Validity of an automatic measure protocol in distal femur for allograft selection from a three-dimensional virtual bone bank system

Lucas Eduardo Ritacco*, Christof Seiler, German Luis Farfalli, Lutz Nolte, Mauricio Reyes, Domingo Luis Muscolo, Luis Aponte Tinao

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Web of Science)


Osteoarticular allograft is one possible treatment in wide surgical resections with large defects. Performing best osteoarticular allograft selection is of great relevance for optimal exploitation of the bone databank, good surgery outcome and patient's recovery. Current approaches are, however, very time consuming hindering these points in practice. We present a validation study of a software able to perform automatic bone measurements used to automatically assess the distal femur sizes across a databank. 170 distal femur surfaces were reconstructed from CT data and measured manually using a size measure protocol taking into account the transepicondyler distance (A), anterior-posterior distance in medial condyle (B) and anterior-posterior distance in lateral condyle (C). Intra- and inter-observer studies were conducted and regarded as ground truth measurements. Manual and automatic measures were compared. For the automatic measurements, the correlation coefficients between observer one and automatic method, were of 0.99 for A measure and 0.96 for B and C measures. The average time needed to perform the measurements was of 16 h for both manual measurements, and of 3 min for the automatic method. Results demonstrate the high reliability and, most importantly, high repeatability of the proposed approach, and considerable speed-up on the planning.

Original languageEnglish
Pages (from-to)213-20
Number of pages8
JournalCell and Tissue Banking
Issue number2
Publication statusPublished - Jun 2013
Externally publishedYes


  • Adult
  • Aged
  • Aged, 80 and over
  • Allografts
  • Automation/methods
  • Bone Banks
  • Bone Transplantation/methods
  • Databases, Factual
  • Donor Selection/methods
  • Female
  • Femur/diagnostic imaging
  • Humans
  • Imaging, Three-Dimensional/methods
  • Male
  • Middle Aged
  • Observer Variation
  • Reproducibility of Results
  • Software
  • Tomography, X-Ray Computed
  • User-Computer Interface

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