Timing of definitive fixation of major long bone fractures: Can fat embolism syndrome be prevented?

Taco J. Blokhuis*, Hans-Christoph Pape, Jan-Paul Frolke

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Web of Science)

Abstract

Fat embolism is common in patients with major fractures, but leads to devastating consequences, named fat embolism syndrome (FES) in some. Despite advances in treatment strategies regarding the timing of definitive fixation of major fractures, FES still occurs in patients. In this overview, current literature is reviewed and optimal treatment strategies for patients with multiple traumatic injuries, including major fractures, are discussed. Considering the multifactorial etiology of FES, including mechanical and biochemical pathways, FES cannot be prevented in all patients. However, screening for symptoms of FES should be standard in the pre-operative work-up of these patients, prior to definitive fixation of major fractures. (C) 2017 Published by Elsevier Ltd.

Original languageEnglish
Pages (from-to)S3-S6
Number of pages4
JournalInjury-International Journal of the Care of the Injured
Volume48
DOIs
Publication statusPublished - Jun 2017

Keywords

  • Fat embolism
  • Fat embolism syndrome
  • Safe Definitive Surgery (SDS)
  • Damage control orthopaedics
  • Femur fracture
  • FEMORAL-SHAFT FRACTURES
  • DAMAGE CONTROL ORTHOPEDICS
  • MULTIPLE INJURIES
  • EXTERNAL FIXATION
  • STABILIZATION
  • SURGERY
  • TRAUMA
  • CARE
  • MANAGEMENT

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