Time to diagnosis in young-onset dementia as compared with late-onset dementia

D. van Vliet, M. E. de Vugt*, C. Bakker, Y. A. L. Pijnenburg, M. J. F. J. Vernooij-Dassen, R. T. C. M. Koopmans, F. R. J. Verhey

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

111 Citations (Web of Science)

Abstract

Background. The extent to which specific factors influence diagnostic delays in dementia is unclear. Therefore, the aim of the present study was to compare duration from symptom onset to diagnosis for young-onset dementia (YOD) and late-onset dementia (LOD) and to assess the effect of age at onset, type of dementia, gender, living situation, education and family history of dementia on this duration. Method. Data on 235 YOD and 167 LOD patients collected from caregivers from two prospective cohort studies were used. Multiple linear regression analysis was performed. Results. The duration between symptom onset and the diagnosis of YOD exceeded that of LOD by an average of 1.6 years (2.8 v. 4.4 years). Young age and being diagnosed with frontotemporal dementia were related to increases in the time to diagnosis. Subjects with vascular dementia experienced shorter time to diagnosis. Conclusions. There is a need to raise special awareness of YOD to facilitate a timely diagnosis.
Original languageEnglish
Pages (from-to)423-432
JournalPsychological Medicine
Volume43
Issue number2
DOIs
Publication statusPublished - Feb 2013

Keywords

  • Diagnostic delay
  • early onset dementia
  • presenile
  • time to diagnosis
  • young onset dementia

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