Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours

Alexandra M. Mowday; Ludwig J. Dubois; Aleksandra M. Kubiak; Jasmine V. E. Chan-Hyams; Christopher P. Guise; Amir Ashoorzadeh; Philippe Lambin; David F. Ackerley; Jeff B. Smaill; Nigel P. Minton; Jan Theys; Adam V. Patterson

doi:10.1038/s41417-021-00296-7

Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours

Alexandra M. Mowday, Ludwig J. Dubois, Aleksandra M. Kubiak, Jasmine V. E. Chan-Hyams, Christopher P. Guise, Amir Ashoorzadeh, Philippe Lambin, David F. Ackerley, Jeff B. Smaill, Nigel P. Minton, Jan Theys, Adam V. Patterson^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Web of Science)

10 Downloads (Pure)

Original language	English
Number of pages	11
Journal	Cancer Gene Therapy
DOIs	https://doi.org/10.1038/s41417-021-00296-7
Publication status	E-pub ahead of print - 8 Feb 2021

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10.1038/s41417-021-00296-7

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Mowday, A. M., Dubois, L. J., Kubiak, A. M., Chan-Hyams, J. V. E., Guise, C. P., Ashoorzadeh, A., Lambin, P., Ackerley, D. F., Smaill, J. B., Minton, N. P., Theys, J., & Patterson, A. V. (2021). Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours. Cancer Gene Therapy. https://doi.org/10.1038/s41417-021-00296-7

Mowday, Alexandra M. ; Dubois, Ludwig J. ; Kubiak, Aleksandra M. ; Chan-Hyams, Jasmine V. E. ; Guise, Christopher P. ; Ashoorzadeh, Amir ; Lambin, Philippe ; Ackerley, David F. ; Smaill, Jeff B. ; Minton, Nigel P. ; Theys, Jan ; Patterson, Adam V. / Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours. In: Cancer Gene Therapy. 2021.

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title = "Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours",

author = "Mowday, {Alexandra M.} and Dubois, {Ludwig J.} and Kubiak, {Aleksandra M.} and Chan-Hyams, {Jasmine V. E.} and Guise, {Christopher P.} and Amir Ashoorzadeh and Philippe Lambin and Ackerley, {David F.} and Smaill, {Jeff B.} and Minton, {Nigel P.} and Jan Theys and Patterson, {Adam V.}",

year = "2021",

month = feb,

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doi = "10.1038/s41417-021-00296-7",

language = "English",

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Mowday, AM, Dubois, LJ, Kubiak, AM, Chan-Hyams, JVE, Guise, CP, Ashoorzadeh, A, Lambin, P, Ackerley, DF, Smaill, JB, Minton, NP, Theys, J & Patterson, AV 2021, 'Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours', Cancer Gene Therapy. https://doi.org/10.1038/s41417-021-00296-7

Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours. / Mowday, Alexandra M.; Dubois, Ludwig J.; Kubiak, Aleksandra M.; Chan-Hyams, Jasmine V. E.; Guise, Christopher P.; Ashoorzadeh, Amir; Lambin, Philippe; Ackerley, David F.; Smaill, Jeff B.; Minton, Nigel P.; Theys, Jan; Patterson, Adam V.

In: Cancer Gene Therapy, 08.02.2021.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Mowday, Alexandra M.

AU - Dubois, Ludwig J.

AU - Kubiak, Aleksandra M.

AU - Chan-Hyams, Jasmine V. E.

AU - Guise, Christopher P.

AU - Ashoorzadeh, Amir

AU - Lambin, Philippe

AU - Ackerley, David F.

AU - Smaill, Jeff B.

AU - Minton, Nigel P.

AU - Theys, Jan

AU - Patterson, Adam V.

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