TY - JOUR
T1 - Treatment of urinary incontinence in women with chronic obstructive pulmonary updates disease
T2 - a randomised controlled study
AU - Haukeland-Parker, S.
AU - Frisk, B.
AU - Spruit, M.A.
AU - Stafne, S.N.
AU - Johannessen, H.H.
N1 - Funding Information:
This work was supported by the Østfold Hospital Trust under Grant AB3342. The role of the funding body was to contribute and support the design of the study, the collection, analysis, and interpretation of data, and two authors from ØHT were involved in writing the manuscript.
Funding Information:
The authors wish to thank all the women who participated in the study, and the physiotherapists who contributed to the conduction of the study, especially Karen Thomas, Inger Storr?seter, Clara Karoliussen, Julia Trevor, Linda S?rby, Hilde Thorsen and Mats Westerfjell Grensemo. In addition, many thanks to Eivind Hasvik for his contribution with graphics and to Hanne Fj?ll Larssen for performing the lung function tests.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021/12/11
Y1 - 2021/12/11
N2 - Background: Little is known regarding treatment of urinary incontinence (UI) in women with chronic obstructive pulmonary disease (COPD). The aim of the study was to explore the efficacy of pelvic floor muscle training (PFMT) or cough-suppression techniques (CST) on UI in women with COPD.Methods: A three-armed, two-centred, single-blinded, randomised controlled study was performed. Subjects were randomised to (a) PFMT for 16 weeks, (b) 2-3 educational sessions in CST, or (c) written information only. All participants completed questionnaires about UI, cough symptoms, and health status and underwent clinical examinations to evaluate the strength of the pelvic floor muscles and exercise capacity. Daily physical activity levels were measured using an activity monitor and lung function with spirometry. With a significance level of 5% and an 80% chance of detecting a significant difference between groups of 2.5 points on the ICIQ UI SF score, our sample size calculation showed that a total of 78 women, 26 in each group, was required to complete the study.Results: During the period 2016 to 2018, 95 women were invited to the study. A total of 42 were recruited, three were excluded and 10 (24%) dropped out during the follow-up period. Mean ICIQ-UI SF total baseline score was 9.6 (range: 1-17) and 7.0 (range: 0-16) at follow-up. Changes in subjective UI as measured with the ICIQ-UI SF questionnaire were seen in the PFMT group and control group, but not in the CST group.Conclusion: Due to the low number of available participants and recruitment difficulties including practical issues such as travel distance, lack of interest, poor state of health, and high number of comorbidities, our results are inconclusive. However, reduced subjective UI was observed in the PFMT and control groups with a trend towards best effect in the PFMT group. Screening for UI is advisable in all women with COPD to be able to identify and treat these women to reduce symptom burden and improve quality of life. Future studies should focus on barriers to recruitment as well as randomised controlled studies with larger sample sizes.
AB - Background: Little is known regarding treatment of urinary incontinence (UI) in women with chronic obstructive pulmonary disease (COPD). The aim of the study was to explore the efficacy of pelvic floor muscle training (PFMT) or cough-suppression techniques (CST) on UI in women with COPD.Methods: A three-armed, two-centred, single-blinded, randomised controlled study was performed. Subjects were randomised to (a) PFMT for 16 weeks, (b) 2-3 educational sessions in CST, or (c) written information only. All participants completed questionnaires about UI, cough symptoms, and health status and underwent clinical examinations to evaluate the strength of the pelvic floor muscles and exercise capacity. Daily physical activity levels were measured using an activity monitor and lung function with spirometry. With a significance level of 5% and an 80% chance of detecting a significant difference between groups of 2.5 points on the ICIQ UI SF score, our sample size calculation showed that a total of 78 women, 26 in each group, was required to complete the study.Results: During the period 2016 to 2018, 95 women were invited to the study. A total of 42 were recruited, three were excluded and 10 (24%) dropped out during the follow-up period. Mean ICIQ-UI SF total baseline score was 9.6 (range: 1-17) and 7.0 (range: 0-16) at follow-up. Changes in subjective UI as measured with the ICIQ-UI SF questionnaire were seen in the PFMT group and control group, but not in the CST group.Conclusion: Due to the low number of available participants and recruitment difficulties including practical issues such as travel distance, lack of interest, poor state of health, and high number of comorbidities, our results are inconclusive. However, reduced subjective UI was observed in the PFMT and control groups with a trend towards best effect in the PFMT group. Screening for UI is advisable in all women with COPD to be able to identify and treat these women to reduce symptom burden and improve quality of life. Future studies should focus on barriers to recruitment as well as randomised controlled studies with larger sample sizes.
KW - Chronic obstructive pulmonary disease
KW - Urinary incontinence
KW - Pelvic floor muscle training
KW - Coughsuppression therapy
KW - QUALITY-OF-LIFE
KW - FIELD WALKING TESTS
KW - PHYSICAL-ACTIVITY
KW - COUGH
KW - PREVALENCE
KW - IMPACT
KW - TERMINOLOGY
KW - PROGRESSION
KW - STATEMENT
KW - SYMPTOMS
U2 - 10.1186/s13063-021-05816-2
DO - 10.1186/s13063-021-05816-2
M3 - Article
C2 - 34895285
SN - 1745-6215
VL - 22
JO - Trials
JF - Trials
IS - 1
M1 - 900
ER -