Tumour Shrinkage and Good Facial Nerve Function After Planned Partial Resection and Gamma Knife Radiosurgery in Koos 4 Vestibular Schwannoma

Mohammed Al-ahmari, Max Keizer*, Bander Al-dhafery, Danielle Eekers, Koos Hovinga, Henricus Kunst, Yasin Temel

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

AIM: To evaluate clinical and radiological outcome in surgically treated Koos 4 vestibular schwannomas. MATERIAL and METHODS: Volumetric analysis of the tumour volumes before surgery, after surgery (before radiation), and at follow-up time-points after radiation was performed. Clinical data on facial nerve function and complications were collected. Approximately 6 months after surgery, all patients were treated with a single fraction of stereotactic radiosurgery using the gamma knife radiosurgery with a mean marginal dose of 12.9 Gy to the residual tumour volume. RESULTS: Mean tumour volume was 11.64 cm(3) which was reduced to a mean volume of 4.17 cm(3) after partial resection. After a mean follow-up of 100 months, residual tumour showed a decrease in volume in 20 patients, stable disease in one patient and two patients showed progressive tumour volume requiring a second operation in one patient. Facial nerve function was preserved in all patients. One patient suffered from a trigeminal neuralgia after radiation. CONCLUSION: Planned partial resection followed by radiation for patients with Koos 4 vestibular schwannoma is an effective strategy to preserve facial nerve function and achieve tumour control. Residual tumours after planned partial resection showed a mean decrease in volume of 50% at the last follow-up time point.
Original languageEnglish
Pages (from-to)265-273
Number of pages9
JournalTurkish Neurosurgery
Volume35
Issue number2
DOIs
Publication statusPublished - 2025

Keywords

  • Vestibular schwannoma
  • Partial resection
  • Gamma knife
  • Tumour volume
  • Facial nerve
  • SUBTOTAL RESECTION
  • ACOUSTIC NEUROMA
  • FOLLOW-UP
  • STEREOTACTIC RADIOTHERAPY
  • VOLUME CHANGES
  • SURGERY
  • MANAGEMENT
  • GROWTH
  • PRESERVATION
  • EXPERIENCE

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