Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

Sarah Westwood; Alison L. Baird; Sneha N. Anand; Alejo J. Nevado-Holgado; Andrey Kormilitzin; Liu Shi; Abdul Hye; Nicholas J. Ashton; Angharad R. Morgan; Isabelle Bos; Stephanie J. B. Vos; Susan Baker; Noel J. Buckley; Mara Ten Kate; Philip Scheltens; Charlotte E. Teunissen; Rik Vandenberghe; Silvy Gabel; Karen Meersmans; Sebastiaan Engelborghs; Ellen E. De Roeck; Kristel Sleegers; Giovanni B. Frisoni; Olivier Blin; Jill C. Richardson; Regis Bordet; Jose L. Molinuevo; Lorena Rami; Anders Wallin; Petronella Kettunen; Magda Tsolaki; Frans Verhey; Alberto Lleo; Isabel Sala; Julius Popp; Gwendoline Peyratout; Pablo Martinez-Lage; Mikel Tainta; Peter Johannsen; Yvonne Freund-Levi; Lutz Froelich; Valerija Dobricic; Cristina Legido-Quigley; Lars Bertram; Frederik Barkhof; Henrik Zetterberg; B. Paul Morgan; Johannes Streffer; Pieter Jelle Visser; Simon Lovestone

doi:10.3233/JAD-190434

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

Sarah Westwood, Alison L. Baird, Sneha N. Anand, Alejo J. Nevado-Holgado, Andrey Kormilitzin, Liu Shi, Abdul Hye, Nicholas J. Ashton, Angharad R. Morgan, Isabelle Bos, Stephanie J. B. Vos, Susan Baker, Noel J. Buckley, Mara Ten Kate, Philip Scheltens, Charlotte E. Teunissen, Rik Vandenberghe, Silvy Gabel, Karen Meersmans, Sebastiaan EngelborghsEllen E. De Roeck, Kristel Sleegers, Giovanni B. Frisoni, Olivier Blin, Jill C. Richardson, Regis Bordet, Jose L. Molinuevo, Lorena Rami, Anders Wallin, Petronella Kettunen, Magda Tsolaki, Frans Verhey, Alberto Lleo, Isabel Sala, Julius Popp, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Froelich, Valerija Dobricic, Cristina Legido-Quigley, Lars Bertram, Frederik Barkhof, Henrik Zetterberg, B. Paul Morgan, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	213-225
Number of pages	13
Journal	Journal of Alzheimer's Disease
Volume	74
Issue number	1
DOIs	https://doi.org/10.3233/JAD-190434
Publication status	Published - 2020

Keywords

Alzheimer's disease
amyloid-beta
biomarkers
plasma
proteomics
CEREBROSPINAL-FLUID BIOMARKERS
MILD COGNITIVE IMPAIRMENT
BLOOD-BASED BIOMARKER
DEMENTIA
PROGRESSION
EXPRESSION
GUIDELINES
PATHOLOGY
MARKERS
LECTIN

Access to Document

10.3233/JAD-190434

Cite this

Westwood, S., Baird, A. L., Anand, S. N., Nevado-Holgado, A. J., Kormilitzin, A., Shi, L., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., Vos, S. J. B., Baker, S., Buckley, N. J., Ten Kate, M., Scheltens, P., Teunissen, C. E., Vandenberghe, R., Gabel, S., Meersmans, K., ... Lovestone, S. (2020). Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort. Journal of Alzheimer's Disease, 74(1), 213-225. https://doi.org/10.3233/JAD-190434

Westwood, Sarah ; Baird, Alison L. ; Anand, Sneha N. ; Nevado-Holgado, Alejo J. ; Kormilitzin, Andrey ; Shi, Liu ; Hye, Abdul ; Ashton, Nicholas J. ; Morgan, Angharad R. ; Bos, Isabelle ; Vos, Stephanie J. B. ; Baker, Susan ; Buckley, Noel J. ; Ten Kate, Mara ; Scheltens, Philip ; Teunissen, Charlotte E. ; Vandenberghe, Rik ; Gabel, Silvy ; Meersmans, Karen ; Engelborghs, Sebastiaan ; De Roeck, Ellen E. ; Sleegers, Kristel ; Frisoni, Giovanni B. ; Blin, Olivier ; Richardson, Jill C. ; Bordet, Regis ; Molinuevo, Jose L. ; Rami, Lorena ; Wallin, Anders ; Kettunen, Petronella ; Tsolaki, Magda ; Verhey, Frans ; Lleo, Alberto ; Sala, Isabel ; Popp, Julius ; Peyratout, Gwendoline ; Martinez-Lage, Pablo ; Tainta, Mikel ; Johannsen, Peter ; Freund-Levi, Yvonne ; Froelich, Lutz ; Dobricic, Valerija ; Legido-Quigley, Cristina ; Bertram, Lars ; Barkhof, Frederik ; Zetterberg, Henrik ; Morgan, B. Paul ; Streffer, Johannes ; Visser, Pieter Jelle ; Lovestone, Simon. / Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort. In: Journal of Alzheimer's Disease. 2020 ; Vol. 74, No. 1. pp. 213-225.

@article{b0b6c270820b488eafc44d569aa3a1a5,

title = "Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort",

keywords = "Alzheimer's disease, amyloid-beta, biomarkers, plasma, proteomics, CEREBROSPINAL-FLUID BIOMARKERS, MILD COGNITIVE IMPAIRMENT, BLOOD-BASED BIOMARKER, DEMENTIA, PROGRESSION, EXPRESSION, GUIDELINES, PATHOLOGY, MARKERS, LECTIN",

author = "Sarah Westwood and Baird, {Alison L.} and Anand, {Sneha N.} and Nevado-Holgado, {Alejo J.} and Andrey Kormilitzin and Liu Shi and Abdul Hye and Ashton, {Nicholas J.} and Morgan, {Angharad R.} and Isabelle Bos and Vos, {Stephanie J. B.} and Susan Baker and Buckley, {Noel J.} and {Ten Kate}, Mara and Philip Scheltens and Teunissen, {Charlotte E.} and Rik Vandenberghe and Silvy Gabel and Karen Meersmans and Sebastiaan Engelborghs and {De Roeck}, {Ellen E.} and Kristel Sleegers and Frisoni, {Giovanni B.} and Olivier Blin and Richardson, {Jill C.} and Regis Bordet and Molinuevo, {Jose L.} and Lorena Rami and Anders Wallin and Petronella Kettunen and Magda Tsolaki and Frans Verhey and Alberto Lleo and Isabel Sala and Julius Popp and Gwendoline Peyratout and Pablo Martinez-Lage and Mikel Tainta and Peter Johannsen and Yvonne Freund-Levi and Lutz Froelich and Valerija Dobricic and Cristina Legido-Quigley and Lars Bertram and Frederik Barkhof and Henrik Zetterberg and Morgan, {B. Paul} and Johannes Streffer and Visser, {Pieter Jelle} and Simon Lovestone",

year = "2020",

doi = "10.3233/JAD-190434",

language = "English",

volume = "74",

pages = "213--225",

journal = "Journal of Alzheimer's Disease",

issn = "1387-2877",

publisher = "IOS Press",

number = "1",

}

Westwood, S, Baird, AL, Anand, SN, Nevado-Holgado, AJ, Kormilitzin, A, Shi, L, Hye, A, Ashton, NJ, Morgan, AR, Bos, I , Vos, SJB, Baker, S, Buckley, NJ, Ten Kate, M, Scheltens, P, Teunissen, CE, Vandenberghe, R, Gabel, S, Meersmans, K, Engelborghs, S, De Roeck, EE, Sleegers, K, Frisoni, GB, Blin, O, Richardson, JC, Bordet, R, Molinuevo, JL, Rami, L, Wallin, A, Kettunen, P, Tsolaki, M, Verhey, F, Lleo, A, Sala, I, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Johannsen, P, Freund-Levi, Y, Froelich, L, Dobricic, V, Legido-Quigley, C, Bertram, L, Barkhof, F, Zetterberg, H, Morgan, BP, Streffer, J, Visser, PJ & Lovestone, S 2020, 'Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort', Journal of Alzheimer's Disease, vol. 74, no. 1, pp. 213-225. https://doi.org/10.3233/JAD-190434

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort. / Westwood, Sarah; Baird, Alison L.; Anand, Sneha N.; Nevado-Holgado, Alejo J.; Kormilitzin, Andrey; Shi, Liu; Hye, Abdul; Ashton, Nicholas J.; Morgan, Angharad R.; Bos, Isabelle ; Vos, Stephanie J. B.; Baker, Susan; Buckley, Noel J.; Ten Kate, Mara; Scheltens, Philip; Teunissen, Charlotte E.; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E.; Sleegers, Kristel; Frisoni, Giovanni B.; Blin, Olivier; Richardson, Jill C.; Bordet, Regis; Molinuevo, Jose L.; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lleo, Alberto; Sala, Isabel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Freund-Levi, Yvonne; Froelich, Lutz; Dobricic, Valerija; Legido-Quigley, Cristina; Bertram, Lars; Barkhof, Frederik; Zetterberg, Henrik; Morgan, B. Paul; Streffer, Johannes; Visser, Pieter Jelle; Lovestone, Simon.

In: Journal of Alzheimer's Disease, Vol. 74, No. 1, 2020, p. 213-225.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

AU - Westwood, Sarah

AU - Baird, Alison L.

AU - Anand, Sneha N.

AU - Nevado-Holgado, Alejo J.

AU - Kormilitzin, Andrey

AU - Shi, Liu

AU - Hye, Abdul

AU - Ashton, Nicholas J.

AU - Morgan, Angharad R.

AU - Bos, Isabelle

AU - Vos, Stephanie J. B.

AU - Baker, Susan

AU - Buckley, Noel J.

AU - Ten Kate, Mara

AU - Scheltens, Philip

AU - Teunissen, Charlotte E.

AU - Vandenberghe, Rik

AU - Gabel, Silvy

AU - Meersmans, Karen

AU - Engelborghs, Sebastiaan

AU - De Roeck, Ellen E.

AU - Sleegers, Kristel

AU - Frisoni, Giovanni B.

AU - Blin, Olivier

AU - Richardson, Jill C.

AU - Bordet, Regis

AU - Molinuevo, Jose L.

AU - Rami, Lorena

AU - Wallin, Anders

AU - Kettunen, Petronella

AU - Tsolaki, Magda

AU - Verhey, Frans

AU - Lleo, Alberto

AU - Sala, Isabel

AU - Popp, Julius

AU - Peyratout, Gwendoline

AU - Martinez-Lage, Pablo

AU - Tainta, Mikel

AU - Johannsen, Peter

AU - Freund-Levi, Yvonne

AU - Froelich, Lutz

AU - Dobricic, Valerija

AU - Legido-Quigley, Cristina

AU - Bertram, Lars

AU - Barkhof, Frederik

AU - Zetterberg, Henrik

AU - Morgan, B. Paul

AU - Streffer, Johannes

AU - Visser, Pieter Jelle

AU - Lovestone, Simon

PY - 2020

Y1 - 2020

KW - Alzheimer's disease

KW - amyloid-beta

KW - biomarkers

KW - plasma

KW - proteomics

KW - CEREBROSPINAL-FLUID BIOMARKERS

KW - MILD COGNITIVE IMPAIRMENT

KW - BLOOD-BASED BIOMARKER

KW - DEMENTIA

KW - PROGRESSION

KW - EXPRESSION

KW - GUIDELINES

KW - PATHOLOGY

KW - MARKERS

KW - LECTIN

U2 - 10.3233/JAD-190434

DO - 10.3233/JAD-190434

M3 - Article

VL - 74

SP - 213

EP - 225

JO - Journal of Alzheimer's Disease

JF - Journal of Alzheimer's Disease

SN - 1387-2877

IS - 1

ER -