This dissertation describes the development and application of a method in which by measuring volatile organic compounds (VOCs) in exhaled breath various inflammation-related pulmonary diseases can be determined and studied. The exhaled breath of people with diseases such as cystic fibrosis and COPD (chronic obstructive pulmonary disease) turns out to differ from that of healthy people. By means of advanced classification models (support vector machines) it is possible to select a limited number of VOCs that can subsequently be used to diagnose. Diagnoses by means of the exhaled breath turned out correct in over 90% of the cases.
|Qualification||Doctor of Philosophy|
|Award date||3 Nov 2010|
|Place of Publication||Maastricht|
|Publication status||Published - 1 Jan 2010|
- pulmonary diseases