Towards a testing strategy for the identification of respiratory sensitizing chemicals

Sander Dik

Research output: ThesisDoctoral ThesisInternal

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Abstract

Asthma in the workplace is a major problem worldwide. The studies constituting this dissertation provide more insight into work-related asthma and offer tools for developing a test strategy to detect substances causing this type of asthma. Computer models, a chemical analysis and a biological analysis were used to achieve this goal. Each of these methods were shown to be useful yet insufficient when applied separately. However, the combination of these methods allows far more substances to be assessed more accurately in terms of predicting whether or not they cause work-related asthma.
Original languageEnglish
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • van Loveren, Henk, Supervisor
  • Ezendam, J., Supervisor, External person
Award date16 Nov 2018
Place of PublicationMaastricht
Publisher
Print ISBNs9789461829184
DOIs
Publication statusPublished - 2018

Keywords

  • work-related asthma
  • test strategy
  • substances
  • computer models

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