Time-series analysis of gene expression profiles induced by nitrosamides and nitrosamines elucidates modes of action underlying their genotoxicity in human colon cells

Dennie G. A. J. Hebels, Karen J. J. Brauers, Marcel H. M. van Herwijnen, Panagiotis A. Georgiadis, Soterios A. Kyrtopoulos, Jos C. S. Kleinjans, Theo M. C. M. de Kok

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)232-241
JournalToxicology Letters
Volume207
Issue number3
DOIs
Publication statusPublished - 15 Dec 2011

Keywords

  • Toxicogenomics
  • N-nitroso compounds
  • Time-series
  • Alkylating agents
  • O(6)-methylguanine
  • Colon carcinogenesis

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