|---|
Awarding Institution |
|
Supervisors/Advisors |
|
Award date | 28 Aug 2020 |
Place of Publication | Maastricht |
Publisher | |
Print ISBNs | 9789464023794 |
DOIs | |
Publication status | Published - 2020 |
Keywords
- vitamin D
- obesity
- tissue-specific insulin sensitivity