Visual Acuity While Walking and Oscillopsia Severity in Healthy Subjects and Patients With Unilateral and Bilateral Vestibular Function Loss

Nils Guinand*, Mark Pijnenburg, Maurice Janssen, Herman Kingma

*Corresponding author for this work

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To assess visual acuity (VA) while the patient is walking and to evaluate oscillopsia severity in patients with bilateral vestibulopathy (BV) and in patients with unilateral vestibular loss (UVL).Prospective study with a group of patients with BV, a group of patients with UVL, and a control group of healthy subjects.Tertiary academic center.Thirty seven patients with BV(age range, 29-80 years), 11 patients with UVL (age range, 48-75 years), and 57 healthy subjects (age range 20-77 years).Computation of the difference between the VA measured in static conditions and in dynamic conditions while walking on a treadmill at 2, 4, and 6 km/h. Oscillopsia severity was assessed with a questionnaire that we developed.Differences in VA at 2, 4, and 6 km/h and oscillopsia severity score.As a group, patients with BV showed a significant increase of the VA differences compared with healthy subjects (P <.001) and patients with UVL (P <.001) for all 3 walking velocities. Normality thresholds were defined as healthy subjects' 95% CI. Sensitivity of the test was 97% for discriminating patients with BV. Moderate to extreme oscillopsia severity was found in 81% of patients with BV and in 9% of patients with UVL. Differences in VA did not correlate with oscillopsia severity scores in patients with BV (P > .05 for all comparisons).We designed a highly sensitive, simple, cost-effective protocol to assess dynamic VA under physiologic conditions and a questionnaire to determine oscillopsia severity. Both tools could be used for the evaluation of new treatments for BV and patients with UVL.
Original languageEnglish
Pages (from-to)301-306
JournalArchives of Otolaryngology-Head & Neck Surgery
Issue number3
Publication statusPublished - Mar 2012

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