Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery

Florian Schlotter; Kurt Huber; Christian Hassager; Sigrun Halvorsen; Pascal Vranckx; Janine Poess; Konstantin Krychtiuk; Roberto Lorusso; Nikolaos Bonaros; Patrick A. Calvert; Matteo Montorfano; Holger Thiele

doi:10.1093/eurheartj/ehae363

Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery

Florian Schlotter, Kurt Huber, Christian Hassager, Sigrun Halvorsen, Pascal Vranckx, Janine Poess, Konstantin Krychtiuk, Roberto Lorusso, Nikolaos Bonaros, Patrick A. Calvert, Matteo Montorfano, Holger Thiele^*

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Ventricular septal defects are a rare complication after acute myocardial infarction with a mortality close to 100% if left untreated. However, even surgical or interventional closure is associated with a very high mortality and currently no randomized controlled trials are available addressing the optimal treatment strategy of this disease. This state-of-the-art review and clinical consensus statement will outline the diagnosis, hemodynamic consequences and treatment strategies of ventricular septal defects complicating acute myocardial infarction with a focus on current available evidence and a focus on major research questions to fill the gap in evidence.

Original language	English
Pages (from-to)	2478-2492
Number of pages	15
Journal	European Heart Journal
Volume	45
Issue number	28
Early online date	1 Jun 2024
DOIs	https://doi.org/10.1093/eurheartj/ehae363
Publication status	Published - 21 Jul 2024

Keywords

Myocardial infarction
Ventricular septal defect
Device closure
Mechanical circulatory support
MECHANICAL CIRCULATORY SUPPORT
CARDIOGENIC-SHOCK
RISK-FACTORS
TRANSCATHETER CLOSURE
SURGICAL-TREATMENT
SHORT-TERM
AMERICAN-COLLEGE
PATCH TECHNIQUE
TASK-FORCE
RUPTURE

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Schlotter, F., Huber, K., Hassager, C., Halvorsen, S., Vranckx, P., Poess, J., Krychtiuk, K., Lorusso, R., Bonaros, N., Calvert, P. A., Montorfano, M., & Thiele, H. (2024). Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery. European Heart Journal, 45(28), 2478-2492. https://doi.org/10.1093/eurheartj/ehae363

Schlotter, Florian ; Huber, Kurt ; Hassager, Christian et al. / Ventricular septal defect complicating acute myocardial infarction : diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery. In: European Heart Journal. 2024 ; Vol. 45, No. 28. pp. 2478-2492.

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title = "Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery",

abstract = "Ventricular septal defects are a rare complication after acute myocardial infarction with a mortality close to 100% if left untreated. However, even surgical or interventional closure is associated with a very high mortality and currently no randomized controlled trials are available addressing the optimal treatment strategy of this disease. This state-of-the-art review and clinical consensus statement will outline the diagnosis, hemodynamic consequences and treatment strategies of ventricular septal defects complicating acute myocardial infarction with a focus on current available evidence and a focus on major research questions to fill the gap in evidence.",

keywords = "Myocardial infarction, Ventricular septal defect, Device closure, Mechanical circulatory support, MECHANICAL CIRCULATORY SUPPORT, CARDIOGENIC-SHOCK, RISK-FACTORS, TRANSCATHETER CLOSURE, SURGICAL-TREATMENT, SHORT-TERM, AMERICAN-COLLEGE, PATCH TECHNIQUE, TASK-FORCE, RUPTURE",

author = "Florian Schlotter and Kurt Huber and Christian Hassager and Sigrun Halvorsen and Pascal Vranckx and Janine Poess and Konstantin Krychtiuk and Roberto Lorusso and Nikolaos Bonaros and Calvert, {Patrick A.} and Matteo Montorfano and Holger Thiele",

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doi = "10.1093/eurheartj/ehae363",

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Schlotter, F, Huber, K, Hassager, C, Halvorsen, S, Vranckx, P, Poess, J, Krychtiuk, K, Lorusso, R, Bonaros, N, Calvert, PA, Montorfano, M & Thiele, H 2024, 'Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery', European Heart Journal, vol. 45, no. 28, pp. 2478-2492. https://doi.org/10.1093/eurheartj/ehae363

Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery. / Schlotter, Florian; Huber, Kurt; Hassager, Christian et al.
In: European Heart Journal, Vol. 45, No. 28, 21.07.2024, p. 2478-2492.

Research output: Contribution to journal › (Systematic) Review article › peer-review

TY - JOUR

T1 - Ventricular septal defect complicating acute myocardial infarction

T2 - diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery

AU - Schlotter, Florian

AU - Huber, Kurt

AU - Hassager, Christian

AU - Halvorsen, Sigrun

AU - Vranckx, Pascal

AU - Poess, Janine

AU - Krychtiuk, Konstantin

AU - Lorusso, Roberto

AU - Bonaros, Nikolaos

AU - Calvert, Patrick A.

AU - Montorfano, Matteo

AU - Thiele, Holger

PY - 2024/7/21

Y1 - 2024/7/21

N2 - Ventricular septal defects are a rare complication after acute myocardial infarction with a mortality close to 100% if left untreated. However, even surgical or interventional closure is associated with a very high mortality and currently no randomized controlled trials are available addressing the optimal treatment strategy of this disease. This state-of-the-art review and clinical consensus statement will outline the diagnosis, hemodynamic consequences and treatment strategies of ventricular septal defects complicating acute myocardial infarction with a focus on current available evidence and a focus on major research questions to fill the gap in evidence.

AB - Ventricular septal defects are a rare complication after acute myocardial infarction with a mortality close to 100% if left untreated. However, even surgical or interventional closure is associated with a very high mortality and currently no randomized controlled trials are available addressing the optimal treatment strategy of this disease. This state-of-the-art review and clinical consensus statement will outline the diagnosis, hemodynamic consequences and treatment strategies of ventricular septal defects complicating acute myocardial infarction with a focus on current available evidence and a focus on major research questions to fill the gap in evidence.

KW - Myocardial infarction

KW - Ventricular septal defect

KW - Device closure

KW - Mechanical circulatory support

KW - MECHANICAL CIRCULATORY SUPPORT

KW - CARDIOGENIC-SHOCK

KW - RISK-FACTORS

KW - TRANSCATHETER CLOSURE

KW - SURGICAL-TREATMENT

KW - SHORT-TERM

KW - AMERICAN-COLLEGE

KW - PATCH TECHNIQUE

KW - TASK-FORCE

KW - RUPTURE

U2 - 10.1093/eurheartj/ehae363

DO - 10.1093/eurheartj/ehae363

M3 - (Systematic) Review article

SN - 0195-668X

VL - 45

SP - 2478

EP - 2492

JO - European Heart Journal

JF - European Heart Journal

IS - 28

ER -

Schlotter F, Huber K, Hassager C, Halvorsen S, Vranckx P, Poess J et al. Ventricular septal defect complicating acute myocardial infarction: diagnosis and management. A Clinical Consensus Statement of the Association for Acute CardioVascular Care (ACVC) of the ESC, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the ESC Working Group on Cardiovascular Surgery. European Heart Journal. 2024 Jul 21;45(28):2478-2492. Epub 2024 Jun 1. doi: 10.1093/eurheartj/ehae363