Vitamin D in insulin sensitivity and obesity: Fact or fiction?

Adriyan Pramono

Research output: ThesisDoctoral ThesisInternal

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Abstract

Obesity, which prevalence is increasing worldwide, is often characterized by low blood vitamin D level, which may relate to obesity-associated health risks like reduced insulin sensitivity. This dissertation aims to investigate the association between vitamin D and insulin sensitivity in individuals with obesity and insulin resistance. The studies presented in this thesis suggest that low vitamin D concentrations were not associated with insulin resistance in obesity. Furthermore, this research found that vitamin D supplementation did not improve tissue-specific insulin sensitivity in individuals with or at risk of insulin resistance.
Original languageEnglish
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Blaak, Ellen, Supervisor
  • Jocken, Johan, Co-Supervisor
Award date28 Aug 2020
Place of PublicationMaastricht
Publisher
Print ISBNs9789464023794
DOIs
Publication statusPublished - 2020

Keywords

  • vitamin D
  • obesity
  • tissue-specific insulin sensitivity

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