Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T

Alexander Streng, Douwe de Boer, Freek Bouwman, Edwin Mariman, A. Scholten, Marja P. van Dieijen - Visser, Will Wodzig*

*Corresponding author for this work

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Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: "Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T" W. This article presents data describing aspects of the validation and optimisation of this assay. The data consists of several figures, an excel file containing the results of a sequence identity search, and a description of the raw mass spectrometry (MS) data files, deposited in the ProteomeXchange repository with id PRIDE: PXD003187. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (

Original languageEnglish
Pages (from-to)397-405
Number of pages9
JournalData in brief
Publication statusPublished - Jun 2016

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