Towards an animal-free integrated testing strategy for the identification of skin sensitizing chemicals

J.W. van der Veen

    Research output: ThesisDoctoral ThesisInternal

    Abstract

    Determining whether chemical materials can cause an allergy on the skin (contact allergy) can occur in the near future without using laboratory animals. That is the conclusion of this PhD research that was carried out at the RIVM and Maastricht University as part of the Netherlands Toxicogenomics Centre project. Combining different test methods in a test strategy leads to a better prediction than using laboratory animals or simple tests. The new strategy is promising, but cannot yet fully replace animal testing.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • Maastricht University
    Supervisors/Advisors
    • van Loveren, Henk, Supervisor
    • Ezendam, J., Advisor, External person
    Award date9 Oct 2015
    Publication statusPublished - 2015

    Keywords

    • allergy test
    • chemical materials
    • contact allergy
    • animal testing

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