Trehalose augments autophagy to mitigate stress induced inflammation in human corneal cells

Trailokyanath Panigrahi, Shivapriya Shivakumar, Rohit Shetty, Sharon D'souza, Everette Jacob Remington Nelson, Swaminathan Sethu, Nallathambi Jeyabalan*, Arkasubhra Ghosh*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)699-713
Number of pages15
JournalOcular Surface
Volume17
Issue number4
DOIs
Publication statusPublished - Oct 2019

Keywords

  • Corneal inflammation
  • Desiccation stress
  • TNF-alpha
  • Dry eye
  • Autophagy
  • Trehalose
  • NECROSIS-FACTOR-ALPHA
  • DRY EYE DISEASE
  • EPITHELIAL-CELLS
  • TNF-ALPHA
  • KERATOCONUS PATIENTS
  • EXPRESSION
  • APOPTOSIS
  • FIBROBLASTS
  • KERATOCYTES
  • INHIBITION

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