Treating winter depressive episodes in bipolar disorder: an open trial of light therapy

Lotte J. E. van Hout; Lisette E. P. Rops; Claudia J. P. Simons

doi:10.1186/s40345-020-00182-5

Treating winter depressive episodes in bipolar disorder: an open trial of light therapy

Lotte J. E. van Hout^*, Lisette E. P. Rops, Claudia J. P. Simons

^*Corresponding author for this work

MHeNs - Cognitive Neuropsychiatry and Clinical Neuroscience

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Web of Science)

Abstract

Background Light therapy has been used to treat winter depression in bipolar disorder, although the dose, duration, and timing of treatment have differed. The present study is an open trial of light therapy for depressive episodes in autumn/winter using a Dutch protocol specific for patients with a bipolar disorder. Methods Data were collected for the seasons September-April 2017-2018 and September-April 2018-2019. In total, 58 patients received light therapy for a minimum of 7 days and a maximum of 21 days; there was a follow-up measurement after two weeks. Outcomes were quick inventory of depressive symptomatology (QIDS) scores and side effects. Results QIDS scores were significantly lower at the last day of therapy (B = - 6.00, p <0.001) and 2 weeks after the end of treatment (B = - 6.55, p <0.001) compared with pre-intervention. Remission (QIDS

Original language	English
Article number	17
Number of pages	7
Journal	International Journal of Bipolar Disorders
Volume	8
Issue number	1
DOIs	https://doi.org/10.1186/s40345-020-00182-5
Publication status	Published - 1 Jun 2020

Keywords

Light therapy
Bipolar disorder
Seasonal affective disorder
Winter depression
SEASONAL AFFECTIVE-DISORDER
REPORT QIDS-SR
BRIGHT LIGHT
QUICK INVENTORY
NONSEASONAL DEPRESSION
SLEEP-DEPRIVATION
MOOD DISORDERS
EARLY RESPONSE
DOUBLE-BLIND
EFFICACY

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Cite this

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title = "Treating winter depressive episodes in bipolar disorder: an open trial of light therapy",

abstract = "Background Light therapy has been used to treat winter depression in bipolar disorder, although the dose, duration, and timing of treatment have differed. The present study is an open trial of light therapy for depressive episodes in autumn/winter using a Dutch protocol specific for patients with a bipolar disorder. Methods Data were collected for the seasons September-April 2017-2018 and September-April 2018-2019. In total, 58 patients received light therapy for a minimum of 7 days and a maximum of 21 days; there was a follow-up measurement after two weeks. Outcomes were quick inventory of depressive symptomatology (QIDS) scores and side effects. Results QIDS scores were significantly lower at the last day of therapy (B = - 6.00, p <0.001) and 2 weeks after the end of treatment (B = - 6.55, p <0.001) compared with pre-intervention. Remission (QIDS",

keywords = "Light therapy, Bipolar disorder, Seasonal affective disorder, Winter depression, SEASONAL AFFECTIVE-DISORDER, REPORT QIDS-SR, BRIGHT LIGHT, QUICK INVENTORY, NONSEASONAL DEPRESSION, SLEEP-DEPRIVATION, MOOD DISORDERS, EARLY RESPONSE, DOUBLE-BLIND, EFFICACY",

author = "{van Hout}, {Lotte J. E.} and Rops, {Lisette E. P.} and Simons, {Claudia J. P.}",

year = "2020",

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doi = "10.1186/s40345-020-00182-5",

language = "English",

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journal = "International Journal of Bipolar Disorders",

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T2 - an open trial of light therapy

AU - van Hout, Lotte J. E.

AU - Rops, Lisette E. P.

AU - Simons, Claudia J. P.

PY - 2020/6/1

Y1 - 2020/6/1

N2 - Background Light therapy has been used to treat winter depression in bipolar disorder, although the dose, duration, and timing of treatment have differed. The present study is an open trial of light therapy for depressive episodes in autumn/winter using a Dutch protocol specific for patients with a bipolar disorder. Methods Data were collected for the seasons September-April 2017-2018 and September-April 2018-2019. In total, 58 patients received light therapy for a minimum of 7 days and a maximum of 21 days; there was a follow-up measurement after two weeks. Outcomes were quick inventory of depressive symptomatology (QIDS) scores and side effects. Results QIDS scores were significantly lower at the last day of therapy (B = - 6.00, p <0.001) and 2 weeks after the end of treatment (B = - 6.55, p <0.001) compared with pre-intervention. Remission (QIDS

AB - Background Light therapy has been used to treat winter depression in bipolar disorder, although the dose, duration, and timing of treatment have differed. The present study is an open trial of light therapy for depressive episodes in autumn/winter using a Dutch protocol specific for patients with a bipolar disorder. Methods Data were collected for the seasons September-April 2017-2018 and September-April 2018-2019. In total, 58 patients received light therapy for a minimum of 7 days and a maximum of 21 days; there was a follow-up measurement after two weeks. Outcomes were quick inventory of depressive symptomatology (QIDS) scores and side effects. Results QIDS scores were significantly lower at the last day of therapy (B = - 6.00, p <0.001) and 2 weeks after the end of treatment (B = - 6.55, p <0.001) compared with pre-intervention. Remission (QIDS

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