Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects

Yingjie Zhao; Tingwei Guo; Ania Fiksinski; Elemi Breetvelt; Donna M. McDonald-McGinn; Terrence B. Crowley; Alexander Diacou; Maude Schneider; Stephan Eliez; Ann Swillen; Jeroen Breckpot; Joris Vermeesch; Eva W. C. Chow; Doron Gothelf; Sasja Duijff; Rens Evers; Therese A. van Amelsvoort; Marianne van den Bree; Michael Owen; Maria Niarchou; Carrie E. Bearden; Claudia Ornstein; Maria Pontillo; Antonino Buzzanca; Stefano Vicari; Marco Armando; Kieran C. Murphy; Clodagh Murphy; Sixto Garcia-Minaur; Nicole Philip; Linda Campbell; Jaume Morey-Canellas; Jasna Raventos; Jordi Rosell; Damian Heine-Suner; Robert J. Shprintzen; Raquel E. Gur; Elaine Zackai; Beverly S. Emanuel; Tao Wang; Wendy R. Kates; Anne S. Bassett; Jacob A. S. Vorstman; Bernice E. Morrow; Int Brain Behavior Consortium

doi:10.1002/ajmg.a.40359

Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects

Yingjie Zhao, Tingwei Guo, Ania Fiksinski, Elemi Breetvelt, Donna M. McDonald-McGinn, Terrence B. Crowley, Alexander Diacou, Maude Schneider, Stephan Eliez, Ann Swillen, Jeroen Breckpot, Joris Vermeesch, Eva W. C. Chow, Doron Gothelf, Sasja Duijff, Rens Evers, Therese A. van Amelsvoort, Marianne van den Bree, Michael Owen, Maria NiarchouCarrie E. Bearden, Claudia Ornstein, Maria Pontillo, Antonino Buzzanca, Stefano Vicari, Marco Armando, Kieran C. Murphy, Clodagh Murphy, Sixto Garcia-Minaur, Nicole Philip, Linda Campbell, Jaume Morey-Canellas, Jasna Raventos, Jordi Rosell, Damian Heine-Suner, Robert J. Shprintzen, Raquel E. Gur, Elaine Zackai, Beverly S. Emanuel, Tao Wang, Wendy R. Kates, Anne S. Bassett, Jacob A. S. Vorstman, Bernice E. Morrow^*, Int Brain Behavior Consortium

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	2172-2181
Number of pages	10
Journal	American Journal of Medical Genetics Part A
Volume	176
Issue number	10
DOIs	https://doi.org/10.1002/ajmg.a.40359
Publication status	Published - 1 Oct 2018

Keywords

22q11.2 deletion syndrome
deletion size
intellectual disability
IQ
low copy repeat
segmental duplication
CARDIO-FACIAL-SYNDROME
CONGENITAL HEART-DISEASE
SCHOOL-AGED CHILDREN
VELOCARDIOFACIAL SYNDROME
NEURODEVELOPMENTAL OUTCOMES
DEVELOPMENTAL TRAJECTORIES
COGNITIVE DECLINE
FOLLOW-UP
BRAIN
INTELLIGENCE

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10.1002/ajmg.a.40359

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Zhao, Y., Guo, T., Fiksinski, A., Breetvelt, E., McDonald-McGinn, D. M., Crowley, T. B., Diacou, A., Schneider, M., Eliez, S., Swillen, A., Breckpot, J., Vermeesch, J., Chow, E. W. C., Gothelf, D., Duijff, S., Evers, R., van Amelsvoort, T. A., van den Bree, M., Owen, M., ... Int Brain Behavior Consortium (2018). Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects. American Journal of Medical Genetics Part A, 176(10), 2172-2181. https://doi.org/10.1002/ajmg.a.40359

Zhao, Yingjie ; Guo, Tingwei ; Fiksinski, Ania ; Breetvelt, Elemi ; McDonald-McGinn, Donna M. ; Crowley, Terrence B. ; Diacou, Alexander ; Schneider, Maude ; Eliez, Stephan ; Swillen, Ann ; Breckpot, Jeroen ; Vermeesch, Joris ; Chow, Eva W. C. ; Gothelf, Doron ; Duijff, Sasja ; Evers, Rens ; van Amelsvoort, Therese A. ; van den Bree, Marianne ; Owen, Michael ; Niarchou, Maria ; Bearden, Carrie E. ; Ornstein, Claudia ; Pontillo, Maria ; Buzzanca, Antonino ; Vicari, Stefano ; Armando, Marco ; Murphy, Kieran C. ; Murphy, Clodagh ; Garcia-Minaur, Sixto ; Philip, Nicole ; Campbell, Linda ; Morey-Canellas, Jaume ; Raventos, Jasna ; Rosell, Jordi ; Heine-Suner, Damian ; Shprintzen, Robert J. ; Gur, Raquel E. ; Zackai, Elaine ; Emanuel, Beverly S. ; Wang, Tao ; Kates, Wendy R. ; Bassett, Anne S. ; Vorstman, Jacob A. S. ; Morrow, Bernice E. ; Int Brain Behavior Consortium. / Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects. In: American Journal of Medical Genetics Part A. 2018 ; Vol. 176, No. 10. pp. 2172-2181.

@article{c60bb0c4dc0d4a8abf954728644baf82,

title = "Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects",

keywords = "22q11.2 deletion syndrome, deletion size, intellectual disability, IQ, low copy repeat, segmental duplication, CARDIO-FACIAL-SYNDROME, CONGENITAL HEART-DISEASE, SCHOOL-AGED CHILDREN, VELOCARDIOFACIAL SYNDROME, NEURODEVELOPMENTAL OUTCOMES, DEVELOPMENTAL TRAJECTORIES, COGNITIVE DECLINE, FOLLOW-UP, BRAIN, INTELLIGENCE",

author = "Yingjie Zhao and Tingwei Guo and Ania Fiksinski and Elemi Breetvelt and McDonald-McGinn, {Donna M.} and Crowley, {Terrence B.} and Alexander Diacou and Maude Schneider and Stephan Eliez and Ann Swillen and Jeroen Breckpot and Joris Vermeesch and Chow, {Eva W. C.} and Doron Gothelf and Sasja Duijff and Rens Evers and {van Amelsvoort}, {Therese A.} and {van den Bree}, Marianne and Michael Owen and Maria Niarchou and Bearden, {Carrie E.} and Claudia Ornstein and Maria Pontillo and Antonino Buzzanca and Stefano Vicari and Marco Armando and Murphy, {Kieran C.} and Clodagh Murphy and Sixto Garcia-Minaur and Nicole Philip and Linda Campbell and Jaume Morey-Canellas and Jasna Raventos and Jordi Rosell and Damian Heine-Suner and Shprintzen, {Robert J.} and Gur, {Raquel E.} and Elaine Zackai and Emanuel, {Beverly S.} and Tao Wang and Kates, {Wendy R.} and Bassett, {Anne S.} and Vorstman, {Jacob A. S.} and Morrow, {Bernice E.} and {Int Brain Behavior Consortium}",

year = "2018",

month = oct,

day = "1",

doi = "10.1002/ajmg.a.40359",

language = "English",

volume = "176",

pages = "2172--2181",

journal = "American Journal of Medical Genetics Part A",

issn = "1552-4825",

publisher = "Wiley",

number = "10",

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Zhao, Y, Guo, T, Fiksinski, A, Breetvelt, E, McDonald-McGinn, DM, Crowley, TB, Diacou, A, Schneider, M, Eliez, S, Swillen, A, Breckpot, J, Vermeesch, J, Chow, EWC, Gothelf, D, Duijff, S, Evers, R, van Amelsvoort, TA, van den Bree, M, Owen, M, Niarchou, M, Bearden, CE, Ornstein, C, Pontillo, M, Buzzanca, A, Vicari, S, Armando, M, Murphy, KC, Murphy, C, Garcia-Minaur, S, Philip, N, Campbell, L, Morey-Canellas, J, Raventos, J, Rosell, J, Heine-Suner, D, Shprintzen, RJ, Gur, RE, Zackai, E, Emanuel, BS, Wang, T, Kates, WR, Bassett, AS, Vorstman, JAS, Morrow, BE & Int Brain Behavior Consortium 2018, 'Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects', American Journal of Medical Genetics Part A, vol. 176, no. 10, pp. 2172-2181. https://doi.org/10.1002/ajmg.a.40359

Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects. / Zhao, Yingjie; Guo, Tingwei; Fiksinski, Ania; Breetvelt, Elemi; McDonald-McGinn, Donna M.; Crowley, Terrence B.; Diacou, Alexander; Schneider, Maude; Eliez, Stephan; Swillen, Ann; Breckpot, Jeroen; Vermeesch, Joris; Chow, Eva W. C.; Gothelf, Doron; Duijff, Sasja; Evers, Rens; van Amelsvoort, Therese A.; van den Bree, Marianne; Owen, Michael; Niarchou, Maria; Bearden, Carrie E.; Ornstein, Claudia; Pontillo, Maria; Buzzanca, Antonino; Vicari, Stefano; Armando, Marco; Murphy, Kieran C.; Murphy, Clodagh; Garcia-Minaur, Sixto; Philip, Nicole; Campbell, Linda; Morey-Canellas, Jaume; Raventos, Jasna; Rosell, Jordi; Heine-Suner, Damian; Shprintzen, Robert J.; Gur, Raquel E.; Zackai, Elaine; Emanuel, Beverly S.; Wang, Tao; Kates, Wendy R.; Bassett, Anne S.; Vorstman, Jacob A. S.; Morrow, Bernice E.; Int Brain Behavior Consortium.

In: American Journal of Medical Genetics Part A, Vol. 176, No. 10, 01.10.2018, p. 2172-2181.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects

AU - Zhao, Yingjie

AU - Guo, Tingwei

AU - Fiksinski, Ania

AU - Breetvelt, Elemi

AU - McDonald-McGinn, Donna M.

AU - Crowley, Terrence B.

AU - Diacou, Alexander

AU - Schneider, Maude

AU - Eliez, Stephan

AU - Swillen, Ann

AU - Breckpot, Jeroen

AU - Vermeesch, Joris

AU - Chow, Eva W. C.

AU - Gothelf, Doron

AU - Duijff, Sasja

AU - Evers, Rens

AU - van Amelsvoort, Therese A.

AU - van den Bree, Marianne

AU - Owen, Michael

AU - Niarchou, Maria

AU - Bearden, Carrie E.

AU - Ornstein, Claudia

AU - Pontillo, Maria

AU - Buzzanca, Antonino

AU - Vicari, Stefano

AU - Armando, Marco

AU - Murphy, Kieran C.

AU - Murphy, Clodagh

AU - Garcia-Minaur, Sixto

AU - Philip, Nicole

AU - Campbell, Linda

AU - Morey-Canellas, Jaume

AU - Raventos, Jasna

AU - Rosell, Jordi

AU - Heine-Suner, Damian

AU - Shprintzen, Robert J.

AU - Gur, Raquel E.

AU - Zackai, Elaine

AU - Emanuel, Beverly S.

AU - Wang, Tao

AU - Kates, Wendy R.

AU - Bassett, Anne S.

AU - Vorstman, Jacob A. S.

AU - Morrow, Bernice E.

AU - Int Brain Behavior Consortium

PY - 2018/10/1

Y1 - 2018/10/1

KW - 22q11.2 deletion syndrome

KW - deletion size

KW - intellectual disability

KW - IQ

KW - low copy repeat

KW - segmental duplication

KW - CARDIO-FACIAL-SYNDROME

KW - CONGENITAL HEART-DISEASE

KW - SCHOOL-AGED CHILDREN

KW - VELOCARDIOFACIAL SYNDROME

KW - NEURODEVELOPMENTAL OUTCOMES

KW - DEVELOPMENTAL TRAJECTORIES

KW - COGNITIVE DECLINE

KW - FOLLOW-UP

KW - BRAIN

KW - INTELLIGENCE

U2 - 10.1002/ajmg.a.40359

DO - 10.1002/ajmg.a.40359

M3 - Article

C2 - 30289625

VL - 176

SP - 2172

EP - 2181

JO - American Journal of Medical Genetics Part A

JF - American Journal of Medical Genetics Part A

SN - 1552-4825

IS - 10

ER -