Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

Giacomo Salvadore, Pascal Bonaventure*, Anantha Shekhar, Philip L. Johnson, Brian Lord, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Christine Dugovic, Sander Brooks, Rob Zuiker, Cathy Bleys, Kanaka Tatikola, Bart Remmerie, Gabriel E. Jacobs, Koen Schruers, John Moyer, Abigail Nash, Luc G. M. Van Nueten, Wayne C. Drevets

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number308
Number of pages10
JournalTranslational Psychiatry
Volume10
Issue number1
DOIs
Publication statusPublished - 7 Sep 2020

Keywords

  • OREXIN/HYPOCRETIN SYSTEM
  • SLEEP
  • STRESS
  • RESPONSES
  • BLOCKADE
  • ANXIETY
  • PROMOTION
  • HEALTHY
  • NEURONS
  • RAT

Cite this

Salvadore, G., Bonaventure, P., Shekhar, A., Johnson, P. L., Lord, B., Shireman, B. T., Lebold, T. P., Nepomuceno, D., Dugovic, C., Brooks, S., Zuiker, R., Bleys, C., Tatikola, K., Remmerie, B., Jacobs, G. E., Schruers, K., Moyer, J., Nash, A., Van Nueten, L. G. M., & Drevets, W. C. (2020). Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans. Translational Psychiatry, 10(1), [308]. https://doi.org/10.1038/s41398-020-00937-9