Traumatic stress and accelerated DNA methylation age: A meta-analysis

Erika J. Wolf, Hannah Maniates, Nicole Nugent, Adam X. Maihofer, Don Armstrong, Andrew Ratanatharathorn, Allison E. Ashley-Koch, Melanie Garrett, Nathan A. Kimbrel, Adriana Lori, Allison E. Aiello, Dewleen G. Baker, Jean C. Beckham, Marco P. Boks, Sandro Galea, Elbert Geuze, Michael A. Hauser, Ronald C. Kessler, Karestan C. Koenen, Mark W. MillerKerry J. Ressler, Victoria Risbrough, Bart P. P. Rutten, Murray B. Stein, Robert J. Ursano, Eric Vermetten, Christiaan H. Vinkers, Monica Uddin, Alicia K. Smith, Caroline M. Nievergelt, Mark W. Logue, VA Mid-Atlantic MIRECC Workgrp

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)123-134
Number of pages12
JournalPsychoneuroendocrinology
Volume92
DOIs
Publication statusPublished - 1 Jun 2018

Keywords

  • DNA methylation
  • Traumatic stress
  • PTSD
  • Accelerated aging
  • Meta-analysis
  • Epigenetic clock
  • GENOME-WIDE ASSOCIATION
  • INTERNATIONAL DIAGNOSTIC INTERVIEW
  • INDIVIDUAL PARTICIPANT DATA
  • EPIGENETIC CLOCK ANALYSIS
  • PSYCHOMETRIC PROPERTIES
  • TELOMERE LENGTH
  • CORTICAL THICKNESS
  • MENTAL-HEALTH
  • PATIENT DATA
  • DISORDER
  • RESILIENCE
  • INVENTORY
  • Epigenesis, Genetic
  • Humans
  • Middle Aged
  • Male
  • DNA Methylation
  • Stress Disorders, Post-Traumatic/genetics
  • Adult
  • Female
  • Genetic Predisposition to Disease
  • Trauma Severity Indices
  • Cohort Studies

Cite this

Wolf, E. J., Maniates, H., Nugent, N., Maihofer, A. X., Armstrong, D., Ratanatharathorn, A., Ashley-Koch, A. E., Garrett, M., Kimbrel, N. A., Lori, A., Aiello, A. E., Baker, D. G., Beckham, J. C., Boks, M. P., Galea, S., Geuze, E., Hauser, M. A., Kessler, R. C., Koenen, K. C., ... VA Mid-Atlantic MIRECC Workgrp (2018). Traumatic stress and accelerated DNA methylation age: A meta-analysis. Psychoneuroendocrinology, 92, 123-134. https://doi.org/10.1016/j.psyneuen.2017.12.007