TY - JOUR
T1 - Unifying the identification of biomedical entities with the Bioregistry
AU - Hoyt, Charles Tapley
AU - Balk, Meghan
AU - Callahan, Tiffany J
AU - Domingo-Fernández, Daniel
AU - Haendel, Melissa A
AU - Hegde, Harshad B
AU - Himmelstein, Daniel S
AU - Karis, Klas
AU - Kunze, John
AU - Lubiana, Tiago
AU - Matentzoglu, Nicolas
AU - McMurry, Julie
AU - Moxon, Sierra
AU - Mungall, Christopher J
AU - Rutz, Adriano
AU - Unni, Deepak R
AU - Willighagen, Egon
AU - Winston, Donald
AU - Gyori, Benjamin M
N1 - © 2022. The Author(s).
PY - 2022/11/19
Y1 - 2022/11/19
N2 - The standardized identification of biomedical entities is a cornerstone of interoperability, reuse, and data integration in the life sciences. Several registries have been developed to catalog resources maintaining identifiers for biomedical entities such as small molecules, proteins, cell lines, and clinical trials. However, existing registries have struggled to provide sufficient coverage and metadata standards that meet the evolving needs of modern life sciences researchers. Here, we introduce the Bioregistry, an integrative, open, community-driven metaregistry that synthesizes and substantially expands upon 23 existing registries. The Bioregistry addresses the need for a sustainable registry by leveraging public infrastructure and automation, and employing a progressive governance model centered around open code and open data to foster community contribution. The Bioregistry can be used to support the standardized annotation of data, models, ontologies, and scientific literature, thereby promoting their interoperability and reuse. The Bioregistry can be accessed through https://bioregistry.io and its source code and data are available under the MIT and CC0 Licenses at https://github.com/biopragmatics/bioregistry .
AB - The standardized identification of biomedical entities is a cornerstone of interoperability, reuse, and data integration in the life sciences. Several registries have been developed to catalog resources maintaining identifiers for biomedical entities such as small molecules, proteins, cell lines, and clinical trials. However, existing registries have struggled to provide sufficient coverage and metadata standards that meet the evolving needs of modern life sciences researchers. Here, we introduce the Bioregistry, an integrative, open, community-driven metaregistry that synthesizes and substantially expands upon 23 existing registries. The Bioregistry addresses the need for a sustainable registry by leveraging public infrastructure and automation, and employing a progressive governance model centered around open code and open data to foster community contribution. The Bioregistry can be used to support the standardized annotation of data, models, ontologies, and scientific literature, thereby promoting their interoperability and reuse. The Bioregistry can be accessed through https://bioregistry.io and its source code and data are available under the MIT and CC0 Licenses at https://github.com/biopragmatics/bioregistry .
U2 - 10.1038/s41597-022-01807-3
DO - 10.1038/s41597-022-01807-3
M3 - Article
C2 - 36402838
SN - 2052-4463
VL - 9
JO - Scientific data
JF - Scientific data
IS - 1
M1 - 714
ER -