TY - JOUR
T1 - Using machine learning to predict mental healthcare consumption in non -affective psychosis
AU - Kwakernaak, Sascha
AU - van Mens, Kasper
AU - Cahn, Wiepke
AU - Janssen, Richard
AU - Alizadeh, Behrooz Z.
AU - van Amelsvoor, Therese
AU - Bartels-Velthuis, Agna A.
AU - de Haan, Lieuwe
AU - Luyk, Jurjen J.
AU - Schirmbeck, Frederike
AU - Simons, Claudia J. P.
AU - van Os, Jim
AU - GRP Investigators
N1 - Funding Information:
The infrastructure for the GROUP study is funded through the Geestkracht programme of the Dutch Health Research Council (Zon-Mw, grant number 10-000-1001), and matching funds from participating pharmaceutical companies (Lundbeck, AstraZeneca, Eli Lilly, Janssen Cilag) and universities and mental healthcare organizations (Amsterdam: Academic Psychiatric Centre of the Academic Medical Center and the mental health institutions): GGZ Ingeest, Arkin, Dijk en Duin, GGZ Rivierduinen, Erasmus Medical Centre, GGZ Noord Holland Noord. Groningen: University Medical Center Groningen and the mental health institutions: Lentis, GGZ Friesland, GGZ Drenthe, Dimence, Mediant, GGNet Warnsveld, Yulius Dordrecht and Parnassia psycho-medical center The Hague. Maastricht: Maastricht University Medical Centre and the mental health institutions: GGZ Eindhoven en De Kempen, GGZ Breburg, GGZ Oost-Brabant, Vincent van Gogh voor Geestelijke Gezondheid, Mondriaan, Virenze riagg, Zuyderland GGZ, MET ggz, Universitair Centrum Sint-Jozef Kortenberg, CAPRI University of Antwerp, PC Ziekeren Sint-Truiden, PZ Sancta Maria Sint-Truiden, GGZ Overpelt, OPZ Rekem. Utrecht: University Medical Center Utrecht and the mental health institutions Altrecht, GGZ Centraal and Delta.
Funding Information:
The infrastructure for the GROUP study is funded through the Geestkracht programme of the Dutch Health Research Council (Zon-Mw, grant number 10-000-1001 ), and matching funds from participating pharmaceutical companies ( Lundbeck , AstraZeneca , Eli Lilly , Janssen Cilag ) and universities and mental healthcare organizations (Amsterdam: Academic Psychiatric Centre of the Academic Medical Center and the mental health institutions): GGZ Ingeest , Arkin , Dijk en Duin , GGZ Rivierduinen , Erasmus Medical Centre , GGZ Noord Holland Noord . Groningen: University Medical Center Groningen and the mental health institutions: Lentis , GGZ Friesland , GGZ Drenthe , Dimence , Mediant , GGNet Warnsveld , Yulius Dordrecht and Parnassia psycho-medical center The Hague. Maastricht: Maastricht University Medical Centre and the mental health institutions: GGZ Eindhoven en De Kempen , GGZ Breburg , GGZ Oost-Brabant , Vincent van Gogh voor Geestelijke Gezondheid , Mondriaan , Virenze riagg , Zuyderland GGZ , MET ggz , Universitair Centrum Sint-Jozef Kortenberg , CAPRI University of Antwerp , PC Ziekeren Sint-Truiden , PZ Sancta Maria Sint-Truiden , GGZ Overpelt , OPZ Rekem . Utrecht: University Medical Center Utrecht and the mental health institutions Altrecht , GGZ Centraal and Delta .
Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2020/4
Y1 - 2020/4
N2 - The main goal of the study was to predict individual patients' future mental healthcare consumption, and thereby enhancing the design of an efficient demand-oriented mental healthcare system by focusing on a patient population associated with intensive mental healthcare consumption. Factors that affect the mental healthcare consumption of service users with non-affective psychosis were identified, and subsequently used in a prognostic model to predict future healthcare consumption.This study was a secondary analysis of an existing dataset from the GROUP study. Based on mental healthcare consumption, patients with non-affective psychosis were divided into two groups: low (N = 579) and high (N = 488) intensive mental healthcare consumers. Three different techniques from the field of machine learning were applied on crosssectional data to identify risk factors: logistic regression, classification tree and a random forest. Subsequently, the same techniques were applied longitudinally in order to predict future healthcare consumption.Identified variables that affected healthcare consumption were the number of psychotic episodes, paid employment, engagement in social activities, previous healthcare consumption, and met needs. Analyses showed that the random forest method is best suited to model risk factors, and that these relations predict future healthcare consumption (AUC 0.71, PPV 0.65).Machine learning techniques provide valuable information for identifying risk factors in psychosis. They may thus help clinicians optimize allocation of mental healthcare resources by predicting future healthcare consumption.Copyright © 2020 Elsevier B.V. All rights reserved.
AB - The main goal of the study was to predict individual patients' future mental healthcare consumption, and thereby enhancing the design of an efficient demand-oriented mental healthcare system by focusing on a patient population associated with intensive mental healthcare consumption. Factors that affect the mental healthcare consumption of service users with non-affective psychosis were identified, and subsequently used in a prognostic model to predict future healthcare consumption.This study was a secondary analysis of an existing dataset from the GROUP study. Based on mental healthcare consumption, patients with non-affective psychosis were divided into two groups: low (N = 579) and high (N = 488) intensive mental healthcare consumers. Three different techniques from the field of machine learning were applied on crosssectional data to identify risk factors: logistic regression, classification tree and a random forest. Subsequently, the same techniques were applied longitudinally in order to predict future healthcare consumption.Identified variables that affected healthcare consumption were the number of psychotic episodes, paid employment, engagement in social activities, previous healthcare consumption, and met needs. Analyses showed that the random forest method is best suited to model risk factors, and that these relations predict future healthcare consumption (AUC 0.71, PPV 0.65).Machine learning techniques provide valuable information for identifying risk factors in psychosis. They may thus help clinicians optimize allocation of mental healthcare resources by predicting future healthcare consumption.Copyright © 2020 Elsevier B.V. All rights reserved.
KW - COGNITIVE-BEHAVIORAL THERAPY
KW - SUBSTANCE USE
KW - FOLLOW-UP
KW - HIGH-RISK
KW - ANTIPSYCHOTIC MEDICATION
KW - FAMILY INTERVENTION
KW - UNTREATED PSYCHOSIS
KW - SERVICE USE
KW - SCHIZOPHRENIA
KW - HOSPITALIZATION
U2 - 10.1016/j.schres.2020.01.008
DO - 10.1016/j.schres.2020.01.008
M3 - Article
C2 - 32146025
SN - 0920-9964
VL - 218
SP - 166
EP - 172
JO - Schizophrenia Research
JF - Schizophrenia Research
ER -