Use of deep learning methods to translate drug-induced gene expression changes from rat to human primary hepatocytes

Shauna D O'Donovan*, Kurt Driessens, Daniel Lopatta, Florian Wimmenauer, Alexander Lukas, Jelmer Neeven, Tobias Stumm, Evgueni Smirnov, Michael Lenz, Gokhan Ertaylan, Danyel G J Jennen, Natal A W van Riel, Rachel Cavill, Ralf L M Peeters, Theo M C M de Kok

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numbere0236392
Number of pages20
JournalPLOS ONE
Volume15
Issue number8
DOIs
Publication statusPublished - 11 Aug 2020

Keywords

  • REPRESENTATIONS
  • TOXICOGENOMICS
  • TOXICOLOGY
  • TOXICITY

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