"Virtual" (Computed) Fractional Flow Reserve Current Challenges and Limitations

Paul D. Morris*, Frans N. van de Vosse, Patricia V. Lawford, D. Rodney Hose, Julian P. Gunn

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

75 Citations (Web of Science)


Fractional flow reserve (FFR) is the "gold standard" for assessing the physiological significance of coronary artery disease during invasive coronary angiography. FFR-guided percutaneous coronary intervention improves patient outcomes and reduces stent insertion and cost; yet, due to several practical and operator related factors, it is used in
Original languageEnglish
Pages (from-to)1009-1017
JournalJacc-Cardiovascular Interventions
Issue number8
Publication statusPublished - Jul 2015


  • computational fluid dynamics
  • computational modeling
  • coronary angiography
  • fractional flow reserve
  • percutaneous coronary intervention
  • virtual fractional flow reserve

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