Abstract
Background-The present study was aimed at determining the impact of type 2 diabetes mellitus (DM) on postoperative bioprosthetic structural valve degeneration. Methods and Results-Twelve Italian centers participated in the study. Patient data refer to bioprosthetic implantations performed from November 1988 to December 2009, which resulted in 6184 patients (mean age 71.3+/-5.4 years, 60.1% male) being enrolled. Of these patients, 1731 (27.9%) had type 2 DM. The propensity score-matching algorithm successfully matched 1113 patients with type 2 DM with the same number of no-DM patients. The postmatching standard differences were less than 0.1 for each of the covariates, and 64.2% of DM patients were matched. The early (30 days) mortality rate was 7.8% (n=87) versus 2.9% (n=33) in patients with or without type 2 DM (P
Original language | English |
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Pages (from-to) | 604-614 |
Journal | Circulation |
Volume | 125 |
Issue number | 4 |
DOIs | |
Publication status | Published - 31 Jan 2012 |
Keywords
- heart valve surgery
- prosthetic heart valves
- type 2 diabetes mellitus