Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

Antonio Cuadrado*, Gina Manda, Ahmed Hassan, Maria Alcaraz, Coral Barbas, Andreas Daiber, Pietro Ghezzi, Rafael Leon, Manuela G. Lopez, Baldo Oliva, Marta Pajares, Ana I. Rojo, Natalia Robledinos-Anton, Angela M. Valverde, Emre Guney*, Harald H. H. W. Schmidt

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Pages (from-to)348-383
Number of pages36
JournalPharmacological Reviews
Volume70
Issue number2
DOIs
Publication statusPublished - 1 Apr 2018

Keywords

  • NF-KAPPA-B
  • PROTEIN-PROTEIN INTERACTION
  • FUMARIC-ACID ESTERS
  • EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
  • TYPE-2 DIABETES-MELLITUS
  • GLYCOGEN-SYNTHASE KINASE
  • TUMOR-SUPPRESSOR PTEN
  • HEME OXYGENASE 1
  • GENE PROMOTER POLYMORPHISM
  • PLACEBO-CONTROLLED PHASE-3

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