@article{f223526e76414fe99b02340d170507f1,
title = "Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity:: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes",
abstract = "Impulsive and compulsive behaviors have both been observed in individuals with obesity. The co-occurrence of obesity and type 2 diabetes (T2D) is more strongly associated with impulsivity, although there are no conclusive results yet. A multidimensional assessment of impulsivity and compulsivity was conducted in individuals with obesity in the absence or presence of T2D, compared with healthy, normal-weight individuals, with highly impulsive patients (gambling disorders), and with highly compulsive patients (anorexia nervosa). Decision making and novelty seeking were used to measure impulsivity, and cognitive flexibility and harm avoidance were used for compulsivity. For impulsivity, patients with obesity and T2D showed poorer decision-making ability compared with healthy individuals. For compulsivity, individuals with only obesity presented less cognitive flexibility and high harm avoidance; these dimensions were not associated with obesity with T2D. This study contributes to the knowledge of the mechanisms associated with diabetes and its association with impulsive-compulsive behaviors, confirming the hypothesis that patients with obesity and T2D would be characterized by higher levels of impulsivity.",
keywords = "impulsivity, compulsivity, decision making, cognitive flexibility, type 2 diabetes, novelty seeking, harm avoidance, PERSONALITY-CHARACTERISTICS, INDIVIDUAL-DIFFERENCES, MEASUREMENT ISSUES, TEMPERAMENT, MECHANISMS, OVERWEIGHT, DISORDERS, CHARACTER, DOPAMINE, FACETS",
author = "G. Testa and B. Mora-Maltas and L. Camacho-Barcia and R. Granero and I. Lucas and Z. Agueera and S. Jimenez-Murcia and R. Banos and V. Bertaina-Anglade and C. Botella and M. Bullo and F.F. Casanueva and S. Dalsgaard and J.M. Fernandez-Real and B. Franke and G. Fruehbeck and M. Fito and C. Gomez-Martinez and X. Pinto and G. Poelmans and F.J. Tinahones and R.D. Torre and J. Salas-Salvado and L. Serra-Majem and S. Vos and T. Wimberley and F. Fernandez-Aranda",
note = "Funding Information: Funding: This manuscript and research were supported by grants from the Instituto de Salud Carlos III (ISCIII) (FIS PI14/00290, PI17/01167 and PI20/132) and (PI13/00462, PI16/00501, PI19/00576), by the SLT006/17/00246 grant, funded by the Department of Health of the Generalitat de Catalunya by the call “Acci{\'o} instrumental de programes de recerca orientats en l{\textquoteright}{\`a}mbit de la recerca i la innovaci{\'o} en salut” (PERIS) and co-funded by FEDER funds/European Regional Development Fund (ERDF), a way to build Europe. CIBERObn is an initiative of ISCIII. This research was also partially funded by EU-H2020 grants (Eat2beNICE/H2020-SFS-2016-2, Ref 728018; PRIME/H2020-SC1-BHC-2018-2020, Ref: 847879). CG-M receives a predoctoral grant from the University of Rovira i Virgili (2020PMF-PIPF-37). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. Funding Information: Acknowledgments: We thank CERCA Programme/Generalitat de Catalunya for institutional support. This work is partially supported by ICREA under the ICREA Academia programme. Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2021",
month = dec,
day = "1",
doi = "10.3390/nu13124426",
language = "English",
volume = "13",
journal = "Nutrients",
issn = "2072-6643",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "12",
}