There's something in the air : Volatile organic compounds in exhaled breath in pulmonary diseases

J.J.B.N. van Berkel

    Research output: ThesisDoctoral ThesisInternal

    301 Downloads (Pure)


    This dissertation describes the development and application of a method in which by measuring volatile organic compounds (VOCs) in exhaled breath various inflammation-related pulmonary diseases can be determined and studied. The exhaled breath of people with diseases such as cystic fibrosis and COPD (chronic obstructive pulmonary disease) turns out to differ from that of healthy people. By means of advanced classification models (support vector machines) it is possible to select a limited number of VOCs that can subsequently be used to diagnose. Diagnoses by means of the exhaled breath turned out correct in over 90% of the cases.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • Maastricht University
    • van Schooten, Frederik, Supervisor
    • Wouters, Emiel, Supervisor
    • Dallinga, Jan, Co-Supervisor
    Award date3 Nov 2010
    Place of PublicationMaastricht
    Print ISBNs978-94-6159-011-4
    Publication statusPublished - 1 Jan 2010


    • VOCs
    • diagnosis
    • pulmonary diseases

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