Transiently proliferating perivascular microglia harbor M1 type and precede cerebrovascular changes in a chronic hypertension model

Takashi Koizumi, Katsutoshi Taguchi, Ikuko Mizuta, Hiroe Toba, Makoto Ohigashi, Okihiro Onishi, Kazuya Ikoma, Seiji Miyata, Tetsuo Nakata, Masaki Tanaka, Sebastien Foulquier, Harry W. M. Steinbusch, Toshiki Mizuno*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number79
Number of pages13
JournalJournal of Neuroinflammation
Volume16
DOIs
Publication statusPublished - 10 Apr 2019

Keywords

  • Neuroinflammation
  • Cerebral small vessel disease
  • Chronic hypertension
  • Perivascular microglia
  • Proliferation
  • BLOOD-BRAIN-BARRIER
  • ANGIOTENSIN-II
  • ACTIVATED MICROGLIA
  • MACROPHAGES
  • INFLAMMATION
  • EXPRESSION
  • ISCHEMIA

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