Trehalose augments autophagy to mitigate stress induced inflammation in human corneal cells

Trailokyanath Panigrahi, Shivapriya Shivakumar, Rohit Shetty, Sharon D'souza, Everette Jacob Remington Nelson, Swaminathan Sethu, Nallathambi Jeyabalan, Arkasubhra Ghosh

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)699-713
Number of pages15
JournalOcular Surface
Volume17
Issue number4
DOIs
Publication statusPublished - Oct 2019

Keywords

  • Corneal inflammation
  • Desiccation stress
  • TNF-alpha
  • Dry eye
  • Autophagy
  • Trehalose
  • NECROSIS-FACTOR-ALPHA
  • DRY EYE DISEASE
  • EPITHELIAL-CELLS
  • TNF-ALPHA
  • KERATOCONUS PATIENTS
  • EXPRESSION
  • APOPTOSIS
  • FIBROBLASTS
  • KERATOCYTES
  • INHIBITION

Cite this

Panigrahi, T., Shivakumar, S., Shetty, R., D'souza, S., Nelson, E. J. R., Sethu, S., Jeyabalan, N., & Ghosh, A. (2019). Trehalose augments autophagy to mitigate stress induced inflammation in human corneal cells. Ocular Surface, 17(4), 699-713. https://doi.org/10.1016/j.jtos.2019.08.004