TY - JOUR
T1 - Tissue Doppler indexes of left ventricular systolic function in relation to the pulsatile and steady components of blood pressure in a general population
AU - Sakiewicz, Wojciech
AU - Kuznetsova, Tatiana
AU - Kloch-Badelek, Malgorzata
AU - D'hooge, Jan
AU - Ryabikov, Andrew
AU - Kunicka, Katarzyna
AU - Swierblewska, Ewa
AU - Thijs, Lutgarde
AU - Jin, Yu
AU - Loster, Magdalena
AU - Malyutina, Sofia
AU - Stolarz-Skrzypek, Katarzyna
AU - Kawecka-Jaszcz, Kalina
AU - Narkiewicz, Krzysztof
AU - Staessen, Jan A.
PY - 2012/2
Y1 - 2012/2
N2 - Objectives: To our knowledge, no population study described the association of the radial and longitudinal components of left ventricular strain with blood pressure (BP) components in continuous analyses. We therefore investigated these associations in participants randomly recruited from the general population in the framework of the family-based European Project on Genes in Hypertension. Methods: In 334 participants (55.4% women; mean age, 43.6 year), using tissue Doppler imaging (TDI), we measured the end-systolic longitudinal strain (mean 20.9%) and peak systolic strain rate (1.29 s(-1)) from the basal portion of the left ventricular inferior and posterior free walls and radial stain (51.1%) and strain rate (3.40 s(-1)) of the left ventricular posterior wall. Models included in addition to covariables and confounders both SBP and DBP or both pulse pressure (PP) and mean arterial pressure (MAP). Effect sizes were expressed per 1-SD increase in BP. Results: Longitudinal strain (-0.62%; P = 0.04 and -0.64%; P = 0.007), but not strain rate, decreased with DBP and MAP. Radial strain (4.0 and -3.4%; P
AB - Objectives: To our knowledge, no population study described the association of the radial and longitudinal components of left ventricular strain with blood pressure (BP) components in continuous analyses. We therefore investigated these associations in participants randomly recruited from the general population in the framework of the family-based European Project on Genes in Hypertension. Methods: In 334 participants (55.4% women; mean age, 43.6 year), using tissue Doppler imaging (TDI), we measured the end-systolic longitudinal strain (mean 20.9%) and peak systolic strain rate (1.29 s(-1)) from the basal portion of the left ventricular inferior and posterior free walls and radial stain (51.1%) and strain rate (3.40 s(-1)) of the left ventricular posterior wall. Models included in addition to covariables and confounders both SBP and DBP or both pulse pressure (PP) and mean arterial pressure (MAP). Effect sizes were expressed per 1-SD increase in BP. Results: Longitudinal strain (-0.62%; P = 0.04 and -0.64%; P = 0.007), but not strain rate, decreased with DBP and MAP. Radial strain (4.0 and -3.4%; P
KW - blood pressure
KW - left ventricular function
KW - population
KW - strain
U2 - 10.1097/HJH.0b013e32834ea41b
DO - 10.1097/HJH.0b013e32834ea41b
M3 - Article
C2 - 22179084
SN - 0263-6352
VL - 30
SP - 403
EP - 410
JO - Journal of Hypertension
JF - Journal of Hypertension
IS - 2
ER -