Using machine learning to predict mental healthcare consumption in non -affective psychosis

Sascha Kwakernaak*, Kasper van Mens, Wiepke Cahn, Richard Janssen, Behrooz Z. Alizadeh, Therese van Amelsvoor, Agna A. Bartels-Velthuis, Lieuwe de Haan, Jurjen J. Luyk, Frederike Schirmbeck, Claudia J. P. Simons, Jim van Os, GRP Investigators

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The main goal of the study was to predict individual patients' future mental healthcare consumption, and thereby enhancing the design of an efficient demand-oriented mental healthcare system by focusing on a patient population associated with intensive mental healthcare consumption. Factors that affect the mental healthcare consumption of service users with non-affective psychosis were identified, and subsequently used in a prognostic model to predict future healthcare consumption.This study was a secondary analysis of an existing dataset from the GROUP study. Based on mental healthcare consumption, patients with non-affective psychosis were divided into two groups: low (N = 579) and high (N = 488) intensive mental healthcare consumers. Three different techniques from the field of machine learning were applied on crosssectional data to identify risk factors: logistic regression, classification tree and a random forest. Subsequently, the same techniques were applied longitudinally in order to predict future healthcare consumption.Identified variables that affected healthcare consumption were the number of psychotic episodes, paid employment, engagement in social activities, previous healthcare consumption, and met needs. Analyses showed that the random forest method is best suited to model risk factors, and that these relations predict future healthcare consumption (AUC 0.71, PPV 0.65).Machine learning techniques provide valuable information for identifying risk factors in psychosis. They may thus help clinicians optimize allocation of mental healthcare resources by predicting future healthcare consumption.Copyright © 2020 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)166-172
Number of pages7
JournalSchizophrenia Research
Volume218
DOIs
Publication statusPublished - Apr 2020

Keywords

  • COGNITIVE-BEHAVIORAL THERAPY
  • SUBSTANCE USE
  • FOLLOW-UP
  • HIGH-RISK
  • ANTIPSYCHOTIC MEDICATION
  • FAMILY INTERVENTION
  • UNTREATED PSYCHOSIS
  • SERVICE USE
  • SCHIZOPHRENIA
  • HOSPITALIZATION

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