Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

Antonio Cuadrado, Gina Manda, Ahmed Hassan, Maria Alcaraz, Coral Barbas, Andreas Daiber, Pietro Ghezzi, Rafael Leon, Manuela G. Lopez, Baldo Oliva, Marta Pajares, Ana I. Rojo, Natalia Robledinos-Anton, Angela M. Valverde, Emre Guney, Harald H. H. W. Schmidt

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Pages (from-to)348-383
Number of pages36
JournalPharmacological Reviews
Volume70
Issue number2
DOIs
Publication statusPublished - 1 Apr 2018

Keywords

  • NF-KAPPA-B
  • PROTEIN-PROTEIN INTERACTION
  • FUMARIC-ACID ESTERS
  • EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
  • TYPE-2 DIABETES-MELLITUS
  • GLYCOGEN-SYNTHASE KINASE
  • TUMOR-SUPPRESSOR PTEN
  • HEME OXYGENASE 1
  • GENE PROMOTER POLYMORPHISM
  • PLACEBO-CONTROLLED PHASE-3

Cite this