Time from diagnosis to institutionalization and death in people with dementia

Karlijn J Joling; Olin Janssen; Anneke L Francke; Robert A Verheij; Birgit I Lissenberg-Witte; Pieter-Jelle Visser; Hein P J van Hout

doi:10.1002/alz.12063

Time from diagnosis to institutionalization and death in people with dementia

Karlijn J Joling^*, Olin Janssen, Anneke L Francke, Robert A Verheij, Birgit I Lissenberg-Witte, Pieter-Jelle Visser, Hein P J van Hout

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

INTRODUCTION: Reliable estimates of time from diagnosis until institutionalization and death in people with dementia from routine nationally representative databases are lacking.

METHODS: We selected 9230 people with dementia and 24,624 matched controls from family physicians' electronic records linked with national administrative databases to analyze time until institutionalization and death and associated factors.

RESULTS: Median time from recorded diagnosis until institutionalization and until death for people with dementia was 3.9 and 5.0 years, respectively, which was considerably shorter than for controls. Once institutionalized, median time to death was longer for persons with dementia (2.5 years) than for controls (1.2 years). Older age and receiving home care were the strongest predictors of shorter time until institutionalization and death in people with dementia. Gender, cohabitation, migration status, frailty, polypharmacy, and dementia medication were other significant factors.

DISCUSSION: The estimates could help to inform patients, their families, and policymakers about probable trajectories.

Original language	English
Pages (from-to)	662-671
Number of pages	10
Journal	Alzheimer's & Dementia
Volume	16
Issue number	4
DOIs	https://doi.org/10.1002/alz.12063
Publication status	Published - Apr 2020

Keywords

care trajectories
data linkage
primary care
registry data
risk factors
survival
time to institutionalization
NURSING-HOME ADMISSION
PRIMARY-CARE
ALZHEIMERS-DISEASE
INCIDENT DEMENTIA
OLDER-ADULTS
PREDICTORS
FRAILTY
PREVALENCE
SURVIVAL
OUTCOMES

Access to Document

10.1002/alz.12063Licence: CC BY-NC

Cite this

@article{ecfa56db4b634c7e87c81af2b3f0665e,

title = "Time from diagnosis to institutionalization and death in people with dementia",

abstract = "INTRODUCTION: Reliable estimates of time from diagnosis until institutionalization and death in people with dementia from routine nationally representative databases are lacking.METHODS: We selected 9230 people with dementia and 24,624 matched controls from family physicians' electronic records linked with national administrative databases to analyze time until institutionalization and death and associated factors.RESULTS: Median time from recorded diagnosis until institutionalization and until death for people with dementia was 3.9 and 5.0 years, respectively, which was considerably shorter than for controls. Once institutionalized, median time to death was longer for persons with dementia (2.5 years) than for controls (1.2 years). Older age and receiving home care were the strongest predictors of shorter time until institutionalization and death in people with dementia. Gender, cohabitation, migration status, frailty, polypharmacy, and dementia medication were other significant factors.DISCUSSION: The estimates could help to inform patients, their families, and policymakers about probable trajectories.",

keywords = "care trajectories, data linkage, primary care, registry data, risk factors, survival, time to institutionalization, NURSING-HOME ADMISSION, PRIMARY-CARE, ALZHEIMERS-DISEASE, INCIDENT DEMENTIA, OLDER-ADULTS, PREDICTORS, FRAILTY, PREVALENCE, SURVIVAL, OUTCOMES",

author = "Joling, {Karlijn J} and Olin Janssen and Francke, {Anneke L} and Verheij, {Robert A} and Lissenberg-Witte, {Birgit I} and Pieter-Jelle Visser and {van Hout}, {Hein P J}",

note = "{\textcopyright} 2019 The Authors. Alzheimer's & Dementia published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association.",

year = "2020",

month = apr,

doi = "10.1002/alz.12063",

language = "English",

volume = "16",

pages = "662--671",

journal = "Alzheimer's & Dementia",

issn = "1552-5260",

publisher = "Elsevier Science",

number = "4",

}

TY - JOUR

T1 - Time from diagnosis to institutionalization and death in people with dementia

AU - Joling, Karlijn J

AU - Janssen, Olin

AU - Francke, Anneke L

AU - Verheij, Robert A

AU - Lissenberg-Witte, Birgit I

AU - Visser, Pieter-Jelle

AU - van Hout, Hein P J

PY - 2020/4

Y1 - 2020/4

N2 - INTRODUCTION: Reliable estimates of time from diagnosis until institutionalization and death in people with dementia from routine nationally representative databases are lacking.METHODS: We selected 9230 people with dementia and 24,624 matched controls from family physicians' electronic records linked with national administrative databases to analyze time until institutionalization and death and associated factors.RESULTS: Median time from recorded diagnosis until institutionalization and until death for people with dementia was 3.9 and 5.0 years, respectively, which was considerably shorter than for controls. Once institutionalized, median time to death was longer for persons with dementia (2.5 years) than for controls (1.2 years). Older age and receiving home care were the strongest predictors of shorter time until institutionalization and death in people with dementia. Gender, cohabitation, migration status, frailty, polypharmacy, and dementia medication were other significant factors.DISCUSSION: The estimates could help to inform patients, their families, and policymakers about probable trajectories.

AB - INTRODUCTION: Reliable estimates of time from diagnosis until institutionalization and death in people with dementia from routine nationally representative databases are lacking.METHODS: We selected 9230 people with dementia and 24,624 matched controls from family physicians' electronic records linked with national administrative databases to analyze time until institutionalization and death and associated factors.RESULTS: Median time from recorded diagnosis until institutionalization and until death for people with dementia was 3.9 and 5.0 years, respectively, which was considerably shorter than for controls. Once institutionalized, median time to death was longer for persons with dementia (2.5 years) than for controls (1.2 years). Older age and receiving home care were the strongest predictors of shorter time until institutionalization and death in people with dementia. Gender, cohabitation, migration status, frailty, polypharmacy, and dementia medication were other significant factors.DISCUSSION: The estimates could help to inform patients, their families, and policymakers about probable trajectories.

KW - care trajectories

KW - data linkage

KW - primary care

KW - registry data

KW - risk factors

KW - survival

KW - time to institutionalization

KW - NURSING-HOME ADMISSION

KW - PRIMARY-CARE

KW - ALZHEIMERS-DISEASE

KW - INCIDENT DEMENTIA

KW - OLDER-ADULTS

KW - PREDICTORS

KW - FRAILTY

KW - PREVALENCE

KW - SURVIVAL

KW - OUTCOMES

U2 - 10.1002/alz.12063

DO - 10.1002/alz.12063

M3 - Article

C2 - 32072728

SN - 1552-5260

VL - 16

SP - 662

EP - 671

JO - Alzheimer's & Dementia

JF - Alzheimer's & Dementia

IS - 4

ER -