Visualizing the Human Subcortex Using Ultra-high Field Magnetic Resonance Imaging

M. C. Keuken*, B. R. Isaacs, R. Trampel, W. van der Zwaag, B. U. Forstmann

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

18 Citations (Web of Science)

Abstract

With the recent increased availability of ultra-high field (UHF) magnetic resonance imaging (MRI), substantial progress has been made in visualizing the human brain, which can now be done in extraordinary detail. This review provides an extensive overview of the use of UHF MRI in visualizing the human subcortex for both healthy and patient populations. The high inter-subject variability in size and location of subcortical structures limits the usability of atlases in the midbrain. Fortunately, the combined results of this review indicate that a large number of subcortical areas can be visualized in individual space using UHF MRI. Current limitations and potential solutions of UHF MRI for visualizing the subcortex are also discussed.
Original languageEnglish
Pages (from-to)513-545
Number of pages33
JournalBrain Topography
Volume31
Issue number4
DOIs
Publication statusPublished - 1 Jul 2018

Keywords

  • Subcortex
  • Ultra-high field
  • Magnetic resonance imaging
  • Review
  • DEEP-BRAIN-STIMULATION
  • 7 T MRI
  • HIGH-RESOLUTION MRI
  • SUSCEPTIBILITY MAPPING QSM
  • HUMAN SUBTHALAMIC NUCLEUS
  • SEROTONIN TRANSPORTER AVAILABILITY
  • PROGRESSIVE SUPRANUCLEAR PALSY
  • PERCEPTUAL DECISION-MAKING
  • SMALL VESSEL DISEASE
  • IN-VIVO HISTOLOGY

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