TY - JOUR
T1 - Trends in the prognosis of patients with primary metastatic breast cancer diagnosed between 1975 and 2002
AU - Ernst, M.F.
AU - van de Poll-Franse, L.V.
AU - Roukema, J.A.
AU - Coebergh, J.W.W.
AU - van Gestel, C.M.J.
AU - Vreugdenhil, G.
AU - Louwman, M.J.
AU - Voogd, A.C.
PY - 2007/1/1
Y1 - 2007/1/1
N2 - We performed a population-based study, including 1089 patients with primary metastatic breast cancer, diagnosed in South-East Netherlands between 1975 and 2002, and tried to give an answer to the question if prognosis of this patient group has improved or not. Follow-up was completed until 1 January 2005. The median survival times for patients with primary metastatic disease were 18, 17 and 20.5 months for patients diagnosed in the periods 1975-1984, 1985-1994 and 1995-2002, respectively. A multivariate analysis, including age, tumour size and information on the localization of metastatic disease and the number of metastatic sites, showed that patients diagnosed in the period 1995-2002 had a 18% tower death risk (95% confidence interval 5-30) compared to those diagnosed in the period 1985-1994. These data show that the prognosis of patients with primary metastatic breast cancer remained unchanged between 1975 and 1994 and that some progress has been made after 1994.
AB - We performed a population-based study, including 1089 patients with primary metastatic breast cancer, diagnosed in South-East Netherlands between 1975 and 2002, and tried to give an answer to the question if prognosis of this patient group has improved or not. Follow-up was completed until 1 January 2005. The median survival times for patients with primary metastatic disease were 18, 17 and 20.5 months for patients diagnosed in the periods 1975-1984, 1985-1994 and 1995-2002, respectively. A multivariate analysis, including age, tumour size and information on the localization of metastatic disease and the number of metastatic sites, showed that patients diagnosed in the period 1995-2002 had a 18% tower death risk (95% confidence interval 5-30) compared to those diagnosed in the period 1985-1994. These data show that the prognosis of patients with primary metastatic breast cancer remained unchanged between 1975 and 1994 and that some progress has been made after 1994.
U2 - 10.1016/j.breast.2007.01.001
DO - 10.1016/j.breast.2007.01.001
M3 - Article
C2 - 17303426
SN - 0960-9776
VL - 16
SP - 344
EP - 351
JO - Breast
JF - Breast
IS - 4
ER -