Thrombin generation and platelet activation in cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: A prospective cohort study

Sven Van Poucke, Dana Huskens, Kurt Van der Speeten, Mark Roest, Bart Lauwereins, Ming-Hua Zheng, Seppe Dehaene, Joris Penders, Abraham Marcus, Marcus Lance

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numbere0193657
Number of pages20
JournalPLOS ONE
Volume13
Issue number6
DOIs
Publication statusPublished - 21 Jun 2018

Keywords

  • WHOLE-BODY HYPERTHERMIA
  • INDUCED IMMUNE THROMBOCYTOPENIA
  • PERITONEAL CARCINOMATOSIS
  • HEMOSTATIC FUNCTIONS
  • OXALIPLATIN
  • MANAGEMENT
  • 5-FLUOROURACIL
  • DRUGS
  • THROMBOELASTOMETRY
  • HYPERCOAGULABILITY
  • Prospective Studies
  • Humans
  • Middle Aged
  • Male
  • Cytoreduction Surgical Procedures
  • Neoplasm Metastasis
  • Hyperthermia, Induced
  • Adult
  • Female
  • Thrombin Time
  • Thrombelastography
  • Peritoneal Neoplasms/blood
  • Thrombin/metabolism
  • Platelet Activation
  • Aged

Cite this

Van Poucke, S., Huskens, D., Van der Speeten, K., Roest, M., Lauwereins, B., Zheng, M-H., Dehaene, S., Penders, J., Marcus, A., & Lance, M. (2018). Thrombin generation and platelet activation in cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: A prospective cohort study. PLOS ONE, 13(6), [e0193657]. https://doi.org/10.1371/journal.pone.0193657