Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma

Sven van den Bosch; Tim Dijkema; Martina C. Kunze-Busch; Chris H. J. Terhaard; Cornelis P. J. Raaijmakers; Patricia A. H. Doornaert; Frank J. P. Hoebers; Marije R. Vergeer; Bas Kreike; Oda B. Wijers; Wim J. G. Oyen; Johannes H. A. M. Kaanders

doi:10.1186/s12885-017-3195-7

Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma

Sven van den Bosch^*, Tim Dijkema, Martina C. Kunze-Busch, Chris H. J. Terhaard, Cornelis P. J. Raaijmakers, Patricia A. H. Doornaert, Frank J. P. Hoebers, Marije R. Vergeer, Bas Kreike, Oda B. Wijers, Wim J. G. Oyen, Johannes H. A. M. Kaanders

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	208
Number of pages	8
Journal	BMC Cancer
Volume	17
DOIs	https://doi.org/10.1186/s12885-017-3195-7
Publication status	Published - 21 Mar 2017

Keywords

Head and neck cancer
Squamous cell carcinoma
Accelerated radiation therapy
Dose reduction
Dose de-escalation
Elective nodes
FDG-PET
Euality of life
QUALITY-OF-LIFE
TROG CONSENSUS GUIDELINES
CANCER PATIENTS
RESPONSE RELATIONSHIP
OROPHARYNGEAL CANCER
NCIC CTG
RADIOTHERAPY
THERAPY
ONCOLOGY
EORTC

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10.1186/s12885-017-3195-7

Cite this

van den Bosch, S., Dijkema, T., Kunze-Busch, M. C., Terhaard, C. H. J., Raaijmakers, C. P. J., Doornaert, P. A. H., Hoebers, F. J. P., Vergeer, M. R., Kreike, B., Wijers, O. B., Oyen, W. J. G., & Kaanders, J. H. A. M. (2017). Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma. BMC Cancer, 17, [208]. https://doi.org/10.1186/s12885-017-3195-7

van den Bosch, Sven ; Dijkema, Tim ; Kunze-Busch, Martina C. ; Terhaard, Chris H. J. ; Raaijmakers, Cornelis P. J. ; Doornaert, Patricia A. H. ; Hoebers, Frank J. P. ; Vergeer, Marije R. ; Kreike, Bas ; Wijers, Oda B. ; Oyen, Wim J. G. ; Kaanders, Johannes H. A. M. / Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT) : study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma. In: BMC Cancer. 2017 ; Vol. 17.

@article{f724d352bf35498aa05296969a26bf9f,

title = "Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma",

keywords = "Head and neck cancer, Squamous cell carcinoma, Accelerated radiation therapy, Dose reduction, Dose de-escalation, Elective nodes, FDG-PET, Euality of life, QUALITY-OF-LIFE, TROG CONSENSUS GUIDELINES, CANCER PATIENTS, RESPONSE RELATIONSHIP, OROPHARYNGEAL CANCER, NCIC CTG, RADIOTHERAPY, THERAPY, ONCOLOGY, EORTC",

author = "{van den Bosch}, Sven and Tim Dijkema and Kunze-Busch, {Martina C.} and Terhaard, {Chris H. J.} and Raaijmakers, {Cornelis P. J.} and Doornaert, {Patricia A. H.} and Hoebers, {Frank J. P.} and Vergeer, {Marije R.} and Bas Kreike and Wijers, {Oda B.} and Oyen, {Wim J. G.} and Kaanders, {Johannes H. A. M.}",

year = "2017",

month = mar,

day = "21",

doi = "10.1186/s12885-017-3195-7",

language = "English",

volume = "17",

journal = "BMC Cancer",

issn = "1471-2407",

publisher = "BioMed Central Ltd",

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van den Bosch, S, Dijkema, T, Kunze-Busch, MC, Terhaard, CHJ, Raaijmakers, CPJ, Doornaert, PAH, Hoebers, FJP, Vergeer, MR, Kreike, B, Wijers, OB, Oyen, WJG & Kaanders, JHAM 2017, 'Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma', BMC Cancer, vol. 17, 208. https://doi.org/10.1186/s12885-017-3195-7

Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT) : study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma. / van den Bosch, Sven; Dijkema, Tim; Kunze-Busch, Martina C.; Terhaard, Chris H. J.; Raaijmakers, Cornelis P. J.; Doornaert, Patricia A. H.; Hoebers, Frank J. P.; Vergeer, Marije R.; Kreike, Bas; Wijers, Oda B.; Oyen, Wim J. G.; Kaanders, Johannes H. A. M.

In: BMC Cancer, Vol. 17, 208, 21.03.2017.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT)

T2 - study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma

AU - van den Bosch, Sven

AU - Dijkema, Tim

AU - Kunze-Busch, Martina C.

AU - Terhaard, Chris H. J.

AU - Raaijmakers, Cornelis P. J.

AU - Doornaert, Patricia A. H.

AU - Hoebers, Frank J. P.

AU - Vergeer, Marije R.

AU - Kreike, Bas

AU - Wijers, Oda B.

AU - Oyen, Wim J. G.

AU - Kaanders, Johannes H. A. M.

PY - 2017/3/21

Y1 - 2017/3/21

KW - Head and neck cancer

KW - Squamous cell carcinoma

KW - Accelerated radiation therapy

KW - Dose reduction

KW - Dose de-escalation

KW - Elective nodes

KW - FDG-PET

KW - Euality of life

KW - QUALITY-OF-LIFE

KW - TROG CONSENSUS GUIDELINES

KW - CANCER PATIENTS

KW - RESPONSE RELATIONSHIP

KW - OROPHARYNGEAL CANCER

KW - NCIC CTG

KW - RADIOTHERAPY

KW - THERAPY

KW - ONCOLOGY

KW - EORTC

U2 - 10.1186/s12885-017-3195-7

DO - 10.1186/s12885-017-3195-7

M3 - Article

VL - 17

JO - BMC Cancer

JF - BMC Cancer

SN - 1471-2407

M1 - 208

ER -

van den Bosch S, Dijkema T, Kunze-Busch MC, Terhaard CHJ, Raaijmakers CPJ, Doornaert PAH et al. Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma. BMC Cancer. 2017 Mar 21;17. 208. https://doi.org/10.1186/s12885-017-3195-7