TY - JOUR
T1 - Trends in the Incidence of Bowen Disease Based on a Single-Center Study in the Netherlands
AU - Jansen, Maud H. E.
AU - Ozhan-Hasan, Hilal
AU - Nelemans, Patty J.
AU - Winnepenninckx, Veronique J.
AU - Mosterd, Klara
N1 - Publisher Copyright:
© 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.
PY - 2019/11
Y1 - 2019/11
N2 - BACKGROUND Incidence trends of nonmelanoma skin cancer show an increase. Few data have been published about the incidence of Bowen disease (BD). Three previous studies, conducted more than 15 years ago in North America, found large variation in incidence rates in Caucasians, and trends over longer periods have never been studied.OBJECTIVE To estimate the incidence of BD in a Caucasian population in Northern Europe (Maastricht, the Netherlands) between 2003 and 2013.METHODS Primary and histologically confirmed BD, diagnosed in Maastricht, the Netherlands, in the years 2003, 2008, and 2013, was retrieved from a pathology database. Age-standardized and sex-specific incidence rates per 100,000 inhabitants were calculated by using the age distribution of the European standard population of 2013.RESULTS A statistically significant increase in the annual age-standardized incidence rates per 100,000 people was found from 8.1 (95% confidence interval [CI] 3.7-12.5) in 2003 to 68.9 (95% CI 57.2-80.7) in 2013 (p <.001). For women, there was an increase from 7.7/100,000 (95% CI 2.0-13.4) in 2003 to 76.8/100,000 (95% CI 60.2-93.5) in 2013, respectively (p <.001). An increase from 8.8/100,000 (95% CI 1.8-15.9) in 2003 to 59.2/100,000 men (95% CI 42.8-75.6) in 2013 (p <.001) was found.CONCLUSION These findings suggest an increase in the annual age-standardized incidence rates in BD.
AB - BACKGROUND Incidence trends of nonmelanoma skin cancer show an increase. Few data have been published about the incidence of Bowen disease (BD). Three previous studies, conducted more than 15 years ago in North America, found large variation in incidence rates in Caucasians, and trends over longer periods have never been studied.OBJECTIVE To estimate the incidence of BD in a Caucasian population in Northern Europe (Maastricht, the Netherlands) between 2003 and 2013.METHODS Primary and histologically confirmed BD, diagnosed in Maastricht, the Netherlands, in the years 2003, 2008, and 2013, was retrieved from a pathology database. Age-standardized and sex-specific incidence rates per 100,000 inhabitants were calculated by using the age distribution of the European standard population of 2013.RESULTS A statistically significant increase in the annual age-standardized incidence rates per 100,000 people was found from 8.1 (95% confidence interval [CI] 3.7-12.5) in 2003 to 68.9 (95% CI 57.2-80.7) in 2013 (p <.001). For women, there was an increase from 7.7/100,000 (95% CI 2.0-13.4) in 2003 to 76.8/100,000 (95% CI 60.2-93.5) in 2013, respectively (p <.001). An increase from 8.8/100,000 (95% CI 1.8-15.9) in 2003 to 59.2/100,000 men (95% CI 42.8-75.6) in 2013 (p <.001) was found.CONCLUSION These findings suggest an increase in the annual age-standardized incidence rates in BD.
KW - SQUAMOUS-CELL CARCINOMA
KW - RISK
U2 - 10.1097/DSS.0000000000001980
DO - 10.1097/DSS.0000000000001980
M3 - Article
C2 - 31274528
SN - 1076-0512
VL - 45
SP - 1353
EP - 1358
JO - Dermatologic Surgery
JF - Dermatologic Surgery
IS - 11
ER -