Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility

Katja E. Odening; Ilona Bodi; Gerlind Franke; Raphaela Rieke; Anna Ryan de Medeiros; Stefanie Perez-Feliz; Hannah Fuerniss; Lea Mettke; Konstantin Michaelides; Corinna N. Lang; Johannes Steinfurt; Naga Deepa Pantulu; David Ziupa; Marius Menza; Manfred Zehender; Heiko Bugger; Remi Peyronnet; Jan C. Behrends; Zoltan Doleschall; Axel Zur Hausen; Christoph Bode; Genevieve Jolivet; Michael Brunner

doi:10.1093/eurheartj/ehy761

Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility

Katja E. Odening^*, Ilona Bodi, Gerlind Franke, Raphaela Rieke, Anna Ryan de Medeiros, Stefanie Perez-Feliz, Hannah Fuerniss, Lea Mettke, Konstantin Michaelides, Corinna N. Lang, Johannes Steinfurt, Naga Deepa Pantulu, David Ziupa, Marius Menza, Manfred Zehender, Heiko Bugger, Remi Peyronnet, Jan C. Behrends, Zoltan Doleschall, Axel Zur HausenChristoph Bode, Genevieve Jolivet, Michael Brunner

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

15 Citations (Web of Science)

Original language	English
Pages (from-to)	842-853
Number of pages	12
Journal	European Heart Journal
Volume	40
Issue number	10
DOIs	https://doi.org/10.1093/eurheartj/ehy761
Publication status	Published - 7 Mar 2019

Keywords

Short-QT syndrome
Animal models
Cardiac repolarization
Ion channels
Electrical remodelling
Arrhythmia
SUDDEN-DEATH
MUTATION

Access to Document

10.1093/eurheartj/ehy761

Cite this

Odening, K. E., Bodi, I., Franke, G., Rieke, R., de Medeiros, A. R., Perez-Feliz, S., Fuerniss, H., Mettke, L., Michaelides, K., Lang, C. N., Steinfurt, J., Pantulu, N. D., Ziupa, D., Menza, M., Zehender, M., Bugger, H., Peyronnet, R., Behrends, J. C., Doleschall, Z., ... Brunner, M. (2019). Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility. European Heart Journal, 40(10), 842-853. https://doi.org/10.1093/eurheartj/ehy761

Odening, Katja E. ; Bodi, Ilona ; Franke, Gerlind ; Rieke, Raphaela ; de Medeiros, Anna Ryan ; Perez-Feliz, Stefanie ; Fuerniss, Hannah ; Mettke, Lea ; Michaelides, Konstantin ; Lang, Corinna N. ; Steinfurt, Johannes ; Pantulu, Naga Deepa ; Ziupa, David ; Menza, Marius ; Zehender, Manfred ; Bugger, Heiko ; Peyronnet, Remi ; Behrends, Jan C. ; Doleschall, Zoltan ; Zur Hausen, Axel ; Bode, Christoph ; Jolivet, Genevieve ; Brunner, Michael. / Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility. In: European Heart Journal. 2019 ; Vol. 40, No. 10. pp. 842-853.

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title = "Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility",

keywords = "Short-QT syndrome, Animal models, Cardiac repolarization, Ion channels, Electrical remodelling, Arrhythmia, SUDDEN-DEATH, MUTATION",

author = "Odening, {Katja E.} and Ilona Bodi and Gerlind Franke and Raphaela Rieke and {de Medeiros}, {Anna Ryan} and Stefanie Perez-Feliz and Hannah Fuerniss and Lea Mettke and Konstantin Michaelides and Lang, {Corinna N.} and Johannes Steinfurt and Pantulu, {Naga Deepa} and David Ziupa and Marius Menza and Manfred Zehender and Heiko Bugger and Remi Peyronnet and Behrends, {Jan C.} and Zoltan Doleschall and {Zur Hausen}, Axel and Christoph Bode and Genevieve Jolivet and Michael Brunner",

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doi = "10.1093/eurheartj/ehy761",

language = "English",

volume = "40",

pages = "842--853",

journal = "European Heart Journal",

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Odening, KE, Bodi, I, Franke, G, Rieke, R, de Medeiros, AR, Perez-Feliz, S, Fuerniss, H, Mettke, L, Michaelides, K, Lang, CN, Steinfurt, J, Pantulu, ND, Ziupa, D, Menza, M, Zehender, M, Bugger, H, Peyronnet, R, Behrends, JC, Doleschall, Z, Zur Hausen, A, Bode, C, Jolivet, G & Brunner, M 2019, 'Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility', European Heart Journal, vol. 40, no. 10, pp. 842-853. https://doi.org/10.1093/eurheartj/ehy761

Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility. / Odening, Katja E.; Bodi, Ilona; Franke, Gerlind; Rieke, Raphaela; de Medeiros, Anna Ryan; Perez-Feliz, Stefanie; Fuerniss, Hannah; Mettke, Lea; Michaelides, Konstantin; Lang, Corinna N.; Steinfurt, Johannes; Pantulu, Naga Deepa; Ziupa, David; Menza, Marius; Zehender, Manfred; Bugger, Heiko; Peyronnet, Remi; Behrends, Jan C.; Doleschall, Zoltan; Zur Hausen, Axel; Bode, Christoph; Jolivet, Genevieve; Brunner, Michael.

In: European Heart Journal, Vol. 40, No. 10, 07.03.2019, p. 842-853.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility

AU - Odening, Katja E.

AU - Bodi, Ilona

AU - Franke, Gerlind

AU - Rieke, Raphaela

AU - de Medeiros, Anna Ryan

AU - Perez-Feliz, Stefanie

AU - Fuerniss, Hannah

AU - Mettke, Lea

AU - Michaelides, Konstantin

AU - Lang, Corinna N.

AU - Steinfurt, Johannes

AU - Pantulu, Naga Deepa

AU - Ziupa, David

AU - Menza, Marius

AU - Zehender, Manfred

AU - Bugger, Heiko

AU - Peyronnet, Remi

AU - Behrends, Jan C.

AU - Doleschall, Zoltan

AU - Zur Hausen, Axel

AU - Bode, Christoph

AU - Jolivet, Genevieve

AU - Brunner, Michael

PY - 2019/3/7

Y1 - 2019/3/7

KW - Short-QT syndrome

KW - Animal models

KW - Cardiac repolarization

KW - Ion channels

KW - Electrical remodelling

KW - Arrhythmia

KW - SUDDEN-DEATH

KW - MUTATION

U2 - 10.1093/eurheartj/ehy761

DO - 10.1093/eurheartj/ehy761

M3 - Article

C2 - 30496390

VL - 40

SP - 842

EP - 853

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

IS - 10

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Odening KE, Bodi I, Franke G, Rieke R, de Medeiros AR, Perez-Feliz S et al. Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility. European Heart Journal. 2019 Mar 7;40(10):842-853. https://doi.org/10.1093/eurheartj/ehy761