Timing of definitive fixation of major long bone fractures: Can fat embolism syndrome be prevented?

Taco J. Blokhuis; Hans-Christoph Pape; Jan-Paul Frolke

doi:10.1016/j.injury.2017.04.015

Timing of definitive fixation of major long bone fractures: Can fat embolism syndrome be prevented?

Taco J. Blokhuis^*, Hans-Christoph Pape, Jan-Paul Frolke

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Fat embolism is common in patients with major fractures, but leads to devastating consequences, named fat embolism syndrome (FES) in some. Despite advances in treatment strategies regarding the timing of definitive fixation of major fractures, FES still occurs in patients. In this overview, current literature is reviewed and optimal treatment strategies for patients with multiple traumatic injuries, including major fractures, are discussed. Considering the multifactorial etiology of FES, including mechanical and biochemical pathways, FES cannot be prevented in all patients. However, screening for symptoms of FES should be standard in the pre-operative work-up of these patients, prior to definitive fixation of major fractures. (C) 2017 Published by Elsevier Ltd.

Original language	English
Pages (from-to)	S3-S6
Number of pages	4
Journal	Injury-International Journal of the Care of the Injured
Volume	48
DOIs	https://doi.org/10.1016/j.injury.2017.04.015
Publication status	Published - Jun 2017

Keywords

Fat embolism
Fat embolism syndrome
Safe Definitive Surgery (SDS)
Damage control orthopaedics
Femur fracture
FEMORAL-SHAFT FRACTURES
DAMAGE CONTROL ORTHOPEDICS
MULTIPLE INJURIES
EXTERNAL FIXATION
STABILIZATION
SURGERY
TRAUMA
CARE
MANAGEMENT

Access to Document

10.1016/j.injury.2017.04.015

Cite this

@article{08423131b8b141f4a8d30839a9950c24,

title = "Timing of definitive fixation of major long bone fractures: Can fat embolism syndrome be prevented?",

abstract = "Fat embolism is common in patients with major fractures, but leads to devastating consequences, named fat embolism syndrome (FES) in some. Despite advances in treatment strategies regarding the timing of definitive fixation of major fractures, FES still occurs in patients. In this overview, current literature is reviewed and optimal treatment strategies for patients with multiple traumatic injuries, including major fractures, are discussed. Considering the multifactorial etiology of FES, including mechanical and biochemical pathways, FES cannot be prevented in all patients. However, screening for symptoms of FES should be standard in the pre-operative work-up of these patients, prior to definitive fixation of major fractures. (C) 2017 Published by Elsevier Ltd.",

keywords = "Fat embolism, Fat embolism syndrome, Safe Definitive Surgery (SDS), Damage control orthopaedics, Femur fracture, FEMORAL-SHAFT FRACTURES, DAMAGE CONTROL ORTHOPEDICS, MULTIPLE INJURIES, EXTERNAL FIXATION, STABILIZATION, SURGERY, TRAUMA, CARE, MANAGEMENT",

author = "Blokhuis, {Taco J.} and Hans-Christoph Pape and Jan-Paul Frolke",

year = "2017",

month = jun,

doi = "10.1016/j.injury.2017.04.015",

language = "English",

volume = "48",

pages = "S3--S6",

journal = "Injury-International Journal of the Care of the Injured",

issn = "0020-1383",

publisher = "ELSEVIER SCI LTD",

}

TY - JOUR

T1 - Timing of definitive fixation of major long bone fractures

T2 - Can fat embolism syndrome be prevented?

AU - Blokhuis, Taco J.

AU - Pape, Hans-Christoph

AU - Frolke, Jan-Paul

PY - 2017/6

Y1 - 2017/6

N2 - Fat embolism is common in patients with major fractures, but leads to devastating consequences, named fat embolism syndrome (FES) in some. Despite advances in treatment strategies regarding the timing of definitive fixation of major fractures, FES still occurs in patients. In this overview, current literature is reviewed and optimal treatment strategies for patients with multiple traumatic injuries, including major fractures, are discussed. Considering the multifactorial etiology of FES, including mechanical and biochemical pathways, FES cannot be prevented in all patients. However, screening for symptoms of FES should be standard in the pre-operative work-up of these patients, prior to definitive fixation of major fractures. (C) 2017 Published by Elsevier Ltd.

AB - Fat embolism is common in patients with major fractures, but leads to devastating consequences, named fat embolism syndrome (FES) in some. Despite advances in treatment strategies regarding the timing of definitive fixation of major fractures, FES still occurs in patients. In this overview, current literature is reviewed and optimal treatment strategies for patients with multiple traumatic injuries, including major fractures, are discussed. Considering the multifactorial etiology of FES, including mechanical and biochemical pathways, FES cannot be prevented in all patients. However, screening for symptoms of FES should be standard in the pre-operative work-up of these patients, prior to definitive fixation of major fractures. (C) 2017 Published by Elsevier Ltd.

KW - Fat embolism

KW - Fat embolism syndrome

KW - Safe Definitive Surgery (SDS)

KW - Damage control orthopaedics

KW - Femur fracture

KW - FEMORAL-SHAFT FRACTURES

KW - DAMAGE CONTROL ORTHOPEDICS

KW - MULTIPLE INJURIES

KW - EXTERNAL FIXATION

KW - STABILIZATION

KW - SURGERY

KW - TRAUMA

KW - CARE

KW - MANAGEMENT

U2 - 10.1016/j.injury.2017.04.015

DO - 10.1016/j.injury.2017.04.015

M3 - Article

C2 - 28449860

SN - 0020-1383

VL - 48

SP - S3-S6

JO - Injury-International Journal of the Care of the Injured

JF - Injury-International Journal of the Care of the Injured

ER -